期刊
ORGANIC LETTERS
卷 22, 期 7, 页码 2724-2729出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c00688
关键词
-
资金
- National Natural Science Foundation of China [21772183]
- Fundamental Rese arch Funds for the Cent ral Universities [WK2060190086]
- 1000-Youth Talents Plan
- University of Science and Technology of China
Herein, we report a nickel-catalyzed asymmetric two-component reductive dicarbofunctionalization of aryl iodide-tethered unactivated alkenes using benzyl chlorides as the challenging coupling partner. This arylbenzylation reaction enables the efficient synthesis of diverse benzene-fused cyclic compounds bearing a quaternary stereocenter with a high tolerance of sensitive functionalities in highly enantioselective manner. The preliminary mechanistic investigations suggest a radical chain reaction mechanism.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据