Article
Medicine, General & Internal
Melle Spruijt, Manon Kerkhof, Marian Rombouts, Richard Brohet, Wenche Klerkx
Summary: This randomized controlled trial aims to investigate the efficacy and safety of botulinum toxin A (BTA) injection compared with placebo injections in women with chronic pelvic pain. The study includes 94 women with at least 6 months of pelvic pain without anatomical cause and pelvic floor hypertonicity. The findings will be disseminated through international conferences and peer-reviewed scientific journals.
Review
Health Care Sciences & Services
Kent Yu-Hsien Lin, Yi-Chuan Chang, Wen-Chi Lu, Peddanna Kotha, Yi-Hung Chen, Cheng-Hao Tu
Summary: Chronic pelvic pain (CPP) refers to the pain in the pelvic region that lasts longer than six months. Monotherapy with medication may not be sufficient for CPP pain management, and multidisciplinary approaches are recommended. This study evaluated the efficacy of acupuncture compared to a control group for managing CPP. A meta-analysis of 17 randomized controlled trials involving 1455 patients showed that acupuncture significantly decreased pain levels in both total pain scores and visual analogue scale/numerical rating scale data compared to the control group. Acupuncture as a monotherapy also resulted in significantly lower pain levels than the control group. These findings suggest that acupuncture may be beneficial for managing CPP pain, even when used as a standalone treatment.
Article
Public, Environmental & Occupational Health
Aakriti R. Carrubba, Jon O. Ebbert, Aaron C. Spaulding, David DeStephano, Christopher C. DeStephano
Summary: The study found that nearly one-quarter of chronic pelvic pain patients use cannabis regularly as an adjunct to their prescribed therapy, with most users reporting improvement in symptoms. Although side effects are common, the majority of users are optimistic about the potential of cannabis as a therapeutic option.
JOURNAL OF WOMENS HEALTH
(2021)
Review
Urology & Nephrology
Brian A. Parsons, Andrew P. Baranowski, Bary Berghmans, Jan Borovicka, Angela M. Cottrell, Paulo Dinis-Oliveira, Sohier Elneil, John Hughes, Bert E. J. Messelink, Amanda C. de C. Williams, Pedro Abreu-Mendes, Valentin Zumstein, Daniel S. Engeler
Summary: Management of chronic pelvic pain remains a huge challenge, with unimodal therapeutic options often unsuccessful. Individualised multimodal management appears to be the most promising approach, leading to improvement for a large proportion of patients. The European Association of Urology Chronic Pelvic Pain Guideline Group provides an overview of important concepts for successfully diagnosing and treating this challenging disease.
Article
Anesthesiology
Christopher M. Lam, Sarah A. Keim, Usman Latif
Summary: This study describes a novel fluoroscopic guided technique for pudendal nerve peripheral nerve stimulator (PNS) lead placement and implantation for the management of chronic pelvic pain (CPP). The technique can avoid important neurovascular structures near the pelvic outlet and may be a viable treatment option for medically refractory CPP.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Obstetrics & Gynecology
Sawsan As-Sanie, Sara R. Till, Andrew D. Schrepf, Kendall C. Griffith, Alex Tsodikov, Stacey A. Missmer, Daniel J. Clauw, Chad M. Brummett
Summary: While most women with chronic pelvic pain experience significant pain relief following hysterectomy, higher levels of centralized pain before the surgery are a strong predictor of persistent pelvic pain in the long term.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Medicine, General & Internal
Bradley John Halliday, Sarah Chatfield, Lee Cameron, Joanne Hosking, Jill Shawe, Annie Hawton, Christopher Hayward, Kirsty Carter, Jennifer A. Freeman
Summary: This study aims to evaluate the clinical effectiveness, cost-effectiveness, and acceptability of customised orthoses in postpartum women. It is a pragmatic, multicentre randomised controlled feasibility trial with an embedded qualitative study and economic evaluation. The participants will complete self-report questionnaires to assess pain, function, health-related quality of life, and healthcare resource use. Feasibility and acceptability will be assessed through recruitment and retention rates, data completion rates, and intervention adherence. Results will be disseminated to various stakeholders.
Review
Urology & Nephrology
Pedro Abreu-Mendes, Andrew P. Baranowski, Bary Berghmans, Jan Borovicka, Angela M. Cottrell, Paulo Dinis-Oliveira, Sohier Elneil, John Hughes, Bert E. J. Messelink, Victoria Tidman, Rui Pinto, Jure Tornic, Ida Flink, Brian A. Parsons, Valentin Zumstein, Daniel S. Engeler
Summary: Despite the high prevalence of myofascial pain in chronic pelvic pain syndromes, awareness and management of this component are lacking among health care providers. This review highlights the current state of research and expert opinions on the management of myofascial pain in chronic pelvic pain syndromes, emphasizing the importance of a multidisciplinary approach.
EUROPEAN UROLOGY FOCUS
(2023)
Review
Anesthesiology
K. Vincent, E. Evans
Summary: Chronic pelvic pain is a significant public health issue for women, impacting their quality of life. Management involves a variety of therapies and a multidisciplinary team approach is necessary.
Article
Urology & Nephrology
Priyanka Gupta, Robert Gallop, Theresa Spitznagle, Henry Lai, Frank Tu, John N. Krieger, J. Quentin Clemens, Catherine S. Bradley, Claire Yang, Siobhan Sutcliffe, Robert Moldwin, Karl Kreder, Jason Kutch, Larissa Rodriguez
Summary: This study found that 81% of UCPPS patients had pelvic floor muscle tenderness (PFT), compared to only 9% in the control group. Patients with higher PFT scores had more severe symptoms, worse quality of life, and more widespread nonpelvic pain.
JOURNAL OF UROLOGY
(2022)
Review
Biochemistry & Molecular Biology
Soo Youn Song, Ye Won Jung, WonKyo Shin, Mia Park, Geon Woo Lee, Soohwa Jeong, Sukjeong An, Kyoungmin Kim, Young Bok Ko, Ki Hwan Lee, Byung Hun Kang, Mina Lee, Heon Jong Yoo
Summary: Endometriosis, a common gynecologic disease, often leads to various pain symptoms such as dysmenorrhea, dyspareunia, and chronic pelvic pain. Inflammatory responses, nervous system sensitization, and altered distribution of nerve fibers may contribute to chronic pain in these patients. Understanding these mechanisms is crucial in guiding treatment decisions for endometriosis-related pain symptoms.
Article
Urology & Nephrology
Kelli Aibel, Robert Moldwin
Summary: The study developed and validated the Pelvic Pain Map as a reliable tool for assessing the location of pain in patients with chronic pelvic pain. The map incorporates input from experts and patient feedback to ensure its face validity. The findings suggest that the Pelvic Pain Map has the potential to guide treatment selection and monitor therapeutic response in patients with chronic pelvic pain.
Review
Biochemistry & Molecular Biology
Ana Catarina Neto, Mariana Santos-Pereira, Pedro Abreu-Mendes, Delminda Neves, Henrique Almeida, Francisco Cruz, Ana Charrua
Summary: The definitions of chronic pelvic/visceral pain have changed within international societies, greatly impacting research approaches. Recent studies highlight the significance of systemic changes and the central nervous system in the perpetuation of pelvic/visceral pain. As a result, researchers are utilizing animal models that replicate systemic changes, rather than organ- or tissue-specific models. This review discusses the advantages and disadvantages of bladder-centric and systemic models, highlighting central nervous system changes and pain-related behaviors. It also raises concerns about potential investigator bias and suggests new approaches for studying chronic pelvic/visceral pain through refined or novel animal models.
Article
Medicine, General & Internal
Monica Magarinos Lopez, Maria Jose Lobato Rodriguez, Angela Menendez Garcia, Sophie Garcia-Cid, Ana Royuela, Augusto Pereira
Summary: The study found that women with CPP have high levels of neuroticism, low extraversion, and low conscientiousness, along with moderate to severe levels of depression, high levels of trait and state anxiety, catastrophizing, and low pain acceptance. These psychological factors are important to consider in developing interventions to improve the clinical course of CPP.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Marie Timmermans, Michelle Nisolle, Geraldine Brichant, Laurie Henry, Evy Gillet, Betty Kellner, Stavros Karampelas
Summary: Chronic pelvic pain is commonly associated with additional pathologies such as adenomyosis and endometriosis. A retrospective study found that 40% of patients with associated pathologies did not experience relief from pelvic pain at the early follow-up and 32% at the 12-month follow-up after laparoscopic niche repair. Therefore, careful patient selection is important for uterine scar repair in patients with concomitant adenomyosis and endometriosis.
JOURNAL OF CLINICAL MEDICINE
(2023)