Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA

The extruded non-template strand determines the architecture of R-loops

(2019) Yeraldinne Carrasco-Salas et al.   NUCLEIC ACIDS RESEARCH

A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers

(2019) Gourish Mondal et al.   Nature Communications

Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells

(2019) Ana Cuadrado et al.   Cell Reports

R Loops: From Physiological to Pathological Roles

(2019) Tatiana García-Muse et al.   CELL

Bon voyage: A transcriptional journey around DNA breaks

(2019) Pierre Caron et al.   DNA REPAIR

Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization

(2018) Aleksandar Kojic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization

(2018) Aleksandar Kojic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Towards a Unified Model of SMC Complex Function

(2018) Markus Hassler et al.   CURRENT BIOLOGY

Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

(2018) Cornelia Meisenberg et al.   MOLECULAR CELL

The Emerging Role of Cohesin in the DNA Damage Response

(2018) Ireneusz Litwin et al.   Genes

Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates

(2017) Preston Countryman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1

(2017) Hai Dang Nguyen et al.   MOLECULAR CELL

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts

(2017) Petra van der Lelij et al.   eLife

Gene regulation and chromatin organization: relevance of cohesin mutations to human disease

(2016) Erwan Watrin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals

(2016) Lionel A. Sanz et al.   MOLECULAR CELL

The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends

(2016) Camille Gelot et al.   MOLECULAR CELL

Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA–DNA pairing

(2016) Jiangguo Lin et al.   NUCLEIC ACIDS RESEARCH

Nascent Connections: R-Loops and Chromatin Patterning

(2016) Frédéric Chédin   TRENDS IN GENETICS

Formation of Chromosomal Domains by Loop Extrusion

(2016) Geoffrey Fudenberg et al.   Cell Reports

Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2

(2016) Parminder Kaur et al.   Scientific Reports

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

R loops: new modulators of genome dynamics and function

(2015) José M. Santos-Pereira et al.   NATURE REVIEWS GENETICS

Cohesin gene mutations in tumorigenesis: from discovery to clinical significance

(2014) David A. Solomon et al.   BMB Reports

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

(2013) Jiangguo Lin et al.   NUCLEIC ACIDS RESEARCH

Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes

(2013) Craig D. Hughes et al.   NUCLEIC ACIDS RESEARCH

Characterization of the Interaction between the Cohesin Subunits Rad21 and SA1/2

(2013) Nenggang Zhang et al.   PLoS One

R Loops: From Transcription Byproducts to Threats to Genome Stability

(2012) Andrés Aguilera et al.   MOLECULAR CELL

Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA

(2011) Andrew R. Dunn et al.   NUCLEIC ACIDS RESEARCH

Cohesinopathies, gene expression, and chromatin organization

(2010) Tania Bose et al.   JOURNAL OF CELL BIOLOGY

Collaborative Dynamic DNA Scanning by Nucleotide Excision Repair Proteins Investigated by Single- Molecule Imaging of Quantum-Dot-Labeled Proteins

(2010) Neil M. Kad et al.   MOLECULAR CELL

Cohesin: Its Roles and Mechanisms

(2009) Kim Nasmyth et al.   Annual Review of Genetics

Sister Chromatid Cohesion: A Simple Concept with a Complex Reality

(2008) Itay Onn et al.   Annual Review of Cell and Developmental Biology

Functional Characterization and Atomic Force Microscopy of a DNA Repair Protein Conjugated to a Quantum Dot

(2008) Hong Wang et al.   NANO LETTERS