Function-Oriented Synthesis: How to Design Simplified Analogues of Antibacterial Nucleoside Natural Products?

Synthesis of isoxazolidine-containing uridine derivatives as caprazamycin analogues

(2015) Mayumi Yamaguchi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Carbacaprazamycins: Chemically Stable Analogues of the Caprazamycin Nucleoside Antibiotics

(2015) Satoshi Ichikawa et al.   ACS Infectious Diseases

Function-Oriented Synthesis of Liponucleoside Antibiotics

(2014) Tetsuya Tanino et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Novel semisynthetic antibiotics from caprazamycins A–G: caprazene derivatives and their antibacterial activity

(2013) Yoshiaki Takahashi et al.   JOURNAL OF ANTIBIOTICS

Inhibition of the First Step in Synthesis of the Mycobacterial Cell Wall Core, Catalyzed by the GlcNAc-1-phosphate Transferase WecA, by the Novel Caprazamycin Derivative CPZEN-45

(2013) Yoshimasa Ishizaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of MraY, an Essential Membrane Enzyme for Bacterial Cell Wall Synthesis

(2013) B. C. Chung et al.   SCIENCE

Multicomponent Assembly Processes for the Synthesis of Diverse Yohimbine and Corynanthe Alkaloid Analogues

(2013) Brett A. Granger et al.   ACS Combinatorial Science

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Multicomponent Assembly Strategies for the Synthesis of Diverse Tetrahydroisoquinoline Scaffolds

(2011) Brett A. Granger et al.   ORGANIC LETTERS

Diversity oriented synthesis: concise entry to novel derivatives of Yohimbine and Corynanthe alkaloids

(2011) Zhiqian Wang et al.   TETRAHEDRON LETTERS

Libraries of 2,3,4,6,7,11b-Hexahydro-1H-pyrido[2,1-a]isoquinolin-2-amine Derivatives via a Multicomponent Assembly Process/1,3-Dipolar Cycloaddition Strategy

(2011) Brett A. Granger et al.   ACS Combinatorial Science

Function-Oriented Synthesis of Simplified Caprazamycins: Discovery of Oxazolidine-Containing Uridine Derivatives as Antibacterial Agents against Drug-Resistant Bacteria

(2010) Kensuke Ii et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimicrobial nucleoside antibiotics targeting cell wall assembly: Recent advances in structure–function studies and nucleoside biosynthesis

(2009) Michael Winn et al.   NATURAL PRODUCT REPORTS

Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy

(2009) Takuya Uchida et al.   ORGANIC LETTERS

Active Site Mapping of MraY, a Member of the Polyprenyl-phosphateN-Acetylhexosamine 1-Phosphate Transferase Superfamily, Catalyzing the First Membrane Step of Peptidoglycan Biosynthesis†

(2008) Bayan Al-Dabbagh et al.   BIOCHEMISTRY

Structure–activity relationship of truncated analogs of caprazamycins as potential anti-tuberculosis agents

(2008) Shinpei Hirano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Physicochemical Properties of Antibacterial Compounds: Implications for Drug Discovery

(2008) Rosemarie O’Shea et al.   JOURNAL OF MEDICINAL CHEMISTRY

Function-Oriented Synthesis, Step Economy, and Drug Design

(2007) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH

Design and synthesis of diketopiperazine and acyclic analogs related to the caprazamycins and liposidomycins as potential antibacterial agents

(2007) Shinpei Hirano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of Caprazamycin Analogues and Their Structure−Activity Relationship for Antibacterial Activity

(2007) Shinpei Hirano et al.   JOURNAL OF ORGANIC CHEMISTRY