Pharmacologic inhibition of lysine-specific demethylase 1 as a therapeutic and immune-sensitization strategy in pediatric high-grade glioma
出版年份 2020 全文链接
标题
Pharmacologic inhibition of lysine-specific demethylase 1 as a therapeutic and immune-sensitization strategy in pediatric high-grade glioma
作者
关键词
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出版物
NEURO-ONCOLOGY
Volume -, Issue -, Pages -
出版商
Oxford University Press (OUP)
发表日期
2020-03-10
DOI
10.1093/neuonc/noaa058
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma
- (2019) Catherine Lee et al. Nature Communications
- Chemoprobe-based assays of histone lysine demethylase 1A target occupation enable in vivo pharmacokinetics and -dynamics studies of KDM1A inhibitors
- (2019) Cristina Mascaró et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HGG-13. DETERMINING REGIONAL DIFFERENCES IN HIGH-GRADE GLIOMA VASCULATURE PHENOTYPE
- (2019) Xin Wei et al. NEURO-ONCOLOGY
- Towards Immunotherapy for Pediatric Brain Tumors
- (2019) Stacie Shiqi Wang et al. TRENDS IN IMMUNOLOGY
- Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201
- (2019) Andrew S. Chi et al. JOURNAL OF NEURO-ONCOLOGY
- LSD1 inhibition exerts its antileukemic effect by recommissioning PU.1- and C/EBPα-dependent enhancers in AML
- (2018) Monica Cusan et al. BLOOD
- Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial
- (2018) Alan Mackay et al. CANCER CELL
- ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
- (2018) Tamara Maes et al. CANCER CELL
- LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
- (2018) Wanqiang Sheng et al. CELL
- Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment
- (2018) Jessica Wagner et al. JOURNAL OF CLINICAL INVESTIGATION
- DIPG-22. A PHASE 1 TRIAL OF THE HISTONE DEACETYLASE INHIBITOR PANOBINOSTAT IN PEDIATRIC PATIENTS WITH RECURRENT OR REFRACTORY DIFFUSE INTRINSIC PONTINE GLIOMA: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY
- (2018) Tabitha Cooney et al. NEURO-ONCOLOGY
- Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy
- (2018) Yangjin Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reversible LSD1 inhibition with HCI-2509 induces the p53 gene expression signature and disrupts the MYCN signature in high-risk neuroblastoma cells
- (2018) Sumati Gupta et al. Oncotarget
- Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia
- (2018) Alba Maiques-Diaz et al. Cell Reports
- Assessment of new HDAC inhibitors for immunotherapy of malignant pleural mesothelioma
- (2018) Douae Bensaid et al. Clinical Epigenetics
- Glioblastoma Stem-Like Cells Are More Susceptible Than Differentiated Cells to Natural Killer Cell Lysis Mediated Through Killer Immunoglobulin-Like Receptors–Human Leukocyte Antigen Ligand Mismatch and Activation Receptor–Ligand Interactions
- (2018) Heleen Neeltje Haspels et al. Frontiers in Immunology
- Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma
- (2018) Carter M. Suryadevara et al. OncoImmunology
- Survival gain in glioblastoma patients treated with dendritic cell immunotherapy is associated with increased NK but not CD8+ T cell activation in the presence of adjuvant temozolomide
- (2018) Serena Pellegatta et al. OncoImmunology
- DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report
- (2018) Sonia Tejada et al. Frontiers in Oncology
- Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: Implications for development of immunotherapy
- (2018) Nicole A P Lieberman et al. NEURO-ONCOLOGY
- Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade
- (2018) Ye Qin et al. ONCOGENE
- T-448, a specific inhibitor of LSD1 enzyme activity, improves learning function without causing thrombocytopenia in mice
- (2018) Satoru Matsuda et al. NEUROPSYCHOPHARMACOLOGY
- Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation
- (2018) Kathleen I. Pishas et al. Oncotarget
- Advances toward LSD1 inhibitors for cancer therapy
- (2017) Xiaoli Fu et al. Future Medicinal Chemistry
- EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas
- (2017) Faizaan Mohammad et al. NATURE MEDICINE
- Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas
- (2017) Andrea Piunti et al. NATURE MEDICINE
- A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
- (2017) Donald M. O’Rourke et al. Science Translational Medicine
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- NKG2D ligand expression in pediatric brain tumors
- (2016) Kristen Haberthur et al. CANCER BIOLOGY & THERAPY
- Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets
- (2016) Tessa Johung et al. Current Neuropharmacology
- EPT-02PHASE I STUDY OF FOURTH VENTRICLE INFUSIONS OF AUTOLOGOUS EX-VIVO EXPANDED NK CELLS IN CHILDREN WITH RECURRENT/REFRACTORY MALIGNANT POSTERIOR FOSSA TUMORS OF THE CENTRAL NERVOUS SYSTEM
- (2016) Soumen Khatua et al. NEURO-ONCOLOGY
- A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC
- (2015) Helai P. Mohammad et al. CANCER CELL
- ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma
- (2015) Congcong Zhang et al. JNCI-Journal of the National Cancer Institute
- Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
- (2015) Catherine S Grasso et al. NATURE MEDICINE
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma
- (2015) Melissa M. Singh et al. NEURO-ONCOLOGY
- ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma
- (2015) Congcong Zhang et al. JNCI-Journal of the National Cancer Institute
- Reversible LSD1 Inhibition Interferes with Global EWS/ETS Transcriptional Activity and Impedes Ewing Sarcoma Tumor Growth
- (2014) S. Sankar et al. CLINICAL CANCER RESEARCH
- Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma
- (2014) Rintaro Hashizume et al. NATURE MEDICINE
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- Inhibition of LSD1 sensitizes glioblastoma cells to histone deacetylase inhibitors
- (2011) M. M. Singh et al. NEURO-ONCOLOGY
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