Illuminating dendritic function with computational models

General Anesthesia Decouples Cortical Pyramidal Neurons

(2020) Mototaka Suzuki et al.   CELL

Breakdown of spatial coding and interneuron synchronization in epileptic mice

(2020) Tristan Shuman et al.   NATURE NEUROSCIENCE

Dendritic action potentials and computation in human layer 2/3 cortical neurons

(2020) Albert Gidon et al.   SCIENCE

Whole-Neuron Synaptic Mapping Reveals Spatially Precise Excitatory/Inhibitory Balance Limiting Dendritic and Somatic Spiking

(2020) Daniel Maxim Iascone et al.   NEURON

Functional Synaptic Architecture of Callosal Inputs in Mouse Primary Visual Cortex

(2019) Kuo-Sheng Lee et al.   NEURON

Tuft dendrites of pyramidal neurons operate as feedback-modulated functional subunits

(2019) Florian Eberhardt et al.   PLoS Computational Biology

Electrical Compartmentalization in Neurons

(2019) Willem A.M. Wybo et al.   Cell Reports

Vasoactive Intestinal Polypeptide-Expressing Interneurons in the Hippocampus Support Goal-Oriented Spatial Learning

(2019) Gergely Farkas Turi et al.   NEURON

Re-evaluating Circuit Mechanisms Underlying Pattern Separation

(2019) N. Alex Cayco-Gajic et al.   NEURON

Amplifying the redistribution of somato-dendritic inhibition by the interplay of three interneuron types

(2019) Loreen Hertäg et al.   PLoS Computational Biology

Kilohertz frame-rate two-photon tomography

(2019) Abbas Kazemipour et al.   NATURE METHODS

Dendritic computations captured by an effective point neuron model

(2019) Songting Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bright and photostable chemigenetic indicators for extended in vivo voltage imaging

(2019) Ahmed S. Abdelfattah et al.   SCIENCE

Engineering a Less Artificial Intelligence

(2019) Fabian H. Sinz et al.   NEURON

Population imaging of neural activity in awake behaving mice

(2019) Kiryl D. Piatkevich et al.   NATURE

A deep learning framework for neuroscience

(2019) Blake A. Richards et al.   NATURE NEUROSCIENCE

Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators

(2019) Alexandra Tzilivaki et al.   Nature Communications

Marked Diversity of Unique Cortical Enhancers Enables Neuron-Specific Tools by Enhancer-Driven Gene Expression

(2018) Stefan Blankvoort et al.   CURRENT BIOLOGY

h-Type Membrane Current Shapes the Local Field Potential from Populations of Pyramidal Neurons

(2018) Torbjørn V. Ness et al.   JOURNAL OF NEUROSCIENCE

Spatially dispersed synapses yield sharply-tuned place cell responses through dendritic spike initiation

(2018) Reshma Basak et al.   JOURNAL OF PHYSIOLOGY-LONDON

Investigating large-scale brain dynamics using field potential recordings: analysis and interpretation

(2018) Bijan Pesaran et al.   NATURE NEUROSCIENCE

Synaptic Integration in Cortical Inhibitory Neuron Dendrites

(2018) Hua Hu et al.   NEUROSCIENCE

Sparse bursts optimize information transmission in a multiplexed neural code

(2018) Richard Naud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Cortical Pyramidal Neurons: From Spines to Spikes via Models

(2018) Guy Eyal et al.   Frontiers in Cellular Neuroscience

Structural absorption by barbule microstructures of super black bird of paradise feathers

(2018) Dakota E. McCoy et al.   Nature Communications

Neuronal gain modulability is determined by dendritic morphology: A computational optogenetic study

(2018) Sarah Jarvis et al.   PLoS Computational Biology

A Mixed-Signal Structured AdEx Neuron for Accelerated Neuromorphic Cores

(2018) Syed Ahmed Aamir et al.   IEEE Transactions on Biomedical Circuits and Systems

Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

(2018) Eszter Boldog et al.   NATURE NEUROSCIENCE

Reply to ‘Can neocortical feedback alter the sign of plasticity?’

(2018) Pieter R. Roelfsema et al.   NATURE REVIEWS NEUROSCIENCE

Dendrite-Specific Amplification of Weak Synaptic Input during Network Activity In Vivo

(2018) Leiron Ferrarese et al.   Cell Reports

Enhanced Dendritic Compartmentalization in Human Cortical Neurons

(2018) Lou Beaulieu-Laroche et al.   CELL

Dendritic sodium spikes endow neurons with inverse firing rate response to correlated synaptic activity

(2018) Tomasz Górski et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition

(2018) Leena E. Williams et al.   NEURON

Global and Multiplexed Dendritic Computations under In Vivo-like Conditions

(2018) Balázs B. Ujfalussy et al.   NEURON

Visual physiology of the layer 4 cortical circuit in silico

(2018) Anton Arkhipov et al.   PLoS Computational Biology

Dendritic mechanisms of hippocampal place field formation

(2018) Mark EJ Sheffield et al.   CURRENT OPINION IN NEUROBIOLOGY

Basal tree complexity shapes functional pathways in the prefrontal cortex

(2017) Athanasia Papoutsi et al.   JOURNAL OF NEUROPHYSIOLOGY

Viewpoints: how the hippocampus contributes to memory, navigation and cognition

(2017) John Lisman et al.   NATURE NEUROSCIENCE

Active dendritic integration as a mechanism for robust and precise grid cell firing

(2017) Christoph Schmidt-Hieber et al.   NATURE NEUROSCIENCE

Dendrites Enable a Robust Mechanism for Neuronal Stimulus Selectivity

(2017) Romain D. Cazé et al.   NEURAL COMPUTATION

Increased Prevalence of Calcium Transients across the Dendritic Arbor during Place Field Formation

(2017) Mark E.J. Sheffield et al.   NEURON

Behavioral time scale synaptic plasticity underlies CA1 place fields

(2017) Katie C. Bittner et al.   SCIENCE

Modeling somatic and dendritic spike mediated plasticity at the single neuron and network level

(2017) Jacopo Bono et al.   Nature Communications

Timed Synaptic Inhibition Shapes NMDA Spikes, Influencing Local Dendritic Processing and Global I/O Properties of Cortical Neurons

(2017) Michael Doron et al.   Cell Reports

Towards deep learning with segregated dendrites

(2017) Jordan Guerguiev et al.   eLife

From Neuron Biophysics to Orientation Selectivity in Electrically Coupled Networks of Neocortical L2/3 Large Basket Cells

(2016) Oren Amsalem et al.   CEREBRAL CORTEX

Dendrites of dentate gyrus granule cells contribute to pattern separation by controlling sparsity

(2016) Spyridon Chavlis et al.   HIPPOCAMPUS

Orientation selectivity and the functional clustering of synaptic inputs in primary visual cortex

(2016) Daniel E Wilson et al.   NATURE NEUROSCIENCE

Mnemonic Functions for Nonlinear Dendritic Integration in Hippocampal Pyramidal Circuits

(2016) Patrick Kaifosh et al.   NEURON

Differential Dendritic Integration of Synaptic Potentials and Calcium in Cerebellar Interneurons

(2016) Alexandra Tran-Van-Minh et al.   NEURON

Structured Dendritic Inhibition Supports Branch-Selective Integration in CA1 Pyramidal Cells

(2016) Erik B. Bloss et al.   NEURON

Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding

(2016) Nathan B. Danielson et al.   NEURON

GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits

(2016) Robin Tremblay et al.   NEURON

Active cortical dendrites modulate perception

(2016) Naoya Takahashi et al.   SCIENCE

Linking Memories across Time via Neuronal and Dendritic Overlaps in Model Neurons with Active Dendrites

(2016) George Kastellakis et al.   Cell Reports

Extending Integrate-and-Fire Model Neurons to Account for the Effects of Weak Electric Fields and Input Filtering Mediated by the Dendrite

(2016) Florian Aspart et al.   PLoS Computational Biology

Inhibition as a Binary Switch for Excitatory Plasticity in Pyramidal Neurons

(2016) Katharina A. Wilmes et al.   PLoS Computational Biology

Interneuronal mechanisms of hippocampal theta oscillations in a full-scale model of the rodent CA1 circuit

(2016) Marianne J Bezaire et al.   eLife

Reconstruction and Simulation of Neocortical Microcircuitry

(2015) Henry Markram et al.   CELL

Dendritic and Axonal Architecture of Individual Pyramidal Neurons across Layers of Adult Human Neocortex

(2015) Hemanth Mohan et al.   CEREBRAL CORTEX

Labelling and optical erasure of synaptic memory traces in the motor cortex

(2015) Akiko Hayashi-Takagi et al.   NATURE

Dendritic integration: 60 years of progress

(2015) Greg J Stuart et al.   NATURE NEUROSCIENCE

Hardware-Amenable Structural Learning for Spike-Based Pattern Classification Using a Simple Model of Active Dendrites

(2015) Shaista Hussain et al.   NEURAL COMPUTATION

Effects of Neural Morphology and Input Distribution on Synaptic Processing by Global and Focal NMDA-Spikes

(2015) Alon Poleg-Polsky   PLoS One

Synaptic clustering within dendrites: An emerging theory of memory formation

(2015) George Kastellakis et al.   PROGRESS IN NEUROBIOLOGY

The 40-year history of modeling active dendrites in cerebellar Purkinje cells: emergence of the first single cell “community model”

(2015) James M. Bower   Frontiers in Computational Neuroscience

A Cortical Circuit for Gain Control by Behavioral State

(2014) Yu Fu et al.   CELL

Dendritic Excitability and Gain Control in Recurrent Cortical Microcircuits

(2014) Etay Hay et al.   CEREBRAL CORTEX

Liquid State Machine With Dendritically Enhanced Readout for Low-Power, Neuromorphic VLSI Implementations

(2014) Subhrajit Roy et al.   IEEE Transactions on Biomedical Circuits and Systems

Automatic parameter estimation of multicompartmental neuron models via minimization of trace error with control adjustment

(2014) Ted Brookings et al.   JOURNAL OF NEUROPHYSIOLOGY

Dendrites Impact the Encoding Capabilities of the Axon

(2014) G. Eyal et al.   JOURNAL OF NEUROSCIENCE

Calcium transient prevalence across the dendritic arbour predicts place field properties

(2014) Mark E. J. Sheffield et al.   NATURE

Selective Memory Generalization by Spatial Patterning of Protein Synthesis

(2014) Cian O’Donnell et al.   NEURON

Learning by the Dendritic Prediction of Somatic Spiking

(2014) Robert Urbanczik et al.   NEURON

Structured Synaptic Connectivity between Hippocampal Regions

(2014) Shaul Druckmann et al.   NEURON

Dendritic Spikes Induce Ripples in Parvalbumin Interneurons during Hippocampal Sharp Waves

(2014) Balázs Chiovini et al.   NEURON

An Augmented Two-Layer Model Captures Nonlinear Analog Spatial Integration Effects in Pyramidal Neuron Dendrites

(2014) Monika P. Jadi et al.   PROCEEDINGS OF THE IEEE

Activity-dependent dendritic spine neck changes are correlated with synaptic strength

(2014) R. Araya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-range and local circuits for top-down modulation of visual cortex processing

(2014) S. Zhang et al.   SCIENCE

A simulation study on the effects of dendritic morphology on layer V prefrontal pyramidal cell firing behavior

(2014) Maria Psarrou et al.   Frontiers in Cellular Neuroscience

Modulatory effects of inhibition on persistent activity in a cortical microcircuit model

(2014) Xanthippi Konstantoudaki et al.   Frontiers in Neural Circuits

Spike-timing prediction in cortical neurons with active dendrites

(2014) Richard Naud et al.   Frontiers in Computational Neuroscience

Glutamate-Bound NMDARs Arising from In Vivo-like Network Activity Extend Spatio-temporal Integration in a L5 Cortical Pyramidal Cell Model

(2014) Matteo Farinella et al.   PLoS Computational Biology

Dendritic Nonlinearities Reduce Network Size Requirements and Mediate ON and OFF States of Persistent Activity in a PFC Microcircuit Model

(2014) Athanasia Papoutsi et al.   PLoS Computational Biology

Functional Impact of Dendritic Branch-Point Morphology

(2013) M. Ferrante et al.   JOURNAL OF NEUROSCIENCE

Dendritic spikes enhance stimulus selectivity in cortical neurons in vivo

(2013) Spencer L. Smith et al.   NATURE

Cortical interneurons that specialize in disinhibitory control

(2013) Hyun-Jae Pi et al.   NATURE

Cortical connectivity and sensory coding

(2013) Kenneth D. Harris et al.   NATURE

Inhibition of inhibition in visual cortex: the logic of connections between molecularly distinct interneurons

(2013) Carsten K Pfeffer et al.   NATURE NEUROSCIENCE

Linear transformation of thalamocortical input by intracortical excitation

(2013) Ya-tang Li et al.   NATURE NEUROSCIENCE

A disinhibitory circuit mediates motor integration in the somatosensory cortex

(2013) Soohyun Lee et al.   NATURE NEUROSCIENCE

NMDA Receptors Subserve Persistent Neuronal Firing during Working Memory in Dorsolateral Prefrontal Cortex

(2013) Min Wang et al.   NEURON

A Biophysically Detailed Model of Neocortical Local Field Potentials Predicts the Critical Role of Active Membrane Currents

(2013) Michael W. Reimann et al.   NEURON

Correction: Structural Characterization of the Complex of SecB and Metallothionein-Labeled proOmpA by Cryo-Electron Microscopy

(2013) Qiang Zhou et al.   PLoS One

Mechanisms underlying subunit independence in pyramidal neuron dendrites

(2013) B. F. Behabadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional mapping of microcircuit correlation structure

(2013) R. James Cotton et al.   Frontiers in Neural Circuits

Nonlinear dendritic integration of sensory and motor input during an active sensing task

(2012) Ning-long Xu et al.   NATURE

Repetitive motor learning induces coordinated formation of clustered dendritic spines in vivo

(2012) Min Fu et al.   NATURE

Nonlinear dendritic processing determines angular tuning of barrel cortex neurons in vivo

(2012) Maria Lavzin et al.   NATURE

From circuits to behavior: a bridge too far?

(2012) Matteo Carandini   NATURE NEUROSCIENCE

Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons

(2012) Sooyun Kim et al.   NATURE NEUROSCIENCE

Regulation of neuronal input transformations by tunable dendritic inhibition

(2012) Matthew Lovett-Barron et al.   NATURE NEUROSCIENCE

The origin of extracellular fields and currents — EEG, ECoG, LFP and spikes

(2012) György Buzsáki et al.   NATURE REVIEWS NEUROSCIENCE

Thin Dendrites of Cerebellar Interneurons Confer Sublinear Synaptic Integration and a Gradient of Short-Term Plasticity

(2012) Therese Abrahamsson et al.   NEURON

Principles Governing the Operation of Synaptic Inhibition in Dendrites

(2012) Albert Gidon et al.   NEURON

Imaging Calcium in Neurons

(2012) Christine Grienberger et al.   NEURON

Know Your Current Ih: Interaction with a Shunting Current Explains the Puzzling Effects of Its Pharmacological or Pathological Modulations

(2012) Michele Migliore et al.   PLoS One

Locally Synchronized Synaptic Inputs

(2012) N. Takahashi et al.   SCIENCE

Hippocampal Place Fields Emerge upon Single-Cell Manipulation of Excitability During Behavior

(2012) D. Lee et al.   SCIENCE

A cellular mechanism for cortical associations: an organizing principle for the cerebral cortex

(2012) Matthew Larkum   TRENDS IN NEUROSCIENCES

Location-Dependent Effects of Inhibition on Local Spiking in Pyramidal Neuron Dendrites

(2012) Monika Jadi et al.   PLoS Computational Biology

Location-Dependent Excitatory Synaptic Interactions in Pyramidal Neuron Dendrites

(2012) Bardia F. Behabadi et al.   PLoS Computational Biology

Predictive Features of Persistent Activity Emergence in Regular Spiking and Intrinsic Bursting Model Neurons

(2012) Kyriaki Sidiropoulou et al.   PLoS Computational Biology

Branch-Specific Plasticity Enables Self-Organization of Nonlinear Computation in Single Neurons

(2011) R. Legenstein et al.   JOURNAL OF NEUROSCIENCE

mGRASP enables mapping mammalian synaptic connectivity with light microscopy

(2011) Jinhyun Kim et al.   NATURE METHODS

Synaptic Integration Gradients in Single Cortical Pyramidal Cell Dendrites

(2011) Tiago Branco et al.   NEURON

Modeling the Spatial Reach of the LFP

(2011) Henrik Lindén et al.   NEURON

Ih-mediated depolarization enhances the temporal precision of neuronal integration

(2011) Ivan Pavlov et al.   Nature Communications

Effective Stimuli for Constructing Reliable Neuron Models

(2011) Shaul Druckmann et al.   PLoS Computational Biology

The single dendritic branch as a fundamental functional unit in the nervous system

(2010) Tiago Branco et al.   CURRENT OPINION IN NEUROBIOLOGY

Local Control of Postinhibitory Rebound Spiking in CA1 Pyramidal Neuron Dendrites

(2010) G. A. Ascoli et al.   JOURNAL OF NEUROSCIENCE

Dendritic organization of sensory input to cortical neurons in vivo

(2010) Hongbo Jia et al.   NATURE

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

Quantitative prediction of intermittent high-frequency oscillations in neural networks with supralinear dendritic interactions

(2010) R.-M. Memmesheimer   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Discrimination of Temporal Input Sequences in Cortical Neurons

(2010) T. Branco et al.   SCIENCE

Stochastic Ion Channel Gating in Dendritic Neurons: Morphology Dependence and Probabilistic Synaptic Activation of Dendritic Spikes

(2010) Robert C. Cannon et al.   PLoS Computational Biology

One Rule to Grow Them All: A General Theory of Neuronal Branching and Its Practical Application

(2010) Hermann Cuntz et al.   PLoS Computational Biology

Dendritic Excitability and Neuronal Morphology as Determinants of Synaptic Efficacy

(2009) Alexander O. Komendantov et al.   JOURNAL OF NEUROPHYSIOLOGY

Dendritic encoding of sensory stimuli controlled by deep cortical interneurons

(2009) Masanori Murayama et al.   NATURE

Capacity-Enhancing Synaptic Learning Rules in a Medial Temporal Lobe Online Learning Model

(2009) Xundong E. Wu et al.   NEURON

Synapse Distribution Suggests a Two-Stage Model of Dendritic Integration in CA1 Pyramidal Neurons

(2009) Yael Katz et al.   NEURON

An arithmetic rule for spatial summation of excitatory and inhibitory inputs in pyramidal neurons

(2009) J. Hao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Integration in Tuft Dendrites of Layer 5 Pyramidal Neurons: A New Unifying Principle

(2009) M. E. Larkum et al.   SCIENCE

Synaptic clustering by dendritic signalling mechanisms

(2008) Matthew E Larkum et al.   CURRENT OPINION IN NEUROBIOLOGY

Single neuron binding properties and the magical number 7

(2008) Michele Migliore et al.   HIPPOCAMPUS

Spatiotemporally Graded NMDA Spike/Plateau Potentials in Basal Dendrites of Neocortical Pyramidal Neurons

(2008) Guy Major et al.   JOURNAL OF NEUROPHYSIOLOGY

Learning Drives Differential Clustering of Axodendritic Contacts in the Barn Owl Auditory System

(2008) T. J. McBride et al.   JOURNAL OF NEUROSCIENCE

Compartmentalized dendritic plasticity and input feature storage in neurons

(2008) Attila Losonczy et al.   NATURE

Dendritic Excitability and Synaptic Plasticity

(2008) P. Jesper Sjöström et al.   PHYSIOLOGICAL REVIEWS