标题
Evaluating and improving heritability models using summary statistics
作者
关键词
-
出版物
NATURE GENETICS
Volume 52, Issue 4, Pages 458-462
出版商
Springer Science and Business Media LLC
发表日期
2020-03-24
DOI
10.1038/s41588-020-0600-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Reconciling S-LDSC and LDAK functional enrichment estimates
- (2019) Steven Gazal et al. NATURE GENETICS
- Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture
- (2019) Kangcheng Hou et al. NATURE GENETICS
- Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits
- (2018) Luke M. Evans et al. NATURE GENETICS
- Signatures of negative selection in the genetic architecture of human complex traits
- (2018) Jian Zeng et al. NATURE GENETICS
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- SumHer better estimates the SNP heritability of complex traits from summary statistics
- (2018) Doug Speed et al. NATURE GENETICS
- Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection
- (2017) Steven Gazal et al. NATURE GENETICS
- Concepts, estimation and interpretation of SNP-based heritability
- (2017) Jian Yang et al. NATURE GENETICS
- Reevaluation of SNP heritability in complex human traits
- (2017) Doug Speed et al. NATURE GENETICS
- LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
- (2016) Jie Zheng et al. BIOINFORMATICS
- Genome-wide association study identifies 74 loci associated with educational attainment
- (2016) Aysu Okbay et al. NATURE
- Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses
- (2016) Aysu Okbay et al. NATURE GENETICS
- Dissecting the genetics of complex traits using summary association statistics
- (2016) Bogdan Pasaniuc et al. NATURE REVIEWS GENETICS
- Genetic studies of body mass index yield new insights for obesity biology
- (2015) Adam E. Locke et al. NATURE
- Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
- (2015) Hou‐Feng Zheng et al. NATURE
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
- (2015) Jimmy Z Liu et al. NATURE GENETICS
- Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
- (2015) Jian Yang et al. NATURE GENETICS
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
- (2015) Felix R Day et al. NATURE GENETICS
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases
- (2014) Alexander Gusev et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Describing the genetic architecture of epilepsy through heritability analysis
- (2014) Doug Speed et al. BRAIN
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
- (2014) John R. B. Perry et al. NATURE
- Defining the role of common variation in the genomic and biological architecture of adult human height
- (2014) Andrew R Wood et al. NATURE GENETICS
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- Improved Heritability Estimation from Genome-wide SNPs
- (2012) Doug Speed et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
- (2011) Heribert Schunkert et al. NATURE GENETICS
- GCTA: A Tool for Genome-wide Complex Trait Analysis
- (2010) Jian Yang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- Genome-wide meta-analyses identify multiple loci associated with smoking behavior
- (2010) NATURE GENETICS
- Common SNPs explain a large proportion of the heritability for human height
- (2010) Jian Yang et al. NATURE GENETICS
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