Viral contamination in biologic manufacture and implications for emerging therapies

Use of a new RNA next generation sequencing approach for the specific detection of virus infection in cells

(2019) Audrey Brussel et al.   BIOLOGICALS

Erratum: The long view on sequencing

(2018)   NATURE BIOTECHNOLOGY

Evaluating ultraviolet sensitivity of adventitious agents in biopharmaceutical manufacturing

(2017) Sarah M. Meunier et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Vesivirus 2117: Cell line infectivity range and effectiveness of amplification of a potential adventitious agent in cell culture used for biological production

(2016) Mark Plavsic et al.   BIOLOGICALS

Design of serum-free medium for suspension culture of CHO cells on the basis of general commercial media

(2014) Hideo Miki et al.   CYTOTECHNOLOGY

Biopharmaceutical benchmarks 2014

(2014) Gary Walsh   NATURE BIOTECHNOLOGY

Systematic evaluation of in vitro and in vivo adventitious virus assays for the detection of viral contamination of cell banks and biological products

(2014) James Gombold et al.   VACCINE

History of gene therapy

(2013) Thomas Wirth et al.   GENE

Identification and quantitation of vesivirus 2117 particles in bioreactor fluids from infected Chinese hamster ovary cell cultures

(2012) Yongchang Qiu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Effectiveness of mouse minute virus inactivation by high temperature short time treatment technology: A statistical assessment

(2011) Marie Murphy et al.   BIOLOGICALS

Peak serum: implications of serum supply for cell therapy manufacturing

(2011) David A Brindley et al.   Regenerative Medicine

Molecular and infectivity studies of porcine circovirus in vaccines

(2011) Shasta D. McClenahan et al.   VACCINE

Viral Nucleic Acids in Live-Attenuated Vaccines: Detection of Minority Variants and an Adventitious Virus

(2010) J. G. Victoria et al.   JOURNAL OF VIROLOGY

As Genzyme flounders, competitors and activist investors swoop in

(2010) Malorye Allison   NATURE BIOTECHNOLOGY

Analysis of porcine circovirus type 1 detected in Rotarix vaccine

(2010) Sally A. Baylis et al.   VACCINE

Emerging trends in plasma-free manufacturing of recombinant protein therapeutics expressed in mammalian cells

(2009) Leopold Grillberger et al.   Biotechnology Journal

Susceptibility of mouse minute virus to inactivation by heat in two cell culture media types

(2009) Marc Schleh et al.   BIOTECHNOLOGY PROGRESS

Virus stalls Genzyme plant

(2009) Victor Bethencourt   NATURE BIOTECHNOLOGY