Integrating genomic features for non-invasive early lung cancer detection

Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial

(2020) Harry J. de Koning et al.   NEW ENGLAND JOURNAL OF MEDICINE

1PPIWI proteins play oncogenic functions in pancreatic cancer

(2019) W Li et al.   ANNALS OF ONCOLOGY

Genome-wide cell-free DNA fragmentation in patients with cancer

(2019) Stephen Cristiano et al.   NATURE

Dynamic Risk Profiling Using Serial Tumor Biomarkers for Personalized Outcome Prediction

(2019) David M. Kurtz et al.   CELL

High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants

(2019) Pedram Razavi et al.   NATURE MEDICINE

Comprehensive Characterization of Cancer Driver Genes and Mutations

(2018) Matthew H. Bailey et al.   CELL

Detection and localization of surgically resectable cancers with a multi-analyte blood test

(2018) Joshua D. Cohen et al.   SCIENCE

Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors

(2018) Ryan N. Ptashkin et al.   JAMA Oncology

Sensitive tumour detection and classification using plasma cell-free DNA methylomes

(2018) Shu Yi Shen et al.   NATURE

Enhanced detection of circulating tumor DNA by fragment size analysis

(2018) Florent Mouliere et al.   Science Translational Medicine

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

(2017) Christopher Abbosh et al.   NATURE

Direct detection of early-stage cancers using circulating tumor DNA

(2017) Jillian Phallen et al.   Science Translational Medicine

Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling

(2017) Aadel A. Chaudhuri et al.   Cancer Discovery

Lung Cancer Screening With Low-Dose Computed Tomography in the United States—2010 to 2015

(2017) Ahmedin Jemal et al.   JAMA Oncology

Integrated digital error suppression for improved detection of circulating tumor DNA

(2016) Aaron M Newman et al.   NATURE BIOTECHNOLOGY

Somatic TP53 Mutations in the Era of Genome Sequencing

(2016) Pierre Hainaut et al.   Cold Spring Harbor Perspectives in Medicine

Performance of Lung-RADS in the National Lung Screening Trial

(2015) Paul F. Pinsky et al.   ANNALS OF INTERNAL MEDICINE

Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

(2015) D. P. Steensma et al.   BLOOD

Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients

(2015) Peiyong Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Annual number of lung cancer deaths potentially avertable by screening in the United States

(2013) Jiemin Ma et al.   CANCER

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Results of Initial Low-Dose Computed Tomographic Screening for Lung Cancer

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs

(2012) Christopher T. Saunders et al.   BIOINFORMATICS

Use of Lung Cancer Screening Tests in the United States: Results from the 2010 National Health Interview Survey

(2012) V. P. Doria-Rose et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

Absolute quantification of somatic DNA alterations in human cancer

(2012) Scott L Carter et al.   NATURE BIOTECHNOLOGY

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma

(2011) William D. Travis et al.   Journal of Thoracic Oncology

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

(2011) Craig H Mermel et al.   GENOME BIOLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS