Neoplastic fibrocytes play an essential role in bone marrow fibrosis in Jak2V617F-induced primary myelofibrosis mice

Cytokine production in myelofibrosis exhibits differential responsiveness to JAK-STAT, MAP kinase, and NFκB signaling

(2019) Daniel A. C. Fisher et al.   LEUKEMIA

IL-1 Family Cytokine Regulation of Vascular Permeability and Angiogenesis

(2019) Erin Fahey et al.   Frontiers in Immunology

Primary myelofibrosis marrow-derived CD14+/CD34- monocytes induce myelofibrosis-like phenotype in immunodeficient mice and give rise to megakaryocytes

(2019) Taghi Manshouri et al.   PLoS One

IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse

(2018) Takatsugu Oike et al.   Scientific Reports

Myeloproliferative leukemia protein activation directly induces fibrocyte differentiation to cause myelofibrosis

(2017) T Maekawa et al.   LEUKEMIA

Generation of a transgenic mouse line for conditional expression of human IL-6

(2016) Taiki Mori et al.   EXPERIMENTAL ANIMALS

Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies

(2016) A. A. Zahr et al.   HAEMATOLOGICA

Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis

(2016) Srdan Verstovsek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Which patients with myelofibrosis should receive ruxolitinib therapy? ELN-SIE evidence-based recommendations

(2016) M Marchetti et al.   LEUKEMIA

Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies

(2016) A. A. Zahr et al.   HAEMATOLOGICA

Interleukin-6 Stimulates Defective Angiogenesis

(2015) G. Gopinathan et al.   CANCER RESEARCH

Distinct clustering of symptomatic burden among myeloproliferative neoplasm patients: retrospective assessment in 1470 patients

(2014) H. L. Geyer et al.   BLOOD

Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis

(2014) R. Rampal et al.   BLOOD

Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator

(2014) T. Kameda et al.   BLOOD

An Interleukin-1 Beta-Encoding Retrovirus Exhibits Enhanced ReplicationIn Vivo

(2014) Edward P. Browne   JOURNAL OF VIROLOGY

Fibrocytes develop outside the kidney but contribute to renal fibrosis in a mouse model

(2013) Barbara Reich et al.   KIDNEY INTERNATIONAL

A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis

(2012) Srdan Verstovsek et al.   NEW ENGLAND JOURNAL OF MEDICINE

JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis

(2012) Claire Harrison et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Markers that Distinguish Monocyte-Derived Fibrocytes from Monocytes, Macrophages, and Fibroblasts

(2009) Darrell Pilling et al.   PLoS One