☆ 4.3 Letter

A severe-type COVID-19 case with prolonged virus shedding

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION (2020)

期刊

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

卷 119, 期 10, 页码 1555-1557

出版社

ELSEVIER TAIWAN

DOI: 10.1016/j.jfma.2020.05.004

关键词

-

类别

Medicine, General & Internal

资金

National Natural Science Foundation of China [81770002]
Science and Technology Program of Changsha, China [kq1901120]
National Key Clinical Specialty Discipline Construction Program of China

向作者/读者索取更多资源

Protocol

Reagent

作者

我是这篇论文的作者

点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.3

评分不足

次要评分

新颖性

-

重要性

-

科学严谨性

-

评价这篇论文

推荐

Article Clinical Neurology

Prolonged Unconsciousness Following Severe COVID-19

Wilson F. Abdo, Catharina Broerse, Bart P. Grady, Agnes A. A. C. M. Wertenbroek, Onno Vijlbrief, Marc P. Buise, Menno Beukema, Mark van der Kuil, Anil M. Tuladhar, Frederick J. A. Meijer, Johannes G. van der Hoeven

Summary: In this case series, patients with severe respiratory failure due to COVID-19 experienced prolonged but reversible unconsciousness after cessation of sedatives. Despite the initial comatose state, all cases eventually showed signs of awakening after a period of time, highlighting the importance of cautious prognostication in such patients.

NEUROLOGY (2021)

添加到收藏夹

Article Immunology

Viral Haplotypes in COVID-19 Patients Associated With Prolonged Viral Shedding

Yingping Wu, Shufa Zheng, Tian Liu, Xueke Liu, Huina Tang, Yutong He, Wei Xu, Lele Li, Wenxu Yu, Ke Xing, Xiaoping Xia

Summary: Whole-genome sequencing analysis of three COVID-19-confirmed patients revealed that the haplotype diversity of SARS-CoV-2 may lead to viral adaptation for persistent shedding in multiple recurrences, impacting the clinical management of COVID-19 patients with long-term hospitalization or cases of recurrence.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

添加到收藏夹

Article Cell Biology

Enhanced inflammation and suppressed adaptive immunity in COVID-19 with prolonged RNA shedding

Xiaohua Tang, Rui Sun, Weigang Ge, Tingting Mao, Liujia Qian, Chongquan Huang, Zhouyang Kang, Qi Xiao, Meng Luo, Qiushi Zhang, Sainan Li, Hao Chen, Wei Liu, Bingjie Wang, Shufei Li, Xiaoling Lin, Xueqin Xu, Huanzheng Li, Lianpeng Wu, Jianyi Dai, Huanhuan Gao, Lu Li, Tian Lu, Xiao Liang, Xue Cai, Guan Ruan, Fei Xu, Yan Li, Yi Zhu, Ziqing Kong, Jianping Huang, Tiannan Guo

Summary: This study revealed enhanced inflammation and suppressed adaptive immunity in COVID-19 patients with prolonged viral RNA shedding, and proposed a multi-omic classifier for predicting viral RNA shedding.

CELL DISCOVERY (2022)

添加到收藏夹

Article Oncology

Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses

Olga Lyudovyk, Justin Y. Kim, David Qualls, Madeline A. Hwee, Ya-Hui Lin, Sawsan R. Boutemine, Yuval Elhanati, Alexander Solovyov, Melanie Douglas, Eunise Chen, N. Esther Babady, Lakshmi Ramanathan, Pallavi Vedantam, Chaitanya Bandlamudi, Sigrid Gouma, Philip Wong, Scott E. Hensley, Benjamin Greenbaurn, Alexander C. Huang, Santosha A. Vardhana

Summary: This study analyzes the immune responses of 103 patients with prior COVID-19 infection and finds that delayed viral clearance is associated with antibody loss and increased T cell responses. CD8(+) T cell differentiation and diverse COVID-specific T cell receptor (TCR) repertoire indicate prolonged disease. Conversely, a CD4(+) T cell dominant immunophenotype promotes effective viral clearance and T cell memory development.

CANCER CELL (2022)

添加到收藏夹

Article Virology

Duration of SARS-CoV-2 RNA shedding and factors associated with prolonged viral shedding in patients with COVID-19

Tong-Zeng Li, Zhen-Huan Cao, Yu Chen, Miao-Tian Cai, Long-Yu Zhang, Hui Xu, Jia-Ying Zhang, Chun-Hua Ma, Yang Liu, Li-Juan Gao, Zhong-Hui Duan, Dan-Lei Mou, Lian-Chun Liang

Summary: This study found that corticosteroid treatment, fever (temperature>38.5 degrees C), and longer time from onset to hospitalization were associated with prolonged viral shedding duration in COVID-19 patients.

JOURNAL OF MEDICAL VIROLOGY (2021)

添加到收藏夹

Article Immunology

Prolonged viral shedding and antibody persistence in patients with COVID-19

Fatemeh Fotouhi, Mostafa Salehi-Vaziri, Behrokh Farahmand, Ehsan Mostafavi, Mohammad Hassan Pouriayevali, Tahmineh Jalali, Vahideh Mazaheri, Mona Sadat Larijani, Mahsa Tavakoli, Azita Eshratkhah Mohammadnejad, Neda Afzali, Afsaneh Zokaei, SeyedeAtefe Hosseini, Mohamad Mahdi Mortazavipour, FaridehNiknam Oskouei, Amitis Ramezani

Summary: The study investigated the viral shedding duration and antibody development against SARS-CoV-2 in 255 COVID-19 suspected individuals, finding a median viral shedding duration of 34.16 days and presence of IgG in 84% of patients after 150 days. This suggests that a 14-day isolation period may not be sufficient for proper control, and the persistence of IgG in a majority of patients for nearly 6 months brings hope for vaccine effectiveness and application.

MICROBES AND INFECTION (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)

Jeroen J. A. van Kampen, David A. M. C. van de Vijver, Pieter L. A. Fraaij, Bart L. Haagmans, Mart M. Lamers, Nisreen Okba, Johannes P. C. van den Akker, Henrik Endeman, Diederik A. M. P. J. Gommers, Jan J. Cornelissen, Rogier A. S. Hoek, Menno M. van der Eerden, Dennis A. Hesselink, Herold J. Metselaar, Annelies Verbon, Jurriaan E. M. de Steenwinkel, Georgina I. Aron, Eric C. M. van Gorp, Sander van Boheemen, Jolanda C. Voermans, Charles A. B. Boucher, Richard Molenkamp, Marion P. G. Koopmans, Corine Geurtsvankessel, Annemiek A. van der Eijk

Summary: The study found that the median duration of shedding infectious virus in COVID-19 patients is 8 days, dropping below 5% after 15.2 days post onset of symptoms. High viral loads are associated with infectious SARS-CoV-2 isolation, while high serum neutralizing antibody titres are associated with non-infectious SARS-CoV-2.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Medicine, General & Internal

Case Report: Prolonged VV-ECMO (111 Days) Support in a Patient With Severe COVID-19

Zhiheng Xu, Yonghao Xu, Dongdong Liu, Xuesong Liu, Liang Zhou, Yongbo Huang, Yimin Li, Xiaoqing Liu

Summary: This case report demonstrates the successful use of prolonged VV-ECMO (111 days) in a 61-year-old man with severe COVID-19, providing evidence for the efficacy of prolonged VV-ECMO as supportive care in patients with severe COVID-19.

FRONTIERS IN MEDICINE (2021)

添加到收藏夹

Article Virology

Prolonged fecal shedding of SARS-CoV-2 in a young immunocompetent COVID-19 patient: A case report and literature overview

Fang Xiao, Peiqi Wan, Qiuling Wei, Guiyang Wei, Yanhong Yu

Summary: This article reports a case of SARS-CoV-2 infection in a young immunocompetent patient, with viral RNA detected for 71 days. Despite the patient's recovery and lack of clinical symptoms, viral RNA continued to be detected in stool samples.

JOURNAL OF MEDICAL VIROLOGY (2022)

添加到收藏夹

Article Multidisciplinary Sciences

A prenylated dsRNA sensor protects against severe COVID-19

Arthur Wickenhagen, Elena Sugrue, Spyros Lytras, Srikeerthana Kuchi, Marko Noerenberg, Matthew L. Turnbull, Colin Loney, Vanessa Herder, Jay Allan, Innes Jarmson, Natalia Cameron-Ruiz, Margus Varjak, Rute M. Pinto, Jeffrey Y. Lee, Louisa Iselin, Natasha Palmalux, Douglas G. Stewart, Simon Swingler, Edward J. D. Greenwood, Thomas W. M. Crozier, Quan Gu, Emma L. Davies, Sara Clohisey, Bo Wang, Fabio Trindade Maranhao Costa, Monique Freire Santana, Luiz Carlos de Lima Ferreira, Lee Murphy, Angie Fawkes, Alison Meynert, Graeme Grimes, Joao Luiz Da Silva Filho, Matthias Marti, Joseph Hughes, Richard J. Stanton, Eddie C. Y. Wang, Antonia Ho, Ilan Davis, Ruth F. Jarrett, Alfredo Castello, David L. Robertson, Malcolm G. Semple, Peter J. M. Openshaw, Massimo Palmarini, Paul J. Lehner, J. Kenneth Baillie, Suzannah J. Rihn, Sam J. Wilson

Summary: Inherited genetic factors can influence the severity of COVID-19, with intracellular antiviral defenses, particularly OAS1 through ribonuclease L, playing a significant role in inhibiting SARS-CoV-2. The expression of prenylated OAS1 may be associated with protection from severe COVID-19 in hospitalized patients.

SCIENCE (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Treatment of severe COVID-19 with convalescent plasma in Bronx, NYC

Hyun ah Yoon, Rachel Bartash, Inessa Gendlina, Johanna Rivera, Antonio Nakouzi, Robert H. Bortz, Ariel S. Wirchnianski, Monika Paroder, Karen Fehn, Leana Serrano-Rahman, Rachelle Babb, Uzma N. Sarwar, Denise Haslwanter, Ethan Laudermilch, Catalina Florez, M. Eugenia Dieterle, Rohit K. Jangra, J. Maximilian Fels, Karen Tong, Margarette C. Mariano, Olivia Vergnolle, George Georgiev, Natalia G. Herrera, Ryan J. Malonis, Jose A. Quiroz, Nicholas C. Morano, Gregory J. Krause, Joseph M. Sweeney, Kelsie Cowman, Stephanie Allen, Jayabhargav Annam, Ariella Applebaum, Daniel Barboto, Ahmed Khokhar, Brianna J. Lally, Audrey Lee, Max Lee, Avinash Malaviya, Reise Sample, Xiuyi A. Yang, Yang Li, Rafael Ruiz, Raja Thota, Jason Barnhill, Doctor Y. Goldstein, Joan Uehlinger, Scott J. Garforth, Steven C. Almo, Jonathan R. Lai, Morayma Reyes Gil, Amy S. Fox, Kartik Chandran, Tao Wang, Johanna P. Daily, Liise-anne Pirofski

Summary: Convalescent plasma therapy may be beneficial for COVID-19 patients, especially those under 65 years old. Pretransfusion antibody titers are associated with treatment efficacy.

JCI INSIGHT (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Case Report: Prolonged Viral Shedding in Six COVID-19 Patients

Arwa E. Alsaud, Arun Prabhakaran Nair, Ahmad S. Matarneh, Sreethish Sasi, Rania El Hassan, Fahmi Khan, Peter Coyle, Mohamed Abu Khattab, Mouhand F. H. Mohamed

Summary: COVID-19 is a multi-organ disease that primarily affects the respiratory system, and RT-PCR testing is the preferred method for diagnosis. Patients may shed SARS-CoV-2 for several weeks, and the implications of prolonged viral shedding on management and isolation decisions require further research.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2021)

添加到收藏夹

Article Immunology

Duration of Replication-Competent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Shedding Among Patients With Severe or Critical Coronavirus Disease 2019 (COVID-19)

Do Young Kim, Michael Y. Lin, Cheryl Jennings, Haiying Li, Jae Hyung Jung, Nicholas M. Moore, Isaac Ghinai, Stephanie R. Black, Daniel J. Zaccaro, John Brofman, Mary K. Hayden

Summary: The study found that replication-competent SARS-CoV-2 may continue to be shed for up to 45 days after symptom onset in immunocompromised patients with severe or critical COVID-19, compared to only 10 days in immunocompetent patients.

CLINICAL INFECTIOUS DISEASES (2023)

添加到收藏夹

Article Virology

Prolonged corticosteroid therapy and cytomegalovirus infection in patients with severe COVID-19

Yuji Yamamoto, Takayuki Shiroyama, Haruhiko Hirata, Tomoki Kuge, Kinnosuke Matsumoto, Midori Yoneda, Makoto Yamamoto, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Summary: In patients with severe COVID-19 treated with systemic corticosteroid therapy, monitoring cytomegalovirus (CMV) infection is important for preventing secondary infections. The presence of CMV infection is associated with increased risk of mortality during the ICU stay.

JOURNAL OF MEDICAL VIROLOGY (2022)

添加到收藏夹

Article Infectious Diseases

A case of extremely prolonged viral shedding: Could cell cultures be a diagnostic tool to drive COVID-19 patient discharge?

Davide Mileto, Antonella Foschi, Alessandro Mancon, Stefania Merli, Federica Staurenghi, Laura Pezzati, Alberto Rizzo, Federico Conti, Francesca Romeri, Dario Bernacchia, Rachele Meroni, Giuliano Rizzardini, Maria Rita Gismondo, Valeria Micheli

Summary: This study suggests that viral culture may be an important test for patients with COVID-19, especially for those with prolonged viral shedding.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Clinical Neurology

Persistent white matter changes in recovered COVID-19 patients at the 1-year follow-up

Sihong Huang, Zhiguo Zhou, Danhui Yang, Wei Zhao, Mu Zeng, Xingzhi Xie, Yanyao Du, Yingjia Jiang, Xianglin Zhou, Wenhan Yang, Hu Guo, Hui Sun, Ping Liu, Jiyang Liu, Hong Luo, Jun Liu

Summary: The study revealed persistent white matter changes in recovered COVID-19 patients at 1-year follow-up, with slightly more abnormalities seen in patients who were admitted to the ICU. The duration of hospital stay may be a predictor for white matter changes at the 1-year follow-up.

BRAIN (2022)

添加到收藏夹

Article Genetics & Heredity

DRC1 deficiency caused primary ciliary dyskinesia and MMAF in a Chinese patient

Cheng Lei, Danhui Yang, Rongchun Wang, Shuizi Ding, Lin Wang, Ting Guo, Hong Luo

Summary: This study described a novel DRC1 variant in a patient with PCD and MMAF for the first time, and in vitro fertilization was effective for treating infertility in this male patient. The findings expand the genetic spectrum of PCD and MMAF, providing a detailed clinical summary and functional analysis of patients with DRC1 variants.

JOURNAL OF HUMAN GENETICS (2022)

添加到收藏夹

Article Cell Biology

Survivors of COVID-19 exhibit altered amplitudes of low frequency fluctuation in the brain: a resting-state functional magnetic resonance imaging study at 1-year follow-up

Yan-Yao Du, Wei Zhao, Xiang-Lin Zhou, Mu Zeng, Dan-Hui Yang, Xing-Zhi Xie, Si-Hong Huang, Ying-Jia Jiang, Wen-Han Yang, Hu Guo, Hui Sun, Ji-Yang Liu, Ping Liu, Zhi-Guo Zhou, Hong Luo, Jun Liu

Summary: This study found that COVID-19 survivors exhibited altered amplitude of low-frequency fluctuation (ALFF) in brain regions related to mood and sleep regulation during a 1-year follow-up, which provides insights into the neurobiological mechanisms of COVID-19-related neuropsychiatric sequelae.

NEURAL REGENERATION RESEARCH (2022)

添加到收藏夹

Editorial Material Medicine, General & Internal

A novel nonsense mutation of ABCA8 in a patient with reduced HDL-c levels and atherosclerosis

L-L Fan, L. Liu, C-Y Wang, T. Guo, H. Luo

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2022)

添加到收藏夹

Article Medicine, General & Internal

Case Report: Community-Acquired Legionella gormanii Pneumonia in an Immunocompetent Patient Detected by Metagenomic Next-Generation Sequencing

Cheng Lei, Xianglin Zhou, Shuizi Ding, Yingjie Xu, Binyi Yang, Wei Guo, Min Song, Min Yang, Yunan Jia, Hong Luo

Summary: This article reports a case of Legionella gormanii pneumonia diagnosed by metagenomic next-generation sequencing (mNGS). The use of mNGS in diagnosing Legionella infection provides a high-resolution and sensitive assay, especially for non-Legionella pneumophila serogroup 1 strains.

FRONTIERS IN MEDICINE (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Identification of Two Novel DNAAF2 Variants in Two Consanguineous Families with Primary Ciliary Dyskinesia

Chenyang Lu, Danhui Yang, Cheng Lei, Rongchun Wang, Ting Guo, Hong Luo

Summary: Our study revealed novel DNAAF2 variants associated with female infertility and potentially scoliosis in patients with PCD, expanding the understanding of DNAAF2-related disease spectrum.

PHARMACOGENOMICS & PERSONALIZED MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

Characteristics and Follow-Up of Organizing Pneumonia Associated with Haematological Malignancies

Huihui Zeng, Yiming Ma, Xue He, Shan Cai, Ping Chen, Yan Chen, Hong Luo

Summary: This study discusses the characteristics and prognosis of organizing pneumonia (OP) associated with haematological malignancies. The results show that haematological malignancies may be a cause of OP and that minimal invasive biopsy is an effective and safe method for diagnosis. Steroid treatment produces favorable outcomes.

INTERNATIONAL JOURNAL OF GENERAL MEDICINE (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Novel Compound Heterozygous Variants in CCDC40 Associated with Primary Ciliary Dyskinesia and Multiple Morphological Abnormalities of the Sperm Flagella

Yingjie Xu, Binyi Yang, Cheng Lei, Danhui Yang, Shuizi Ding, Chenyang Lu, Lin Wang, Ting Guo, Rongchun Wang, Hong Luo

Summary: This study identified novel compound heterozygous variants in CCDC40 in a male patient with male infertility, confirming the association between CCDC40 and multiple morphological abnormalities of the sperm flagella (MMAF).

PHARMACOGENOMICS & PERSONALIZED MEDICINE (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Identification of a Novel OFD1 Variant in a Patient with Primary Ciliary Dyskinesia

Binyi Yang, Cheng Lei, Danhui Yang, Chenyang Lu, Yingjie Xu, Lin Wang, Ting Guo, Rongchun Wang, Hong Luo

Summary: This study reports a case of a 31-year-old male patient with typical symptoms of primary ciliary dyskinesia (PCD) and identifies a novel variant in OFD1 as the cause. Various examinations reveal abnormalities in the patient's respiratory cilia, while other OFD1-associated symptoms are not present.

PHARMACOGENOMICS & PERSONALIZED MEDICINE (2022)

添加到收藏夹

Article Infectious Diseases

Clinical Characteristics of Chlamydia psittaci Pneumonia Infection in Central South China

Min Yang, Dan-Hui Yang, Huan Yang, Shui-Zi Ding, Cai-Hong Liu, Hui-Ming Yin, Dan Liu, Ping Chen, Hong Luo

Summary: Chlamydia psittaci pneumonia is a complex and variable disease, and the use of mNGS can aid in its diagnosis and treatment. Early treatment with quinolones may benefit patients.

INFECTIOUS DISEASES AND THERAPY (2022)

添加到收藏夹

Article Medicine, General & Internal

Integrative analysis reveals the recurrent genetic etiologies in idiopathic pulmonary fibrosis

S. Guo, Y. Dong, C. Wang, Y. Jiang, R. Xiang, L. -L. Fan, H. Luo, L. Liu

Summary: This study improves the understanding of the molecular basis of IPF through the integration of whole-exome sequencing, bulk RNA sequencing, and single-cell RNA sequencing data. It identifies recurrent genomic and transcriptomic variations in IPF populations, suggesting their significant role in disease development and progression. These findings highlight the importance of an integrative approach in understanding the molecular mechanisms of IPF and identifying potential therapeutic targets.

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2023)

添加到收藏夹

Article Critical Care Medicine

A Double-Blind Randomized Placebo- Controlled Phase 3 Trial of Tobramycin Inhalation Solution in Adults With Bronchiectasis With Pseudomonas Infection

Wei-jie Guan, Jin-fu Xu, Hong Luo, Xing-xiang Xu, Yuan-lin Song, Wan-li Ma, Zong-an Liang, Xue-dong Liu, Guo-jun Zhang, Xiao-ju Zhang, Rong-kai Li, Shu-yang Zhu, Yi-jie Zhang, Xing-jun Cai, Li-ping Wei, Dong-bo Tian, Hui Zhao, Ping-yan Chen, Jie-ming Qu, Nan-shan Zhong, TORNASOL Study Grp

Summary: This study evaluated the efficacy and safety of nebulized tobramycin inhalation solution (TIS) in patients with bronchiectasis with Pseudomonas aeruginosa infection. The results showed that TIS effectively reduced P aeruginosa density and improved the bronchiectasis-specific quality of life.

CHEST (2023)

添加到收藏夹

Review Medicine, General & Internal

Role of extracellular vesicles in lung diseases

Li Zhou, Hong Luo, Jae Woo Lee

Summary: Extracellular vesicles (EVs) are anuclear particles composed of lipid bilayers that transmit biological signals or components to regulate the function of target cells, playing a crucial role in maintaining lung homeostasis and various respiratory diseases. EVs derived from mesenchymal stem cells have shown promising therapeutic effects in reducing and repairing lung injuries. Researchers have also explored methods to enhance EVs-mediated drug delivery for more targeted and beneficial effects.

CHINESE MEDICAL JOURNAL (2022)

添加到收藏夹

Article Critical Care Medicine

High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial

Jingen Xia, Sichao Gu, Wei Lei, Jihua Zhang, Hui Wei, Chao Liu, Han Zhang, Rongli Lu, Liqiong Zhang, Mingyan Jiang, Chao Hu, Zhenshun Cheng, Chaojie Wei, Yusheng Chen, Fengfeng Lu, Min Chen, Hong Bi, Hui Liu, Cunzi Yan, Hong Teng, Yang Yang, Chen Liang, Yanlei Ge, Pengguo Hou, Jialin Liu, Weiwei Gao, Yi Zhang, Yingying Feng, Cheng Tao, Xu Huang, Pinhua Pan, Hong Luo, Chunmei Yun, Qingyuan Zhan

Summary: This multicenter randomized controlled study suggests that HFNC, compared to conventional oxygen therapy, does not reduce the need for intubation in acute COPD exacerbation patients with mild hypercapnia. Future research should focus on patients with respiratory acidosis.

CRITICAL CARE (2022)

添加到收藏夹

Article Genetics & Heredity

Whole-exome sequencing identified a novel homozygous ASPH frameshift variant causing Traboulsi syndrome in a Chinese family

Cheng Lei, Ting Guo, Shuizi Ding, Liyan Liao, Hong Peng, Zhiping Tan, Hong Luo

Summary: This study reported the first Chinese patient with Traboulsi syndrome, identifying the pathogenic gene and clinical characteristics of the disease, while also providing clinical genetic counseling information for other families.

MOLECULAR GENETICS & GENOMIC MEDICINE (2021)

添加到收藏夹

暂无数据

© Peeref 2019-2024. All rights reserved.