Protein Kinase C-δ Mediates Kidney Tubular Injury in Cold Storage–Associated Kidney Transplantation

The Role of Tyrosine Phosphorylation of Protein Kinase C Delta in Infection and Inflammation

(2019) Qingliang Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

OPTN/SRTR 2017 Annual Data Report: Kidney

(2019) A. Hart et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis

(2019) Sung-Gyu Cho et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation

(2019) Olha M. Koval et al.   Science Signaling

Improving the Supply and Quality of Deceased-Donor Organs for Transplantation

(2018) Stefan G. Tullius et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury

(2018) Qingqing Wei et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI

(2017) Heather M. Perry et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal cold storage followed by transplantation impairs expression of key mitochondrial fission and fusion proteins

(2017) Nirmala Parajuli et al.   PLoS One

Improved renal ischemia tolerance in females influences kidney transplantation outcomes

(2016) David D. Aufhauser et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamin-Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy

(2016) B. A. Ayanga et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cellular and Molecular Mechanisms of AKI

(2016) A. Agarwal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Protein Kinase C δ Suppresses Autophagy to Induce Kidney Cell Apoptosis in Cisplatin Nephrotoxicity

(2016) Dongshan Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Nonapoptotic cell death in acute kidney injury and transplantation

(2016) Andreas Linkermann   KIDNEY INTERNATIONAL

Mitochondrial dysfunction in inherited renal disease and acute kidney injury

(2016) Francesco Emma et al.   Nature Reviews Nephrology

Multifunctional roles of PKCδ: Opportunities for targeted therapy in human disease

(2016) Mary E. Reyland et al.   PHARMACOLOGY & THERAPEUTICS

Mitochondria in Acute Kidney Injury

(2016) Kenneth M. Ralto et al.   SEMINARS IN NEPHROLOGY

Targeting Endogenous Repair Pathways after AKI

(2015) B. D. Humphreys et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hyperglycemia, p53, and mitochondrial pathway of apoptosis are involved in the susceptibility of diabetic models to ischemic acute kidney injury

(2015) Jianping Peng et al.   KIDNEY INTERNATIONAL

Each additional hour of cold ischemia time significantly increases the risk of graft failure and mortality following renal transplantation

(2015) Agnes Debout et al.   KIDNEY INTERNATIONAL

An Unanticipated Role for Survivin in Organ Transplant Damage

(2014) P. Cassis et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The many hats of protein kinase Cδ: one enzyme with many functions

(2014) Nir Qvit et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI Randomized Controlled Trial

(2014) A. Michael Lincoff et al.   EUROPEAN HEART JOURNAL

Regulated Cell Death in AKI

(2014) A. Linkermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Delayed kidney graft function: from mechanism to translation

(2014) Bernd Schröppel et al.   KIDNEY INTERNATIONAL

Immune cells in experimental acute kidney injury

(2014) Hye Ryoun Jang et al.   Nature Reviews Nephrology

Cell cycle control in the kidney

(2014) Dana Thomasova et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology

(2013) Ming Zhan et al.   KIDNEY INTERNATIONAL

Mitochondrial Fission Triggered by Hyperglycemia Is Mediated by ROCK1 Activation in Podocytes and Endothelial Cells

(2012) Wenjian Wang et al.   Cell Metabolism

Cellular Senescence Limits Regenerative Capacity and Allograft Survival

(2012) H. Braun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

AKI in kidney transplant recipients—here to stay

(2012) Edward J. Nehus et al.   Nature Reviews Nephrology

Influence of CIT-Induced DGF on Kidney Transplant Outcomes

(2011) L. K. Kayler et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Distribution of KAI-9803, a Novel  -Protein Kinase C Inhibitor, after Intravenous Administration to Rats

(2011) Y. Miyaji et al.   DRUG METABOLISM AND DISPOSITION

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

(2011) Navjotsingh Pabla et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular pathophysiology of ischemic acute kidney injury

(2011) Joseph V. Bonventre et al.   JOURNAL OF CLINICAL INVESTIGATION

Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis

(2010) Craig Brooks et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Quantitative assessment of markers for cell senescence

(2010) Conor Lawless et al.   EXPERIMENTAL GERONTOLOGY

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

PKC-  Promotes Renal Tubular Cell Apoptosis Associated with Proteinuria

(2010) X. Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo

(2010) Xin Qi et al.   MOLECULAR BIOLOGY OF THE CELL

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models

(2009) Craig Brooks et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural Basis of Protein Kinase C Isoform Function

(2008) Susan F. Steinberg   PHYSIOLOGICAL REVIEWS