Article
Chemistry, Multidisciplinary
Pau Font, Hugo Valdes, Gregorio Guisado-Barrios, Xavi Ribas
Summary: Oxidant-free Au-catalyzed reactions are gaining attention as a new tool for innovative organic transformations. This study successfully demonstrated the synthesis of two Au(i) complexes and proposed a rational design for oxidant-free Au-catalyzed reactions. A novel Au(i)-catalytic procedure for the synthesis of gamma-substituted gamma-butyrolactones was developed based on the fundamental knowledge gained on the redox properties of Au(i)/Au(iii) systems.
Article
Chemistry, Multidisciplinary
Yan Wu, Jin-Yang Chen, Jing Ning, Xue Jiang, Jie Deng, Yu Deng, Rui Xu, Wei-Min He
Summary: An electrochemical multicomponent reaction was developed for the construction of 4-selanylpyrazoles under catalyst- and chemical-oxidant-free conditions, providing a green and straightforward protocol. A variety of 4-selanylpyrazole derivatives were synthesized from readily available raw materials with good to excellent yields.
Article
Chemistry, Multidisciplinary
Yongqiang Zhang, Yunhe Jin, Lifang Wang, Qingqing Zhang, Changgong Meng, Chunying Duan
Summary: The visible light-induced metal-free C(sp(3))-H phenanthridinylation of simple alkanes with isonitrile using H2O2 as a terminal green oxidant enables practical access to valuable alkyl-substituted phenanthridine derivatives with good yields and selectivities under mild conditions and broad substrate scope, including gaseous alkanes.
Review
Chemistry, Multidisciplinary
David M. Kitcatt, Simon Nicolle, Ai-Lan Lee
Summary: This review summarizes the recent progress on using carboxylic acids directly as convenient radical precursors for the formation of carbon-carbon bonds.
CHEMICAL SOCIETY REVIEWS
(2022)
Article
Chemistry, Applied
Jianyu Dong, Xiuling Chen, Fangyan Ji, Lixin Liu, Lebin Su, Min Mo, Jian-Sheng Tang, Yongbo Zhou
Summary: In the presence of copper salt and molecular oxygen, a simple and direct aerobic oxidative esterification reaction of arylacetonitriles with alcohols/phenols is achieved, resulting in a broad range of aryl carboxylic acid esters in good to high yields. Copper salt plays multiple roles in the transformation, facilitating the oxygenation of C-H bond, cleavage of inert C-C bond, and formation of C-O bond in one pot without the need for any additional acids, bases, ligands, etc. This reaction provides a simple, direct, and efficient method for synthesizing functionalized esters, especially aryl benzoates, from readily available starting materials.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Xiao-Xiao Yan, Wen-Xiu Lu, Jian-Gang Mao, Jian Xing, Hong-Yu Tang, Shu-Yi Huang, Wen Jiang
Summary: A concise and efficient synthesis method of direct esterificationof aldehydes via Pd-catalyzed C-H bond activation of aldehydegroup has been developed. The strategy avoids the preoxidation stepof aldehyde or use of condensing agents in ester synthesis, and is applicable to various alcohols and difficult-to-esterify phenolics. The methodology has the significant advantages of broad substrate scope, mild reaction conditions, and nonrequirement of additional oxidants.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Jing Shi, Xue-Wang Gao, Qing-Xiao Tong, Jian-Ji Zhong
Summary: This novel strategy combines light-promotion and tertiary-amine assistance to efficiently access beta-hydroxysulfides. In contrast to traditional methods, this approach offers mild reaction conditions, high efficiency, and excellent functional group tolerance.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Plant Sciences
Fuyou Xiang, Wen-Cheng Liu, Xin Liu, Yuwei Song, Yu Zhang, Xiaojing Zhu, Pengtao Wang, Siyi Guo, Chun-Peng Song
Summary: During seed germination, plants utilize the CYP77A4 gene to catalyze the epoxidation of unsaturated fatty acids, balancing energy supply and reactive oxygen species (ROS) production to prevent oxidative damage.
Review
Food Science & Technology
Matthias D. Eisner
Summary: Indirect and direct heating are common technologies used in the dairy industry, especially for UHT milk, with direct heating chosen for maintaining sensitive ingredients and ensuring sufficient microbial inactivation. Technical principles reveal differences in product/steam mixing, hydrodynamic forces, gas/volatile removal, product dilution, and fouling, impacting processing unit design and milk constituents.
INTERNATIONAL DAIRY JOURNAL
(2021)
Article
Chemistry, Inorganic & Nuclear
Jan Zechovsky, Vit Kremlacek, Milan Erben, Martin Hejda, Elena Rychagova, Roman Jambor, Ales Ruzicka, Sergey Ketkov, Libor Dostal
Summary: This paper reports the reactivity of two types of organopnictogen(I) N,C,N-pincer ligand coordinated compound towards an electron-deficient alkyne, dimethyl acetylenedicarboxylate (DMAD). The reactions show significant examples of element-ligand cooperation. The compounds react via dearomatization of a latent heteropnictole ring, producing rare examples of hetero Diels-Alder (DA) adducts. Furthermore, the study includes a theoretical survey to describe the main thermodynamic parameters and reaction pathways.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Organic
Ravi Kant Yadav, Richa Sharma, Deepak Gautam, Jyoti Joshi, Sandeep Chaudhary
Summary: In this study, a new and fast halogenating reagent system was developed using Lewis acid AlX3 and tert-butyl hydroperoxide (TBHP) for direct regioselective halogenation, leading to the synthesis of various fused bi-/tri-cyclic hetero-aromatic compounds. The protocol is operationally simple and provides high yields, showcasing the versatility and compatibility of the new catalyst.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Organic
Yan-Jun Zhuang, Jian-Ping Qu, Yan-Biao Kang
JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Organic
Hua Wang, Jie Liu, Jian-Ping Qu, Yan-Biao Kang
JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Organic
Xiang-Huan Shan, Mei-Mei Wang, Lin Tie, Jian-Ping Qu, Yan-Biao Kang
Article
Chemistry, Organic
Qing Huang, Ya-Wei Li, Xiao-Shan Ning, Guo-Qing Jiang, Xiao-Wei Zhang, Jian-Ping Qu, Yan-Biao Kang
Article
Chemistry, Organic
Ting-Hui Ding, Jian-Ping Qu, Yan-Biao Kang
Article
Chemistry, Organic
Ya-Wei Li, Hong-Xing Zheng, Bo Yang, Xiang-Huan Shan, Jian-Ping Qu, Yan-Biao Kang
Article
Chemistry, Multidisciplinary
Zi-Hong Luan, Jian-Ping Qu, Yan-Biao Kang
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2020)
Article
Chemistry, Organic
Xiao-Wei Zhang, Guo-Qing Jiang, Shu-Hui Lei, Xiang-Huan Shan, Jian-Ping Qu, Yan-Biao Kang
Summary: An iron-catalyzed alpha,beta-dehydrogenation reaction was developed for a broad spectrum of carbonyl compounds or analogues, providing a simple one-step conversion to their alpha,beta-unsaturated counterparts with high yields.
Article
Chemistry, Organic
Hua Wang, Jian-Ping Qu, Yan-Biao Kang
Summary: The recyclable organic photoreductant CBZ6 catalyzes the reductive coupling of aldehydes, ketones, and imines under purple light irradiation, producing 1,2-diols and 1,2-diamines. With a high oxidation potential, CBZ6 is suitable for the reductive coupling of carbonyl compounds and their derivatives, making it a promising candidate for large-scale photoreductive synthesis.
Article
Chemistry, Organic
Shu-Hui Lei, Ya Zhong, Xian-Peng Cai, Qing Huang, Jian-Ping Qu, Yan-Biao Kang
Summary: A tandem isomerization-anti-Markovnikov oxidation method has been developed using bis(benzonitrile)palladium chloride catalyst and O-2 as the sole oxidant, regiospecifically yielding beta-amino aldehydes. tert-Butyl nitrite serves as a simple and only redox cocatalyst, with (BuOH)-Bu-t as a crucial solvent for achieving excellent yield and specificity toward anti-Markovnikov aldehyde products.
Article
Chemistry, Organic
Peng-Fei Dai, Yi-Ping Wang, Jian-Ping Qu, Yan-Biao Kang
Summary: A synthetically practical transition metal/catalyst/halogen-free dehydrogenative coupling of aldehydes with N-hydroxyimides solely promoted by tert-butyl nitrite under mild conditions was developed. A diverse array of N-hydroxyimide esters can be prepared from either aliphatic or aromatic aldehydes, with benzoyl-substituted aldehydes also being suitable.
Article
Chemistry, Organic
Shu-Hui Lei, Ya Zhong, Xian-Peng Cai, Qing Huang, Jian-Ping Qu, Yan-Biao Kang
Summary: A simple and practical method for the preparation of beta-O substituted aldehydes directly from linear allylic esters has been developed. By using a specific catalyst and oxidant, the reaction proceeds smoothly to give the desired products, showing broad substrate scope and excellent regioselectivity.
ORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Organic
Lin Tie, Xiang-Huan Shan, Jian-Ping Qu, Yan-Biao Kang
Summary: An efficient and practical transition metal-free alpha-trideuteration of methylarenes has been developed using inexpensive bases in DMSO-d(6) solvent. This method is applicable to a wide range of methylarenes and allows for the introduction of a trideuteriomethyl group to aromatics with excellent selectivity.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Review
Chemistry, Organic
Peng-Fei Dai, Hua Wang, Xian-Chao Cui, Jian-Ping Qu, Yan-Biao Kang
ORGANIC CHEMISTRY FRONTIERS
(2020)
Article
Chemistry, Multidisciplinary
Xiang-Huan Shan, Bo Yang, Jian-Ping Qu, Yan-Biao Kang
CHEMICAL COMMUNICATIONS
(2020)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
