A methylation-switchable conformational probe for the sensitive and selective detection of RNA demethylase activity

The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

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Structure and Thermodynamics of N6-Methyladenosine in RNA: A Spring-Loaded Base Modification

(2015) Caroline Roost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO

(2015) Joel D. W. Toh et al.   Chemical Science

Fate by RNA methylation: m6A steers stem cell pluripotency

(2015) Boxuan Zhao et al.   GENOME BIOLOGY

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

The dynamic epitranscriptome: N6-methyladenosine and gene expression control

(2014) Kate D. Meyer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate

(2012) Marcella Ma et al.   BIOCHEMICAL JOURNAL

Dynamic Combinatorial Mass Spectrometry Leads to Inhibitors of a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

(2012) Esther C. Y. Woon et al.   JOURNAL OF MEDICINAL CHEMISTRY

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

(2012) Nathan R. Rose et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of Cell-Active N6-Methyladenosine RNA Demethylase FTO Inhibitor

(2012) Baoen Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unraveling a Connection between DNA Demethylation Repair and Cancer

(2011) Manel Camps et al.   MOLECULAR CELL

Transient Hoogsteen base pairs in canonical duplex DNA

(2011) Evgenia N. Nikolova et al.   NATURE

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Direct Detection and Quantification of Methylation in Nucleic Acid Sequences Using High-Resolution Melting Analysis

(2010) Carlos M. Rodríguez López et al.   ANALYTICAL CHEMISTRY

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

Active DNA demethylation: many roads lead to Rome

(2010) Susan C. Wu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure determination of DNA methylation lesions N 1 -meA and N 3 -meC in duplex DNA using a cross-linked protein–DNA system

(2010) Lianghua Lu et al.   NUCLEIC ACIDS RESEARCH

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

Effect of 1-methyladenine on double-helical DNA structures

(2008) Hao Yang et al.   FEBS LETTERS