4.7 Article

A DNAzyme-mediated logic gate for programming molecular capture and release on DNA origami

期刊

CHEMICAL COMMUNICATIONS
卷 52, 期 54, 页码 8369-8372

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc02989b

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  1. U.S. Office of Naval Research
  2. Naval Research Laboratory Nanosciences Institute
  3. Defense Threat Reduction Agency
  4. Directorate For Engineering
  5. Div Of Civil, Mechanical, & Manufact Inn [1055866] Funding Source: National Science Foundation
  6. Div Of Chem, Bioeng, Env, & Transp Sys
  7. Directorate For Engineering [1512537] Funding Source: National Science Foundation

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Here we design a DNA origami-based site-specific molecular capture and release platform operated by a DNAzyme-mediated logic gate process. We show the programmability and versatility of this platform with small molecules, proteins, and nanoparticles, which may also be controlled by external light signals.

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