Tuning Macrophage Phenotype to Mitigate Skeletal Muscle Fibrosis

Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing

(2020) Michael Sorkin et al.   Nature Communications

High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations

(2019) Lorenzo Giordani et al.   MOLECULAR CELL

Regulation and Functions of 15-Lipoxygenases in Human Macrophages

(2019) Ryan G. Snodgrass et al.   Frontiers in Pharmacology

Tackling muscle fibrosis: From molecular mechanisms to next generation engineered models to predict drug delivery

(2018) S. Bersini et al.   ADVANCED DRUG DELIVERY REVIEWS

Immunology Guides Skeletal Muscle Regeneration

(2018) F. Sass et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MyoVision: software for automated high-content analysis of skeletal muscle immunohistochemistry

(2018) Yuan Wen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Genetic manipulation of CCN2/CTGF unveils cell-specific ECM-remodeling effects in injured skeletal muscle

(2018) Jennifer M. Petrosino et al.   FASEB JOURNAL

Anti-CTGF Oligonucleotide Reduces Severity of Postsurgical Hypertrophic Scars in a Randomized, Double-Blind, Within-Subject, Placebo-Controlled Study

(2018) Jeff Jensen et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy

(2018) Barbora Malecova et al.   Nature Communications

Skeletal muscle fibrosis: an overview

(2018) Mohamed A. A. Mahdy   CELL AND TISSUE RESEARCH

Traumatic muscle fibrosis

(2017) David Cholok et al.   Journal of Trauma and Acute Care Surgery

Traumatic muscle fibrosis

(2017) David Cholok et al.   Journal of Trauma and Acute Care Surgery

ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

(2017) David Gonzalez et al.   PLoS One

Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis

(2016) Osvaldo Contreras et al.   CELL AND TISSUE RESEARCH

Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding

(2016) Senem Aykul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transforming growth factor beta (TGF-β) isoforms in wound healing and fibrosis

(2016) Michael K. Lichtman et al.   WOUND REPAIR AND REGENERATION

Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma

(2016) Carlos A. Aguilar et al.   Stem Cell Reports

Comparative Study of Injury Models for Studying Muscle Regeneration in Mice

(2016) David Hardy et al.   PLoS One

Macrophages Promote Osteoblastic Differentiation In Vivo: Implications in Fracture Repair and Bone Homeostasis

(2015) Linda Vi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Fibrogenic Cell Plasticity Blunts Tissue Regeneration and Aggravates Muscular Dystrophy

(2015) Patrizia Pessina et al.   Stem Cell Reports

Myofiber-specific inhibition of TGFβ signaling protects skeletal muscle from injury and dystrophic disease in mice

(2014) Federica Accornero et al.   HUMAN MOLECULAR GENETICS

Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice

(2014) Clare L. Abram et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Monocyte/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration

(2013) Marielle Saclier et al.   FEBS Journal

Macrophage activation and skeletal muscle healing following traumatic injury

(2013) Margaret L Novak et al.   JOURNAL OF PATHOLOGY

Collagen VI regulates satellite cell self-renewal and muscle regeneration

(2013) Anna Urciuolo et al.   Nature Communications

LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types

(2012) Jung H Kim et al.   BMC GENOMICS

Interleukin-6/Signal Transducer and Activator of Transcription 3 (STAT3) Pathway Is Essential for Macrophage Infiltration and Myoblast Proliferation during Muscle Regeneration

(2012) Congcong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

(2011) M. M. Murphy et al.   DEVELOPMENT

Rapid quantification of myocardial fibrosis: a new macro-based automated analysis

(2011) Awal M. Hadi et al.   CELLULAR ONCOLOGY

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury

(2009) Madly Brigitte et al.   ARTHRITIS AND RHEUMATISM

A CREB-C/EBP  cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

(2009) D. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual and Beneficial Roles of Macrophages During Skeletal Muscle Regeneration

(2008) Bénédicte Chazaud et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Suppression of macrophage functions impairs skeletal muscle regeneration with severe fibrosis

(2008) M SEGAWA et al.   EXPERIMENTAL CELL RESEARCH

Antisense inhibition of connective tissue growth factor (CTGF/CCN2) mRNA limits hypertrophic scarring without affecting wound healing in vivo

(2008) Mark Sisco et al.   WOUND REPAIR AND REGENERATION