Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction

Systemic Inflammation and Myelofibrosis in a Patient with Takenouchi-Kosaki Syndrome due to CDC42 Tyr64Cys Mutation

(2020) Giorgia Bucciol et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Haematopoietic stem cell activity and interactions with the niche

(2019) Sandra Pinho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation

(2019) Nour J. Abdulhay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pairing JAK with MEK for improved therapeutic efficiency in myeloproliferative disorders

(2019) David A. Williams   JOURNAL OF CLINICAL INVESTIGATION

Drosophila as a Genetic Model for Hematopoiesis

(2019) Utpal Banerjee et al.   GENETICS

The bone marrow microenvironment at single-cell resolution

(2019) Anastasia N. Tikhonova et al.   NATURE

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

(2019) Michael T. Lam et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes

(2018) Simone Martinelli et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Genetic Landscape of Diamond-Blackfan Anemia

(2018) Jacob C. Ulirsch et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Classification and Personalized Prognosis in Myeloproliferative Neoplasms

(2018) Jacob Grinfeld et al.   NEW ENGLAND JOURNAL OF MEDICINE

Leptin-receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis

(2017) Matthew Decker et al.   NATURE CELL BIOLOGY

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Chromothriptic Cure of WHIM Syndrome

(2015) David H. McDermott et al.   CELL

Wash functions downstream of Rho1 GTPase in a subset of Drosophila immune cell developmental migrations

(2015) Jeffrey M. Verboon et al.   MOLECULAR BIOLOGY OF THE CELL

Timing, rates and spectra of human germline mutation

(2015) Raheleh Rahbari et al.   NATURE GENETICS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

miRNA-mRNA integrative analysis in primary myelofibrosis CD34+ cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

(2014) R. Norfo et al.   BLOOD

Coordination of Rho Family GTPase Activities to Orchestrate Cytoskeleton Responses during Cell Wound Repair

(2014) Maria Teresa Abreu-Blanco et al.   CURRENT BIOLOGY

Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms

(2014) Lorena Arranz et al.   NATURE

Altered translation of GATA1 in Diamond-Blackfan anemia

(2014) Leif S Ludwig et al.   NATURE MEDICINE

Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche

(2013) Koen Schepers et al.   Cell Stem Cell

GEMINI: Integrative Exploration of Genetic Variation and Genome Annotations

(2013) Umadevi Paila et al.   PLoS Computational Biology

Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections

(2012) Amandine Crequer et al.   JOURNAL OF CLINICAL INVESTIGATION

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data

(2011) H. Li   BIOINFORMATICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila

(2010) Daria Siekhaus et al.   NATURE CELL BIOLOGY

Rho GTPases in hematopoiesis and hemopathies

(2009) J. C. Mulloy et al.   BLOOD

Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence

(2008) J.-J. Lataillade et al.   BLOOD