Design, synthesis, and structure-activity relationship studies of novel pleuromutilin derivatives having a piperazine ring

Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold

(2015) Edward Avilés et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Copper-Catalyzed Double Additions and Radical Cyclization Cascades in the Re-Engineering of the Antibacterial Pleuromutilin

(2015) Rebecca E. Ruscoe et al.   CHEMISTRY-A EUROPEAN JOURNAL

Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ

(2015) Xin Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A click chemistry approach to pleuromutilin derivatives. Part 3: Extended footprinting analysis and excellent MRSA inhibition for a derivative with an adenine phenyl side chain

(2014) Ida Dreier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Biological Activities of Novel Pleuromutilin Derivatives with a Substituted Thiadiazole Moiety as Potent Drug-Resistant Bacteria Inhibitors

(2014) Ruofeng Shang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Structure–Activity Relationship Studies of Novel Thioether Pleuromutilin Derivatives as Potent Antibacterial Agents

(2014) Chenyu Ling et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and synthetic chemistry of pleuromutilin

(2014) Neal J. Fazakerley et al.   TETRAHEDRON

Total Synthesis of (+)-Pleuromutilin

(2013) Neal J. Fazakerley et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mannich bases of 7-piperazinylquinolones and kojic acid derivatives: Synthesis, in vitro antibacterial activity and in silico study

(2013) Saeed Emami et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities

(2013) Meltem Yolal Mentese et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

SYNTHESIS AND IN VITRO ANTIBACTERIAL ACTIVITY OF FOUR NOVEL PLEUROMUTILIN DERIVATIVES

(2013) YOUZHI TANG et al.   JOURNAL OF THE CHILEAN CHEMICAL SOCIETY

A Click Chemistry Approach to Pleuromutilin Derivatives, Part 2: Conjugates with Acyclic Nucleosides and Their Ribosomal Binding and Antibacterial Activity

(2012) Ida Dreier et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of the Pleuromutilin Antibiotic SB-268091: A New Practical and Efficient Synthesis of Quinuclidine-4-thiol

(2012) Bernie Choudary et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Avogadro: an advanced semantic chemical editor, visualization, and analysis platform

(2012) Marcus D Hanwell et al.   Journal of Cheminformatics

The synthesis of C-13 functionalized pleuromutilins via C–H amidation and subsequent novel rearrangement product

(2011) Daniel P. Uccello et al.   TETRAHEDRON LETTERS

Pleuromutilin derivatives having a purine ring. Part 3: Synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer

(2008) Yoshimi Hirokawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Click Chemistry Approach to Pleuromutilin Conjugates with Nucleosides or Acyclic Nucleoside Derivatives and Their Binding to the Bacterial Ribosome

(2008) Line Lolk et al.   JOURNAL OF MEDICINAL CHEMISTRY

The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome

(2003) Susan M. Poulsen et al.   MOLECULAR MICROBIOLOGY