NLRC3 inhibits PDGF‐induced PASMCs proliferation via PI3K‐mTOR pathway

NLRC3 inhibits MCT-induced pulmonary hypertension in rats via attenuating PI3K activation

(2019) Li-Huang Zha et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension

(2019) Marius M. Zucker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

PFKFB3 in Smooth Muscle Promotes Vascular Remodeling in Pulmonary Arterial Hypertension

(2019) Laszlo Kovacs et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibition of CHK1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension

(2019) Alice Bourgeois et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension

(2019) Astrid Weiss et al.   Nature Communications

Endothelial and Smooth Muscle Cell Interaction via FoxM1 Signaling Mediates Vascular Remodeling and Pulmonary Hypertension

(2018) Zhiyu Dai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sirtuin 1 regulates pulmonary artery smooth muscle cell proliferation

(2018) Giada Zurlo et al.   JOURNAL OF HYPERTENSION

Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting vascular remodeling in rats

(2018) Ruizan Shi et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Pulmonary arterial hypertension: pathogenesis and clinical management

(2018) Thenappan Thenappan et al.   BMJ-British Medical Journal

Pulmonary arterial hypertension: pathogenesis and clinical management

(2018) Thenappan Thenappan et al.   BMJ-British Medical Journal

Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway

(2018) Jingbo Dai et al.   Nature Communications

NLRC3: A Novel Noninvasive Biomarker for Pulmonary Hypertension Diagnosis

(2018) Li-huang Zha et al.   Aging and Disease

Identification of Novel Therapeutic Targets for Pulmonary Arterial Hypertension

(2018) Kimio Satoh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pathology and Pathobiology of Pulmonary Hypertension

(2017) Peter Dorfmüller et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Targeting Vascular Remodeling to Treat Pulmonary Arterial Hypertension

(2017) A.A. Roger Thompson et al.   TRENDS IN MOLECULAR MEDICINE

Let-7a-transfected mesenchymal stem cells ameliorate monocrotaline-induced pulmonary hypertension by suppressing pulmonary artery smooth muscle cell growth through STAT3-BMPR2 signaling

(2017) Gesheng Cheng et al.   Stem Cell Research & Therapy

Endothelial and Smooth Muscle Cell Interactions in the Pathobiology of Pulmonary Hypertension

(2016) Yuansheng Gao et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pulmonary vascular remodeling in pulmonary hypertension

(2016) Rubin M. Tuder   CELL AND TISSUE RESEARCH

NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer

(2016) Rajendra Karki et al.   NATURE

Activation of AMPK inhibits PDGF-induced pulmonary arterial smooth muscle cells proliferation and its potential mechanisms

(2016) Yang Song et al.   PHARMACOLOGICAL RESEARCH

Effect of imatinib as add-on therapy on echocardiographic measures of right ventricular function in patients with significant pulmonary arterial hypertension

(2014) A. M. Shah et al.   EUROPEAN HEART JOURNAL

PI3K and cancer: lessons, challenges and opportunities

(2014) David A. Fruman et al.   NATURE REVIEWS DRUG DISCOVERY

Rapamycin Reverses Pulmonary Artery Smooth Muscle Cell Proliferation in Pulmonary Hypertension

(2013) Amal Houssaini et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Targeting cell motility in pulmonary arterial hypertension

(2013) R. Paulin et al.   EUROPEAN RESPIRATORY JOURNAL

Targeting the serotonin pathway for the treatment of pulmonary arterial hypertension

(2013) Matthew Thomas et al.   PHARMACOLOGY & THERAPEUTICS

BDNF/TrkB Signaling Augments Smooth Muscle Cell Proliferation in Pulmonary Hypertension

(2012) Grazyna Kwapiszewska et al.   AMERICAN JOURNAL OF PATHOLOGY

Oestradiol ameliorates monocrotaline pulmonary hypertensionviaNO, prostacyclin and endothelin-1 pathways

(2012) Ping Yuan et al.   EUROPEAN RESPIRATORY JOURNAL

Hypoxia Enhances Platelet-derived Growth Factor Signaling in the Pulmonary Vasculature by Down-Regulation of Protein Tyrosine Phosphatases

(2010) Henrik ten Freyhaus et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY