Coinhibition of S1PR1 and GP130 by siRNA‐loaded alginate‐conjugated trimethyl chitosan nanoparticles robustly blocks development of cancer cells

Silencing of p68 and STAT3 synergistically diminishes cancer progression

(2020) Vida Hashemi et al.   LIFE SCIENCES

Silencing of IL-6 and STAT3 by siRNA loaded hyaluronate-N,N,N-trimethyl chitosan nanoparticles potently reduces cancer cell progression

(2020) Ali Masjedi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Codelivery of STAT3 siRNA and BV6 by carboxymethyl dextran trimethyl chitosan nanoparticles suppresses cancer cell progression

(2020) Afshin Nikkhoo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nanomedicine for improvement of dendritic cell-based cancer immunotherapy

(2020) Vida Hashemi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

S1PR1 regulates the switch of two angiogenic modes by VE-cadherin phosphorylation in breast cancer

(2019) Shuang Liu et al.   Cell Death & Disease

S1PR1 as a Novel Promising Therapeutic Target in Cancer Therapy

(2019) Narges Rostami et al.   Molecular Diagnosis & Therapy

Downregulation of A2AR by siRNA loaded PEG-chitosan-lactate nanoparticles restores the T cell mediated anti-tumor responses through blockage of PKA/CREB signaling pathway

(2019) Ali Masjedi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

S1PR1 promotes proliferation and inhibits apoptosis of esophageal squamous cell carcinoma through activating STAT3 pathway

(2019) Yan Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The mechanism of the premetastatic niche facilitating colorectal cancer liver metastasis generated from myeloid-derived suppressor cells induced by the S1PR1–STAT3 signaling pathway

(2019) Qi Lin et al.   Cell Death & Disease

Blockage of immune checkpoint molecules increases T‐cell priming potential of dendritic cell vaccine

(2019) Hadi Hassannia et al.   IMMUNOLOGY

Down-regulating IL-6/GP130 targets improved the anti-tumor effects of 5-fluorouracil in colon cancer

(2018) Sanhong Li et al.   APOPTOSIS

Sphingosine-1-phosphate promotes the proliferation and attenuates apoptosis of Endothelial progenitor cells via S1PR1/S1PR3/PI3K/Akt pathway

(2018) Hang Wang et al.   CELL BIOLOGY INTERNATIONAL

Anti-angiogenic effects of CD73-specific siRNA-loaded nanoparticles in breast cancer-bearing mice

(2018) Ghasem Ghalamfarsa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

N -trimethyl chitosan nanoparticles and CSKSSDYQC peptide: N -trimethyl chitosan conjugates enhance the oral bioavailability of gemcitabine to treat breast cancer

(2018) Guanyu Chen et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticles and targeted drug delivery in cancer therapy

(2017) Behdokht Bahrami et al.   IMMUNOLOGY LETTERS

CD73 specific siRNA loaded chitosan lactate nanoparticles potentiate the antitumor effect of a dendritic cell vaccine in 4T1 breast cancer bearing mice

(2017) Farhad Jadidi-Niaragh et al.   JOURNAL OF CONTROLLED RELEASE

Increased efficacy of a dendritic cell–based therapeutic cancer vaccine with adenosine receptor antagonist and CD73 inhibitor

(2017) Samaneh Arab et al.   TUMOR BIOLOGY

Inhibition of HIF-1α enhances anti-tumor effects of dendritic cell-based vaccination in a mouse model of breast cancer

(2016) Nasim Kheshtchin et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IL-6 mediates the signal pathway of JAK-STAT3-VEGF-C promoting growth, invasion and lymphangiogenesis in gastric cancer

(2016) GUIBIN ZHAO et al.   ONCOLOGY REPORTS

Downregulation of CD73 in 4T1 breast cancer cells through siRNA-loaded chitosan-lactate nanoparticles

(2016) Farhad Jadidi-Niaragh et al.   TUMOR BIOLOGY

Glycoprotein 130 is associated with adverse postoperative clinical outcomes of patients with late-stage non-metastatic gastric cancer

(2016) Yifan Cao et al.   Scientific Reports

Bactericidal activity of hydrogel beads based on N,N,N-trimethyl chitosan/alginate complexes loaded with silver nanoparticles

(2015) Alessandro F. Martins et al.   CHINESE CHEMICAL LETTERS

Preparation and cytotoxicity of N,N,N-trimethyl chitosan/alginate beads containing gold nanoparticles

(2015) Alessandro F. Martins et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Versatile functions for IL-6 in metabolism and cancer

(2015) Jan Mauer et al.   TRENDS IN IMMUNOLOGY

Myeloid-derived suppressor cells in B cell malignancies

(2015) Yaghoub Yazdani et al.   TUMOR BIOLOGY

Preparation methods of alginate nanoparticles

(2014) Jerome P. Paques et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

The chick embryo chorioallantoic membrane as a model for tumor biology

(2014) Domenico Ribatti   EXPERIMENTAL CELL RESEARCH

Aberrant expression of sphingosine-1-phosphate receptor 1 correlates with metachronous liver metastasis and poor prognosis in colorectal cancer

(2014) Qi Lin et al.   TUMOR BIOLOGY

Increased Frequency of CD8+and CD4+Regulatory T Cells in Chronic Lymphocytic Leukemia: Association with Disease Progression

(2013) Farhad Jadidi-Niaragh et al.   CANCER INVESTIGATION

gp130: a promising drug target for cancer therapy

(2013) Shili Xu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Characterization of N-trimethyl chitosan/alginate complexes and curcumin release

(2013) Alessandro F. Martins et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Regulatory T cells in chronic lymphocytic leukemia: implication for immunotherapeutic interventions

(2013) Farhad Jadidi-Niaragh et al.   TUMOR BIOLOGY

S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites

(2012) Jiehui Deng et al.   CANCER CELL

Chitosan-Alginate Blended Nanoparticles as Carriers for the Transmucosal Delivery of Macromolecules

(2009) Francisco M. Goycoolea et al.   BIOMACROMOLECULES

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Evaluation of chitosan salts as non-viral gene vectors in CHO-K1 cells

(2007) W WEECHARANGSAN et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS