Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint

Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation

(2020) Sofia Cunha-Silva et al.   JOURNAL OF CELL BIOLOGY

Cyclin B1 scaffolds MAD 1 at the kinetochore corona to activate the mitotic checkpoint

(2020) Lindsey A Allan et al.   EMBO JOURNAL

CDK1-CCNB1 creates a spindle checkpoint–permissive state by enabling MPS1 kinetochore localization

(2019) Daniel Hayward et al.   JOURNAL OF CELL BIOLOGY

MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling

(2019) Tatiana Alfonso-Pérez et al.   JOURNAL OF CELL BIOLOGY

Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein’s C-Terminal Helix

(2019) Benjamin R. Topacio et al.   MOLECULAR CELL

The Importance of Kinase–Phosphatase Integration: Lessons from Mitosis

(2018) Lendert Gelens et al.   TRENDS IN CELL BIOLOGY

Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis

(2017) Bernhard Strauss et al.   JOURNAL OF CELL BIOLOGY

An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint

(2017) Junbin Qian et al.   MOLECULAR CELL

Cellular Reorganization during Mitotic Entry

(2017) Lysie Champion et al.   TRENDS IN CELL BIOLOGY

Molecular mechanism of APC/C activation by mitotic phosphorylation

(2016) Suyang Zhang et al.   NATURE

Mechanism of APC/CCDC20activation by mitotic phosphorylation

(2016) Renping Qiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclin-dependent kinase 1-dependent activation of APC/C ubiquitin ligase

(2016) K. Fujimitsu et al.   SCIENCE

Interphase APC/C–Cdc20 inhibition by cyclin A2–Cdk2 ensures efficient mitotic entry

(2016) Jamin B. Hein et al.   Nature Communications

CRISPR-Cas9D10A nickase-based genotypic and phenotypic screening to enhance genome editing

(2016) Ting-Wei Will Chiang et al.   Scientific Reports

Nuclear transport factors: global regulation of mitosis

(2015) Douglass J Forbes et al.   CURRENT OPINION IN CELL BIOLOGY

The Biochemistry of Mitosis

(2015) Samuel Wieser et al.   Cold Spring Harbor Perspectives in Biology

Cdk1 orders mitotic events through coordination of a chromosome-associated phosphatase switch

(2015) Junbin Qian et al.   Nature Communications

Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells

(2015) Conrad von Schubert et al.   Cell Reports

Spatial control of mitotic commitment in fission yeast

(2015) Iain M. Hagan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Nuclear Pores Protect Genome Integrity by Assembling a Premitotic and Mad1-Dependent Anaphase Inhibitor

(2014) Veronica Rodriguez-Bravo et al.   CELL

Cdk1 Inactivation Terminates Mitotic Checkpoint Surveillance and Stabilizes Kinetochore Attachments in Anaphase

(2014) María Dolores Vázquez-Novelle et al.   CURRENT BIOLOGY

Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint

(2014) N. London et al.   GENES & DEVELOPMENT

A Bub1–Mad1 interaction targets the Mad1–Mad2 complex to unattached kinetochores to initiate the spindle checkpoint

(2014) Mark W. Moyle et al.   JOURNAL OF CELL BIOLOGY

Multiple mechanisms determine the order of APC/C substrate degradation in mitosis

(2014) Dan Lu et al.   JOURNAL OF CELL BIOLOGY

The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C

(2014) Daisuke Izawa et al.   NATURE

scikit-image: image processing in Python

(2014) Stéfan van der Walt et al.   PeerJ

Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis

(2013) Nina Schweizer et al.   JOURNAL OF CELL BIOLOGY

CDK-dependent phosphorylation and nuclear exclusion coordinately control kinetochore assembly state

(2013) Karen E. Gascoigne et al.   JOURNAL OF CELL BIOLOGY

The spindle assembly checkpoint works like a rheostat rather than a toggle switch

(2013) Philippe Collin et al.   NATURE CELL BIOLOGY

Electron microscopy structure of human APC/CCDH1–EMI1 reveals multimodal mechanism of E3 ligase shutdown

(2013) Jeremiah J Frye et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

(2013) Denise A McGrath et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CDK-Dependent Potentiation of MPS1 Kinase Activity Is Essential to the Mitotic Checkpoint

(2012) Violeta Morin et al.   CURRENT BIOLOGY

The Spindle Assembly Checkpoint

(2012) Pablo Lara-Gonzalez et al.   CURRENT BIOLOGY

Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C

(2012) Helene Labit et al.   EMBO JOURNAL

Condensins: universal organizers of chromosomes with diverse functions

(2012) T. Hirano   GENES & DEVELOPMENT

Mitosis-Specific Regulation of Nuclear Transport by the Spindle Assembly Checkpoint Protein Mad1p

(2012) Lucas V. Cairo et al.   MOLECULAR CELL

Centrosomal MPF triggers the mitotic and morphogenetic switches of fission yeast

(2012) Agnes Grallert et al.   NATURE CELL BIOLOGY

The Renaissance or the cuckoo clock

(2011) J. Pines et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quantitative Mass Spectrometry Analysis Reveals Similar Substrate Consensus Motif for Human Mps1 Kinase and Plk1

(2011) Zhen Dou et al.   PLoS One

Spatial Exclusivity Combined with Positive and Negative Selection of Phosphorylation Motifs Is the Basis for Context-Dependent Mitotic Signaling

(2011) J. Alexander et al.   Science Signaling

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

How cyclin A destruction escapes the spindle assembly checkpoint

(2010) Barbara Di Fiore et al.   JOURNAL OF CELL BIOLOGY

Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

(2010) Dan Liu et al.   JOURNAL OF CELL BIOLOGY

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex

(2010) Laura Hewitt et al.   JOURNAL OF CELL BIOLOGY

Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule Interface

(2010) Julie P.I. Welburn et al.   MOLECULAR CELL

The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

(2010) A. Gharbi-Ayachi et al.   SCIENCE

Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis

(2010) S. Mochida et al.   SCIENCE

Spatiotemporal control of mitosis by the conserved spindle matrix protein Megator

(2009) Mariana Lince-Faria et al.   JOURNAL OF CELL BIOLOGY

The M Phase Kinase Greatwall (Gwl) Promotes Inactivation of PP2A/B55δ, a Phosphatase Directed Against CDK Phosphosites

(2009) Priscila V. Castilho et al.   MOLECULAR BIOLOGY OF THE CELL

Role of a Novel Splice Variant of Mitotic Arrest Deficient 1 (MAD1), MAD1 , in Mitotic Checkpoint Control in Liver Cancer

(2008) K. M.-F. Sze et al.   CANCER RESEARCH

Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis

(2008) Qiang Chen et al.   CELL RESEARCH

Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint

(2008) S. H. Lee et al.   GENES & DEVELOPMENT

Positive feedback sharpens the anaphase switch

(2008) Liam J. Holt et al.   NATURE

The Jpred 3 secondary structure prediction server

(2008) C. Cole et al.   NUCLEIC ACIDS RESEARCH