The secreted protein DEL-1 activates a β3 integrin–FAK–ERK1/2–RUNX2 pathway and promotes osteogenic differentiation and bone regeneration
出版年份 2020 全文链接
标题
The secreted protein DEL-1 activates a β3 integrin–FAK–ERK1/2–RUNX2 pathway and promotes osteogenic differentiation and bone regeneration
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 295, Issue 21, Pages 7261-7273
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2020-04-13
DOI
10.1074/jbc.ra120.013024
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- DEL-1-Regulated Immune Plasticity and Inflammatory Disorders
- (2019) George Hajishengallis et al. TRENDS IN MOLECULAR MEDICINE
- Host defense against oral microbiota by bone-damaging T cells
- (2018) Masayuki Tsukasaki et al. Nature Communications
- DEL-1 promotes macrophage efferocytosis and clearance of inflammation
- (2018) Ioannis Kourtzelis et al. NATURE IMMUNOLOGY
- A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans
- (2018) Nicolas Dutzan et al. Science Translational Medicine
- Clinical association between chronic periodontitis and the leukocyte extravasation inhibitors developmental endothelial locus-1 and pentraxin-3
- (2017) Matthias Folwaczny et al. EUROPEAN JOURNAL OF ORAL SCIENCES
- Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche
- (2017) Ioannis Mitroulis et al. JOURNAL OF CLINICAL INVESTIGATION
- The extracellular matrix protein Edil3 stimulates osteoblast differentiation through the integrin α5β1/ERK/Runx2 pathway
- (2017) Sin-Hye Oh et al. PLoS One
- Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis
- (2017) David Lagares et al. Science Translational Medicine
- Resolvin E1 Reverses Experimental Periodontitis and Dysbiosis
- (2016) Chun-Teh Lee et al. JOURNAL OF IMMUNOLOGY
- Extracellular matrix mineralization in murine MC3T3-E1 osteoblast cultures: An ultrastructural, compositional and comparative analysis with mouse bone
- (2015) W.N. Addison et al. BONE
- Wnt/β-Catenin Signaling Mediates Osteoblast Differentiation Triggered by Peptide-induced α5β1 Integrin Priming in Mesenchymal Skeletal Cells
- (2015) Zuzana Saidak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Emerging Regenerative Approaches for Periodontal Reconstruction: A Systematic Review From the AAP Regeneration Workshop
- (2015) Zhao Lin et al. JOURNAL OF PERIODONTOLOGY
- Update on Prevalence of Periodontitis in Adults in the United States: NHANES 2009 to 2012
- (2015) Paul I. Eke et al. JOURNAL OF PERIODONTOLOGY
- Novel identification of matrix proteins involved in calcitic biomineralization
- (2015) Megan Rose-Martel et al. Journal of Proteomics
- Rosiglitazone inhibition of calvaria-derived osteoblast differentiation is through both of PPARγ and GPR40 and GSK3β-dependent pathway
- (2015) Xiao-Lu Tang et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Biomaterials for promoting periodontal regeneration in human intrabony defects: a systematic review
- (2015) Anton Sculean et al. PERIODONTOLOGY 2000
- DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates
- (2015) Jieun Shin et al. Science Translational Medicine
- Osteogenic differentiation of mesenchymal stem cells from dental bud: Role of integrins and cadherins
- (2015) Adriana Di Benedetto et al. Stem Cell Research
- Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway
- (2015) Tomoki Maekawa et al. Nature Communications
- The enduring importance of animal modelsin understanding periodontal disease
- (2015) George Hajishengallis et al. Virulence
- Global Burden of Severe Periodontitis in 1990-2010
- (2014) N.J. Kassebaum et al. JOURNAL OF DENTAL RESEARCH
- Proresolving Nanomedicines Activate Bone Regeneration in Periodontitis
- (2014) T.E. Van Dyke et al. JOURNAL OF DENTAL RESEARCH
- Developmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination
- (2014) E Y Choi et al. MOLECULAR PSYCHIATRY
- Integrin and cadherin signaling in bone: role and potential therapeutic targets
- (2014) Pierre J. Marie et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis
- (2014) Hai Wu et al. GENOME BIOLOGY
- Rac-Null Leukocytes Are Associated with Increased Inflammation-Mediated Alveolar Bone Loss
- (2013) Corneliu Sima et al. AMERICAN JOURNAL OF PATHOLOGY
- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- Induction of Bone Loss by Pathobiont-Mediated Nod1 Signaling in the Oral Cavity
- (2013) Yizu Jiao et al. Cell Host & Microbe
- Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes
- (2013) Daisuke Mashiko et al. DEVELOPMENT GROWTH & DIFFERENTIATION
- Resolution of inflammation: an integrated view
- (2013) Almudena Ortega-Gómez et al. EMBO Molecular Medicine
- Epidermal Growth Factor Receptor (EGFR) Signaling Promotes Proliferation and Survival in Osteoprogenitors by Increasing Early Growth Response 2 (EGR2) Expression
- (2013) Abhishek Chandra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Optimization of the ligature-induced periodontitis model in mice
- (2013) Toshiharu Abe et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Targeting integrins to promote bone formation and repair
- (2013) Pierre J. Marie Nature Reviews Endocrinology
- Prevention of inflammation-mediated bone loss in murine and canine periodontal disease via recruitment of regulatory lymphocytes
- (2013) A. J. Glowacki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin
- (2013) Ioannis Mitroulis et al. THROMBOSIS AND HAEMOSTASIS
- Extracellular matrix protein mediated regulation of the osteoblast differentiation of bone marrow derived human mesenchymal stem cells
- (2012) Smitha Mathews et al. DIFFERENTIATION
- The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss
- (2012) Mehmet A Eskan et al. NATURE IMMUNOLOGY
- Endogenous modulators of inflammatory cell recruitment
- (2012) George Hajishengallis et al. TRENDS IN IMMUNOLOGY
- Resolution of inflammation induces osteoblast function and regulates the Wnt signaling pathway
- (2011) Melissa M. Matzelle et al. ARTHRITIS AND RHEUMATISM
- Diabetes aggravates periodontitis by limiting repair through enhanced inflammation
- (2011) Sandra Pacios et al. FASEB JOURNAL
- Interactions between extracellular signal-regulated kinase 1/2 and P38 Map kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity
- (2011) Chunxi Ge et al. JOURNAL OF BONE AND MINERAL RESEARCH
- C/EBPβ binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells
- (2011) Berta Henriquez et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Extracellular matrix-mediated osteogenic differentiation of murine embryonic stem cells
- (2010) Nicholas D. Evans et al. BIOMATERIALS
- Morphological and proteomic analysis of early stage of osteoblast differentiation in osteoblastic progenitor cells
- (2010) Dun Hong et al. EXPERIMENTAL CELL RESEARCH
- Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: An in vitro model of osteoblast development
- (2010) L. Darryl Quarles et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The use of rodent models to investigate host-bacteria interactions related to periodontal diseases
- (2010) Dana T. Graves et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Integrins as therapeutic targets: lessons and opportunities
- (2010) Dermot Cox et al. NATURE REVIEWS DRUG DISCOVERY
- Oral biofilm-associated diseases: trends and implications for quality of life, systemic health and expenditures
- (2010) Thomas Beikler et al. PERIODONTOLOGY 2000
- Extracellular matrix-mediated differentiation of periodontal progenitor cells
- (2009) Smit J. Dangaria et al. DIFFERENTIATION
- MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma
- (2009) F. Marampon et al. MOLECULAR CANCER THERAPEUTICS
- Priming integrin 5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis
- (2009) Z. Hamidouche et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel aspects in the regulation of the leukocyte adhesion cascade
- (2009) Emmanouil Chavakis et al. THROMBOSIS AND HAEMOSTASIS
- Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment
- (2008) E. Y. Choi et al. SCIENCE
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