标题
It takes two (Las1 HEPN endoribonuclease domains) to cut RNA correctly
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 295, Issue 18, Pages 5857-5870
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2020-03-28
DOI
10.1074/jbc.ra119.011193
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage
- (2019) Ian M. Slaymaker et al. Cell Reports
- Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d
- (2019) Bo Zhang et al. Nature Communications
- Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex
- (2019) Monica C. Pillon et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
- (2018) Silvana Konermann et al. CELL
- Structure–function analyses reveal the molecular architecture and neutralization mechanism of a bacterial HEPN–MNT toxin–antitoxin system
- (2018) Xuanyan Jia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular Mechanisms of RNA Targeting by Cas13-containing Type VI CRISPR–Cas Systems
- (2018) Mitchell R. O'Connell JOURNAL OF MOLECULAR BIOLOGY
- Characterization of the molecular crosstalk within the essential Grc3/Las1 pre-rRNA processing complex
- (2018) Monica C. Pillon et al. RNA
- Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
- (2018) Jonathan S. Gootenberg et al. SCIENCE
- Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d
- (2018) Cheng Zhang et al. CELL
- Eurokaryotic Ribosome Assembly
- (2018) Jochen Baßler et al. Annual Review of Biochemistry
- Structural insights into Cas13b-guided CRISPR RNA maturation and recognition
- (2018) Bo Zhang et al. CELL RESEARCH
- CRISPR-Based Technologies: Impact of RNA-Targeting Systems
- (2018) Michael P. Terns MOLECULAR CELL
- Ribosome assembly coming into focus
- (2018) Sebastian Klinge et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Comparison of preribosomal RNA processing pathways in yeast, plant and human cells - focus on coordinated action of endo- and exoribonucleases
- (2017) Rafal Tomecki et al. FEBS LETTERS
- Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers
- (2017) Ole Niewoehner et al. NATURE
- Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme
- (2017) Gavin J Knott et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ensembl 2018
- (2017) Daniel R Zerbino et al. NUCLEIC ACIDS RESEARCH
- Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage
- (2017) Monica C. Pillon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA editing with CRISPR-Cas13
- (2017) David B. T. Cox et al. SCIENCE
- Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome
- (2017) Lisa Fromm et al. Nature Communications
- Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme
- (2017) Gavin J Knott et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands
- (2016) Hannah C. Feldman et al. ACS Chemical Biology
- Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
- (2016) Alexandra East-Seletsky et al. NATURE
- Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6
- (2016) Ole Niewoehner et al. RNA
- C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
- (2016) Omar O. Abudayyeh et al. SCIENCE
- Coordinated Ribosomal ITS2 RNA Processing by the Las1 Complex Integrating Endonuclease, Polynucleotide Kinase, and Exonuclease Activities
- (2015) Lisa Gasse et al. MOLECULAR CELL
- X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes
- (2015) H Hu et al. MOLECULAR PSYCHIATRY
- Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity
- (2014) Hao Huang et al. MOLECULAR CELL
- Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis
- (2014) R. J. Butterfield et al. NEUROLOGY
- Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response
- (2014) Y. Han et al. SCIENCE
- Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing
- (2013) Vivek Anantharaman et al. Biology Direct
- Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae
- (2013) John L. Woolford et al. GENETICS
- Crystal structure and nucleic acid-binding activity of the CRISPR-associated protein Csx1 ofPyrococcus furiosus
- (2013) Young Kwan Kim et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Las1 interacts with Grc3 polynucleotide kinase and is required for ribosome synthesis in Saccharomyces cerevisiae
- (2012) Christopher D. Castle et al. NUCLEIC ACIDS RESEARCH
- Structural and functional basis for RNA cleavage by Ire1
- (2011) Alexei V Korennykh et al. BMC BIOLOGY
- The Evolutionarily Conserved Protein LAS1 Is Required for Pre-rRNA Processing at Both Ends of ITS2
- (2011) S. Schillewaert et al. MOLECULAR AND CELLULAR BIOLOGY
- Nol9 is a novel polynucleotide 5′-kinase involved in ribosomal RNA processing
- (2010) Katrin Heindl et al. EMBO JOURNAL
- Las1L Is a Nucleolar Protein Required for Cell Proliferation and Ribosome Biogenesis
- (2010) C. D. Castle et al. MOLECULAR AND CELLULAR BIOLOGY
- Nucleases: diversity of structure, function and mechanism
- (2010) Wei Yang QUARTERLY REVIEWS OF BIOPHYSICS
- Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae
- (2009) Marie-Ange Teste et al. BMC MOLECULAR BIOLOGY
- Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing
- (2008) Kenneth P.K. Lee et al. CELL
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