Article
Radiology, Nuclear Medicine & Medical Imaging
Jiseon Oh, Jung-Eun Cheon, Junghoan Park, Young Hun Choi, Yeon Jin Cho, Seunghyun Lee, Seung Ha Oh, Su-Mi Shin, Sun-Won Park
Summary: Preoperative CT can reliably determine cochlear size and distances. Distance A can be used as a predictive marker for estimating insertion depth angle during CI surgery.
EUROPEAN RADIOLOGY
(2021)
Article
Audiology & Speech-Language Pathology
Randy K. Kalkman, Jeroen J. Briaire, David M. T. Dekker, Johan H. M. Frijns
Summary: The study aims to test the hypothesis that sensitivity to cochlear implant stimulation polarity can be interpreted as a measure of neural health. The computational modelling study explores the effects of stimulus polarity on neural excitation patterns and concludes that polarity sensitivity is not a reliable indicator of neural health.
Article
Multidisciplinary Sciences
C. Riemann, L. U. Scholtz, H. B. Gehl, M. Schuermann, H. Sudhoff, I. Todt
Summary: The study evaluated the position of cochlear implant electrodes using 3T MRI scanning, demonstrating that MRI allows accurate determination of the electrode position in the inner ear, providing important information for quality control.
SCIENTIFIC REPORTS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Iris Burck, Rania A. Helal, Nagy N. N. Naguib, Nour-Eldin A. Nour-Eldin, Jan-Erik Scholtz, Simon Martin, Martin Leinung, Silke Helbig, Timo Stoever, Annette Lehn, Thomas J. Vogl
Summary: The study found that postoperative facial nerve stimulation was not significantly correlated with mastoid facial canal diameter, wall thickness, distance to CI cable, and angle with chorda tympani, but significantly associated with a history of meningitis/encephalitis, extracochlear-electrode-contacts, scala-vestibuli position, younger patient age, lateral-wall-electrode type, and early onset hearing loss.
EUROPEAN RADIOLOGY
(2022)
Article
Engineering, Biomedical
Alena-Kathrin Golla, Dominik F. Bauer, Ralf Schmidt, Tom Russ, Dominik Norenberg, Khanlian Chung, Christian Toennes, Lothar R. Schad, Frank G. Zoellner
Summary: The study presents an automatic method for extracting and differentiating abdominal blood vessel trees using convolutional neural networks (CNNs), achieving high accuracy and generalizability. Ensemble networks outperform individual CNNs and surpass state-of-the-art methods in segmentation of vascular structures.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Biochemical Research Methods
Angel Ramos-de-Miguel, Jose M. Escobar, David Greiner, Domingo Benitez, Eduardo Rodriguez, Albert Oliver, Marcos Hernandez, Angel Ramos-Macias
Summary: There is a growing interest in biomedical engineering in developing procedures that provide accurate simulations of the neural response to electrical stimulus produced by implants. Recent research focuses on models that take into account individual patient characteristics. The authors present a computational model that uses the patient's data to simulate the neural response to electrical stimulus produced by cochlear implants (CIs). The model considers input currents and uses the finite element method (FEM) to calculate potentials and currents. The model is validated with real data from two patients and shows a satisfactory fit.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Behavioral Sciences
Ladan Zamaninezhad, Berkutay Mert, Heval Benav, Jochen Tillein, Carolyn Garnham, Uwe Baumann
Summary: This study found that there is a significant correlation between IPGE(slope) and speech perception in both quiet and noise when considering the relative importance of each frequency band. The polarity of the stimulating pulse can influence the diagnostic potential of IPGE(slope).
FRONTIERS IN INTEGRATIVE NEUROSCIENCE
(2023)
Article
Clinical Neurology
Faizah Mushtaq, Andrew Soulby, Patrick Boyle, Terry Nunn, Douglas E. H. Hartley
Summary: Recent technological advances in CI telemetry have allowed CI users to assess their cochlear health (CH) through self-assessment. This study evaluated the feasibility of using a CI to assess CH and found that electrode impedances and eCAPs are promising measurements for objectively assessing CH.
FRONTIERS IN NEUROLOGY
(2022)
Article
Engineering, Biomedical
Mingwei Zhai, Yong Yang, Fangfang Sun, Xinhui Wang, Xiaozhuang Wang, Changjie Ke, Chenhao Yu, Hongwei Ye
Summary: The study aims to generate T2CT images from delayed PET (T2PET), regular PET (T1PET), and regular CT (T1CT) images using deep learning methods. The multi-resolution registration convolutional neural network (MRR-CNN) is introduced to improve the accuracy of generating CT images.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Angela T. Li, Peter B. Noel, Nadav Shapira
Summary: This study aimed to use artificial intelligence algorithms to automate the bolus tracking procedure in contrast-enhanced abdominal CT exams, in order to improve standardization and diagnostic accuracy while simplifying the imaging workflow. The results showed that the automatic locator scan network offered improved positional consistency compared to manual slice positionings, and demonstrated that inter-operator variance is an important source of error.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Engineering, Biomedical
A. S. Neethi, S. Niyas, Santhosh Kumar Kannath, Jimson Mathew, Ajimi Mol Anzar, Jeny Rajan
Summary: This study proposes a model for diagnosing stroke from CT scans, addressing the challenges of limited training samples and class imbalance. The proposed method achieves significant improvement in stroke classification compared to the state-of-the-art models.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2022)
Article
Audiology & Speech-Language Pathology
David P. Herrmann, Katharina V. A. Kretzer, Sabrina H. Pieper, Andreas Bahmer
Summary: The study investigated the impact of polarity distribution on neuronal stimulation, finding that the difference in temporal polarity distribution had a smaller effect on the ECAP response with anodic second phase. However, the effect on psychophysical detection thresholds was similar for both polarities.
Article
Health Care Sciences & Services
Bingjiang Qiu, Hylke van der Wel, Joep Kraeima, Haye Hendrik Glas, Jiapan Guo, Ronald J. H. Borra, Max Johannes Hendrikus Witjes, Peter M. A. van Ooijen
Summary: A novel coarse-to-fine segmentation framework based on 3D convolutional neural network and recurrent SegUnet is proposed for mandible segmentation in CBCT scans. The method decomposes mandible segmentation into two stages: localization of mandible-like regions by rough segmentation and further accurate segmentation of mandible details.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
H. O. Tekin, Faisal Almisned, T. T. Erguzel, Mohamed M. Abuzaid, W. Elshami, Antoaneta Ene, Shams A. M. Issa, Hesham M. H. Zakaly
Summary: This study evaluated the use of Artificial Neural Network (ANN) modeling to estimate the dose length product (DLP) value during abdominal CT examinations for quality assurance. The results showed that the Levenberg-Marquardt algorithm comprehensively detects DLP values and can simplify CT quality assurance. The study concluded that this artificial intelligence method can be used for accurate DLP estimations in high radiation risk situations or when risk evaluation of multiple CT scans is needed.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Aniek T. Zwart, Vitor J. Cavalheiro, Maria J. Lamers, Rudi A. J. O. Dierckx, Geertruida H. de Bock, Gyorgy B. Halmos, Anouk van der Hoorn
Summary: The study found that low-dose neck CT scans from [F-18]-FDG PET-CT can provide comparable results to diagnostic neck CT scans in head and neck cancer patients. This enables SMI analysis in patients without a diagnostic neck CT but with a [F-18]-FDG PET-CT scan.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Neurosciences
Robert P. Carlyon, Francois Guerit, John M. Deeks, Andrew Harland, Robin Gransier, Jan Wouters, Simone R. de Rijk, Manohar Bance
Summary: This study measured the sustained neural response to electrical stimulation by a cochlear implant, showing the presence of neural distortion response. Different frequencies of stimuli resulted in varying degrees of neural nonlinearity.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2021)
Article
Audiology & Speech-Language Pathology
Robin Gransier, Francois Guerit, Robert P. Carlyon, Jan Wouters
Summary: This study investigated the feasibility of measuring electrophysiological responses in cochlear implant users to understand temporal processing limitations in the electrically-stimulated auditory pathway. Using a high-sampling rate EEG system, the researchers were able to measure neural responses in CI users and remove stimulation artifacts through linear interpolation. The results suggest that it is possible to measure electrophysiological responses free from stimulation artifacts, which could potentially be used as neural correlates for rate and pitch processing in CI users.
Article
Audiology & Speech-Language Pathology
Laurent Demany, Guilherme Monteiro, Catherine Semal, Shihab Shamma, Robert P. Carlyon
Summary: The perception of octave pitch affinity has a biological basis and listeners are more efficient at detecting mistunings in the harmonic condition, where tones fuse into a single sound percept.
Article
Acoustics
Hedwig E. Gockel, Robert P. Carlyon
Summary: The study found that listeners were able to adjust various musical intervals even when all harmonic frequencies were above the limit of phase locking, although performance was significantly worse. This may be attributed to familiarity with high-frequency stimuli and the possible effects of phase-locking information on pitch perception.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2021)
Review
Neurosciences
Robert P. Carlyon, Tobias Goehring
Summary: Cochlear implants have been the focus of intense research and development, leading to significant improvements in patient outcomes. Advances in processing, stimulation, and audiological methods have contributed to enhancing speech perception in CI users, indicating potential for further progress in the field.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2021)
Article
Acoustics
Hedwig E. E. Gockel, Robert P. P. Carlyon
Summary: This study assessed the detection of mistuning of a single harmonic in complex tones and found that phase locking to the temporal fine structure is crucial for perceptual segregation and the corresponding beat perception.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2022)
Article
Neurosciences
Francois Guerit, Andrew J. Harland, Matthew L. Richardson, Robin Gransier, John C. Middlebrooks, Jan Wouters, Robert P. Carlyon
Summary: To investigate the perception of pitch, we presented harmonic complexes to normal-hearing listeners, with different pulse rates and frequency ranges. We measured the brainstem and cortical processing using the frequency following response (FFR) and auditory change complex (ACC), respectively. We found that the ACC may serve as a reliable surrogate for behavioral measures of rate discrimination, and the rate difference limens (DLs) increased when the baseline rate was reduced.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2023)
Article
Neurosciences
Francois Guerit, John M. Deeks, Dorothee Arzounian, Robin Gransier, Jan Wouters, Robert P. Carlyon
Summary: Two EEG experiments investigated the neural response to amplitude-modulated pulse trains presented to a cochlear-implant electrode. Results showed a neural distortion response at a specific frequency, indicating the presence of temporal dependencies and neural nonlinearities. The findings suggest that the neural response can be used as an objective estimate of the most comfortable level.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2023)
Article
Acoustics
Alan W. W. Archer-Boyd, Andrew Harland, Tobias Goehring, Robert P. P. Carlyon
Summary: The STRIPES test is used to measure spectro-temporal resolution in cochlear-implant (CI) listeners. This article investigates the suitability of an online application, webSTRIPES, as a remote test. The results show a strong correlation in STRIPES thresholds between laboratory testing and remote testing, with no significant difference.
JASA EXPRESS LETTERS
(2023)
Article
Neurosciences
Francois Guerit, John C. Middlebrooks, Matthew L. Richardson, Akshat Arneja, Andrew J. Harland, Robin Gransier, Jan Wouters, Robert P. Carlyon
Summary: This study introduces a scalp-recorded measure of tonotopic selectivity called the cortical onset response (COR) and compares the results between humans and cats. The COR results are found to be similar to the psychophysical masked-detection thresholds in both species, although there are some subtle differences.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2022)
Article
Engineering, Biomedical
Chen Jiang, Shreya Singhal, Thomas Landry, Iwan Roberts, Simone R. de Rijk, Tim Brochier, Tobias Goehring, Yu Tam, Robert Carlyon, George Malliaras, Manohar Bance
Summary: Researchers simulated and compared electrical current spread under different stimulation modes using a 3D-printed physical cochlea model with integrated sensing wires. The results show a trade-off between stimulation amplitude and current focusing among different stimulation modes.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Neurosciences
Tim Brochier, Colette M. McKay, Robert P. Carlyon
Summary: This study examines the impact of stimulation parameters on the representation of sounds by cochlear implants, proposing a theoretical model and reanalyzing relevant data. The findings suggest that the current methods of data analysis do not effectively distinguish between neural and non-neural factors affecting sound representation.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2021)
Article
Neurosciences
Tim Brochier, Francois Guerit, John M. Deeks, Charlotte Garcia, Manohar Bance, Robert P. Carlyon
Summary: The study evaluated and compared different measures of neural health in cochlear implant users, finding that there were no significant correlations between the different estimates. The results suggest that measures such as multipulse integration, polarity effect, and interphase gap offset may reflect different characteristics of the electrode-neural interface.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2021)
Article
Audiology & Speech-Language Pathology
Alan W. Archer-Boyd, Tobias Goehring, Robert P. Carlyon
Article
Acoustics
Hedwig E. Gockel, Brian C. J. Moore, Robert P. Carlyon
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2020)