Copper Oxide Nanoparticles Induce Oxidative DNA Damage and Cell Death via Copper Ion-Mediated P38 MAPK Activation in Vascular Endothelial Cells

Lysosomal deposition of copper oxide nanoparticles triggers HUVEC cells death

(2018) Jun Zhang et al.   BIOMATERIALS

Transcriptional responses and mechanisms of copper nanoparticle toxicology on zebrafish embryos

(2018) YanJun Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Copper nanoparticles induce early fibrotic changes in the liver via TGF-β/Smad signaling and cause immunosuppressive effects in rats

(2018) In-Chul Lee et al.   Nanotoxicology

Copper oxide nanoparticles induce collagen deposition via TGF-β1/Smad3 signaling in human airway epithelial cells

(2018) Je-Won Ko et al.   Nanotoxicology

Autophagy-dependent release of zinc ions is critical for acute lung injury triggered by zinc oxide nanoparticles

(2018) Xuejun Jiang et al.   Nanotoxicology

Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells

(2017) Jun Zhang et al.   Cell Death & Disease

Copper toxicology, oxidative stress and inflammation using zebrafish as experimental model

(2016) Talita Carneiro Brandão Pereira et al.   JOURNAL OF APPLIED TOXICOLOGY

Where does the toxicity of metal oxide nanoparticles come from: The nanoparticles, the ions, or a combination of both?

(2016) Dali Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Mechanistical investigation on the self-enhanced photocatalytic activity of CuO/Cu2O hybrid nanostructures by density functional theory calculations

(2016) Feiyu Diao et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Cell Signaling and Stress Responses

(2016) Gökhan S. Hotamisligil et al.   Cold Spring Harbor Perspectives in Biology

Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells

(2016) Amaraporn Wongrakpanich et al.   Environmental Science-Nano

Air Pollution and Cardiovascular Disease

(2015) Barry A. Franklin et al.   CURRENT PROBLEMS IN CARDIOLOGY

Elevated copper impairs hepatic nuclear receptor function in Wilson’s disease

(2015) Clavia Ruth Wooton-Kee et al.   JOURNAL OF CLINICAL INVESTIGATION

Copper oxide nanoparticles aggravate airway inflammation and mucus production in asthmatic mice via MAPK signaling

(2015) Ji-Won Park et al.   Nanotoxicology

Copper-based nanoparticles induce high toxicity in leukemic HL60 cells

(2015) Ylva Rodhe et al.   TOXICOLOGY IN VITRO

Toxicity of copper oxide nanoparticles in lung epithelial cells exposed at the air–liquid interface compared with in vivo assessment

(2015) Xuefang Jing et al.   TOXICOLOGY IN VITRO

Toxic mechanisms of copper oxide nanoparticles in epithelial kidney cells

(2015) Amalie Thit et al.   TOXICOLOGY IN VITRO

CuO nanoparticles induce apoptosis by impairing the antioxidant defense and detoxification systems in the mouse hippocampal HT22 cell line: Protective effect of crocetin

(2015) Karolina Niska et al.   TOXICOLOGY IN VITRO

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression

(2014) Chengzhi Chen et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Interplay between autophagy and apoptosis mediated by copper oxide nanoparticles in human breast cancer cells MCF7

(2013) Dipranjan Laha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Uptake and toxicity of copper oxide nanoparticles in cultured primary brain astrocytes

(2013) Felix Bulcke et al.   Nanotoxicology

Oxidative stress induced by inorganic nanoparticles in bacteria and aquatic microalgae – state of the art and knowledge gaps

(2013) Nadia von Moos et al.   Nanotoxicology

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)

(2012) Vyom Sharma et al.   APOPTOSIS

DNA Damage Caused by Metal Nanoparticles: Involvement of Oxidative Stress and Activation of ATM

(2012) Rong Wan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nuclear Localization of p38 MAPK in Response to DNA Damage

(2012) C. David Wood et al.   International Journal of Biological Sciences

Copper(ii) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response

(2012) Jean-Pascal Piret et al.   Nanoscale

Copper Oxide Nanoparticles Induce Autophagic Cell Death in A549 Cells

(2012) Tingting Sun et al.   PLoS One

Molecular Responses of Human Lung Epithelial Cells to the Toxicity of Copper Oxide Nanoparticles Inferred from Whole Genome Expression Analysis

(2011) Nobutaka Hanagata et al.   ACS Nano

Copper: An essential metal in biology

(2011) Richard A. Festa et al.   CURRENT BIOLOGY

Gold Nanoparticles Promote Osteogenic Differentiation of Mesenchymal Stem Cells through p38 MAPK Pathway

(2010) Changqing Yi et al.   ACS Nano

Contribution of physicochemical characteristics of nano-oxides to cytotoxicity

(2010) Mingsheng Xu et al.   BIOMATERIALS

One-Dimensional Oxide Nanostructures as Gas-Sensing Materials: Review and Issues

(2010) Kyoung Jin Choi et al.   SENSORS

Copper in Alzheimer’s disease: too much or too little?

(2009) Joseph F Quinn et al.   Expert Review of Neurotherapeutics

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes

(2008) Hanna L. Karlsson et al.   CHEMICAL RESEARCH IN TOXICOLOGY