Assessing the Cognitive Translational Potential of a Mouse Model of the 22q11.2 Microdeletion Syndrome

A mouse model of the 15q13.3 microdeletion syndrome shows prefrontal neurophysiological dysfunctions and attentional impairment

(2016) Simon R. O. Nilsson et al.   PSYCHOPHARMACOLOGY

Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder

(2015) J. H. Kogan et al.   JOURNAL OF NEUROSCIENCE

Trial-unique, delayed nonmatching-to-location (TUNL) touchscreen testing for mice: sensitivity to dorsal hippocampal dysfunction

(2015) Chi Hun Kim et al.   PSYCHOPHARMACOLOGY

The NEWMEDS rodent touchscreen test battery for cognition relevant to schizophrenia

(2015) M. Hvoslef-Eide et al.   PSYCHOPHARMACOLOGY

Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome

(2014) Maude Schneider et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Ultimate Intra-/Extra-Dimensional Attentional Set-Shifting Task for Mice

(2013) Diego Scheggia et al.   BIOLOGICAL PSYCHIATRY

Cognitive Ability is Associated with Altered Medial Frontal Cortical Circuits in the LgDel Mouse Model of 22q11.2DS

(2013) D. W. Meechan et al.   CEREBRAL CORTEX

Temporally distinct cognitive effects following acute administration of ketamine and phencyclidine in the rat

(2013) Francois Gastambide et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Phenotype of mice with inducible ablation of GluA1 AMPA receptors during late adolescence: Relevance for mental disorders

(2013) Dragos Inta et al.   HIPPOCAMPUS

The Pattern of Cortical Dysfunction in a Mouse Model of a Schizophrenia-Related Microdeletion

(2013) K. Fenelon et al.   JOURNAL OF NEUROSCIENCE

Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion

(2013) J Ellegood et al.   MOLECULAR PSYCHIATRY

The touchscreen operant platform for assessing executive function in rats and mice

(2013) Adam C Mar et al.   Nature Protocols

The touchscreen operant platform for testing working memory and pattern separation in rats and mice

(2013) Charlotte A Oomen et al.   Nature Protocols

The touchscreen operant platform for testing learning and memory in rats and mice

(2013) Alexa E Horner et al.   Nature Protocols

Dissociation between memory retention across a delay and pattern separation following medial prefrontal cortex lesions in the touchscreen TUNL task

(2013) Kathryn A.L. McAllister et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Cognitive components in mice and humans: Combining genetics and touchscreens for medical translation

(2013) Jess Nithianantharajah et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Stress in Puberty Unmasks Latent Neuropathological Consequences of Prenatal Immune Activation in Mice

(2013) S. Giovanoli et al.   SCIENCE

Altered Development of the Dorsolateral Prefrontal Cortex in Chromosome 22q11.2 Deletion Syndrome: An In Vivo Proton Spectroscopy Study

(2012) Vandana Shashi et al.   BIOLOGICAL PSYCHIATRY

TNiK Is Required for Postsynaptic and Nuclear Signaling Pathways and Cognitive Function

(2012) M. P. Coba et al.   JOURNAL OF NEUROSCIENCE

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior

(2012) Tomás J Ryan et al.   NATURE NEUROSCIENCE

Synaptic scaffold evolution generated components of vertebrate cognitive complexity

(2012) Jess Nithianantharajah et al.   NATURE NEUROSCIENCE

Standardizing the use of the Continuous Performance Test in schizophrenia research: A validation study

(2012) Phoebe V. Kahn et al.   SCHIZOPHRENIA RESEARCH

Selective overexpression of Comt in prefrontal cortex rescues schizophrenia-like phenotypes in a mouse model of 22q11 deletion syndrome

(2012) S Kimoto et al.   Translational Psychiatry

Impaired Attention in the 3xTgAD Mouse Model of Alzheimer's Disease: Rescue by Donepezil (Aricept)

(2011) C. Romberg et al.   JOURNAL OF NEUROSCIENCE

Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion

(2011) Liam J. Drew et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Paradoxical reversal learning enhancement by stress or prefrontal cortical damage: rescue with BDNF

(2011) Carolyn Graybeal et al.   NATURE NEUROSCIENCE

Intact attentional processing but abnormal responding in M1 muscarinic receptor-deficient mice using an automated touchscreen method

(2011) Susan J. Bartko et al.   NEUROPHARMACOLOGY

Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?

(2011) Chris Barkus et al.   NEUROPHARMACOLOGY

New translational assays for preclinical modelling of cognition in schizophrenia: The touchscreen testing method for mice and rats

(2011) T.J. Bussey et al.   NEUROPHARMACOLOGY

Proton Magnetic Resonance Spectroscopy in 22q11 Deletion Syndrome

(2011) Fabiana da Silva Alves et al.   PLoS One

Dysregulation of Presynaptic Calcium and Synaptic Plasticity in a Mouse Model of 22q11 Deletion Syndrome

(2010) L. R. Earls et al.   JOURNAL OF NEUROSCIENCE

Impaired hippocampal–prefrontal synchrony in a genetic mouse model of schizophrenia

(2010) Torfi Sigurdsson et al.   NATURE

Trial-unique, delayed nonmatching-to-location (TUNL): A novel, highly hippocampus-dependent automated touchscreen test of location memory and pattern separation

(2010) J.C. Talpos et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Assessing cognitive function in clinical trials of schizophrenia

(2010) Jennifer H. Barnett et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A computer-automated touchscreen paired-associates learning (PAL) task for mice: impairments following administration of scopolamine or dicyclomine and improvements following donepezil

(2010) Susan J. Bartko et al.   PSYCHOPHARMACOLOGY

Prepulse inhibition and genetic mouse models of schizophrenia

(2009) Susan B. Powell et al.   BEHAVIOURAL BRAIN RESEARCH

Discrimination Learning, Reversal, and Set-Shifting in First-Episode Schizophrenia: Stability Over Six Years and Specific Associations with Medication Type and Disorganization Syndrome

(2009) Verity C. Leeson et al.   BIOLOGICAL PSYCHIATRY

Pharmacological or Genetic Inactivation of the Serotonin Transporter Improves Reversal Learning in Mice

(2009) J. L. Brigman et al.   CEREBRAL CORTEX

Psychiatric Disorders and Intellectual Functioning Throughout Development in Velocardiofacial (22q11.2 Deletion) Syndrome

(2009) Tamar Green et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

(2009) Juan E Belforte et al.   NATURE NEUROSCIENCE

Dopamine Modulates Persistent Synaptic Activity and Enhances the Signal-to-Noise Ratio in the Prefrontal Cortex

(2009) Sven Kroener et al.   PLoS One

Evidence of gray matter reduction and dysfunction in chromosome 22q11.2 deletion syndrome

(2009) Vandana Shashi et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

A novel touchscreen-automated paired-associate learning (PAL) task sensitive to pharmacological manipulation of the hippocampus: a translational rodent model of cognitive impairments in neurodegenerative disease

(2009) J. C. Talpos et al.   PSYCHOPHARMACOLOGY

Genetic Dissection of the Role of Catechol-O-Methyltransferase in Cognition and Stress Reactivity in Mice

(2008) F. Papaleo et al.   JOURNAL OF NEUROSCIENCE

Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit

(2008) J. L. Brigman et al.   LEARNING & MEMORY

Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model

(2008) Kimberly L Stark et al.   NATURE GENETICS

Excitotoxic lesions restricted to the dorsal CA1 field of the hippocampus impair spatial memory and extinction learning in C57BL/6 mice

(2008) Gregory M. Dillon et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Object recognition memory: Neurobiological mechanisms of encoding, consolidation and retrieval

(2008) Boyer D. Winters et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat prefrontal cortex

(2008) C. C. Lapish et al.   PSYCHOPHARMACOLOGY