期刊
CERAMICS INTERNATIONAL
卷 42, 期 12, 页码 13670-13681出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ceramint.2016.05.165
关键词
Calcium phosphate cement; Wollastonite; Setting behavior; Compressive strength; Osteogenic differentiation
资金
- National Natural Science Foundation of China, China [51172074]
- National High Technology Research and Development Program of China [2015AA033601]
- Science and Technology Program of Guangzhou City of China [201508020017]
- Foundation for the Author of the Excellent Doctoral Dissertation of Guangdong Province [sybzzxm 201024]
In this study, a calcium phosphate-based composite cement was fabricated by incorporating wollastonite (WS) into calcium phosphate cement (CPC). The setting behavior, microstructure, injectability, porosity, compressive strength, anti-washout property, in vitro degradation, and cell behavior of the WS/CPC composite cement were systematically investigated. The results revealed that the addition of WS promoted the hydration reaction but without affecting the hydration product of CPC. The injectability of the WS/CPC composite cement declined with the incorporation of WS to a certain extent, especially when the content of WS was higher than 20 wt%. By incorporating appropriate amount of WS into CPC, the composite cement obtained feasible setting time, enhanced compressive strength, improved anti washout performance, and favorable biocompatibility. On the basis of its improved comprehensive application -relevant properties, the WS/CPC composite cement is prospective to be a promising biomaterial for bone defect repairing. (C) 2016 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据