4.8 Editorial Material

A Tuft Act to Follow: Leukotrienes Take the Stage in Anti-worm Immunity

期刊

IMMUNITY
卷 52, 期 3, 页码 426-428

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CELL PRESS
DOI: 10.1016/j.immuni.2020.02.011

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资金

  1. Stanford School of Medicine Dean's Postdoctoral Fellowship
  2. Jacob Churg Award
  3. National Institutes of Health (NIH) [K01DK113041]

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Tuft cells are specialized taste-chemosensory cells that detect the presence of intestinal parasites and orchestrate type 2 immunity. In this issue of Immunity, McGinty et al. discover that parasitic worms, but not commensal protists, stimulate tuft cells to release cysteinyl leukotrienes to amplify anti-helminth immunity in the small intestine.

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