‘Mini’ U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects

Long Terminal Repeat CRISPR-CAR-Coupled “Universal” T Cells Mediate Potent Anti-leukemic Effects

(2018) Christos Georgiadis et al.   MOLECULAR THERAPY

The life of U6 small nuclear RNA, from cradle to grave

(2018) Allison L. Didychuk et al.   RNA

RNA Polymerase II Activity of Type 3 Pol III Promoters

(2018) Zongliang Gao et al.   Molecular Therapy-Nucleic Acids

Nucleosome Positioning and NDR Structure at RNA Polymerase III Promoters

(2017) Alexandra Søgaard Helbo et al.   Scientific Reports

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

(2016) Britt Adamson et al.   CELL

Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition

(2016) Jiangtao Ren et al.   CLINICAL CANCER RESEARCH

MicroRNAs and human retroviruses

(2011) Laurent Houzet et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Mechanism of Reduction in Titers From Lentivirus Vectors Carrying Large Inserts in the 3′LTR

(2009) Fabrizia Urbinati et al.   MOLECULAR THERAPY

Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice

(2009) Ryan L Boudreau et al.   MOLECULAR THERAPY

Bidirectional promoter interference between two widely used internal heterologous promoters in a late-generation lentiviral construct

(2008) J A Curtin et al.   GENE THERAPY

Lentiviral Vector Design for Multiple shRNA Expression and Durable HIV-1 Inhibition

(2008) Olivier ter Brake et al.   MOLECULAR THERAPY

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

(2008) J. L. McBride et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

(2008) M. D. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA