Nonenzymatic oxygenated metabolite of docosahexaenoic acid, 4(RS )-4-F4t -neuroprostane, acts as a bioactive lipid molecule in neuronal cells

Increase in omega-6 and decrease in omega-3 polyunsaturated fatty acid oxidation elevates the risk of exudative AMD development in adults with Chinese diet

(2019) Ho Hang Leung et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protectin DX attenuates LPS-induced inflammation and insulin resistance in adipocytes via AMPK-mediated suppression of the NFκB pathway

(2018) Tae Woo Jung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Relevance of 4-F 4t -neuroprostane and 10-F 4t -neuroprostane to neurological diseases

(2018) Cinzia Signorini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Non-enzymatic oxidized metabolite of DHA, 4( RS )-4-F 4t -neuroprostane protects the heart against reperfusion injury

(2017) Jérôme Roy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protectin DX increases survival in a mouse model of sepsis by ameliorating inflammation and modulating macrophage phenotype

(2017) Haifa Xia et al.   Scientific Reports

Development of an LC-MS/MS analytical method for the simultaneous measurement of aldehydes from polyunsaturated fatty acids degradation in animal feed

(2016) Caroline Douny et al.   Drug Testing and Analysis

Non-enzymatic cyclic oxygenated metabolites of adrenic, docosahexaenoic, eicosapentaenoic and α-linolenic acids; bioactivities and potential use as biomarkers

(2015) Jean-Marie Galano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Nonenzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid

(2015) Jérôme Roy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Special Issue on “Analytical Methods for Oxidized Biomolecules and Antioxidants” The use of isoprostanoids as biomarkers of oxidative damage, and their role in human dietary intervention studies

(2015) J.-M. Galano et al.   FREE RADICAL RESEARCH

Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation

(2015) Jérôme Roy et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Synthesis, Discovery, and Quantitation of Dihomo-Isofurans: Biomarkers for In Vivo Adrenic Acid Peroxidation

(2014) Aurélien de La Torre et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Syntheses and In Vivo Quantitation of Novel Neurofuran and Dihomo-isofuran Derived from Docosahexaenoic Acid and Adrenic Acid

(2014) Aurélien de la Torre et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxygenated Metabolites ofn-3 Polyunsaturated Fatty Acids as Potential Oxidative Stress Biomarkers: Total Synthesis of 8-F3t-IsoP, 10-F4t-NeuroP and [D4]-10-F4t-NeuroP

(2014) Alexandre Guy et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cerebrospinal fluid biomarkers for neuropsychological symptoms in early stage of late-onset Alzheimer's disease

(2014) Hung-Chou Kuo et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Omega-3 Fatty Acids Protect the Brain against Ischemic Injury by Activating Nrf2 and Upregulating Heme Oxygenase 1

(2014) M. Zhang et al.   JOURNAL OF NEUROSCIENCE

Total Synthesis of Neuroprotectin D1 Analogues Derived from Omega-6 Docosapentaenoic Acid (DPA) and Adrenic Acid (AdA) from a Common Pivotal, Late-Stage Intermediate

(2014) Gandrath Dayaker et al.   JOURNAL OF ORGANIC CHEMISTRY

Isoprostanes and Neuroprostanes as Biomarkers of Oxidative Stress in Neurodegenerative Diseases

(2014) Elżbieta Miller et al.   Oxidative Medicine and Cellular Longevity

Protectin DX, a Double Lipoxygenase Product of DHA, Inhibits Both ROS Production in Human Neutrophils and Cyclooxygenase Activities

(2013) Miao Liu et al.   LIPIDS

4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation

(2013) Atsushi Ishikado et al.   PLoS One

Isoprostanes and neuroprostanes: Total synthesis, biological activity and biomarkers of oxidative stress in humans

(2013) Jean-Marie Galano et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function

(2012) Elizabeth Gray et al.   Journal of Neuroinflammation

Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells

(2010) Atsushi Ishikado et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Handy Use of Brown’s P2-Ni Catalyst for a Skipped Diyne Deuteration: Application to the Synthesis of a [D4]-Labeled F4t-Neuroprostane

(2010) Camille Oger et al.   CHEMISTRY-A EUROPEAN JOURNAL

Human Catalase Gene is Regulated by Peroxisome Proliferator Activated Receptor-gamma through a Response Element Distinct from That of Mouse

(2010) Yosuke OKUNO et al.   ENDOCRINE JOURNAL

Poxytrins, a class of oxygenated products from polyunsaturated fatty acids, potently inhibit blood platelet aggregation

(2010) Ping Chen et al.   FASEB JOURNAL

Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression

(2010) Melissa A. Bradley et al.   NEUROBIOLOGY OF AGING

Docosahexaenoic acid metabolome in neural tumors: identification of cytotoxic intermediates

(2009) Helena Gleissman et al.   FASEB JOURNAL

Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation

(2009) P. Chen et al.   FEBS LETTERS

Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes)in Vivofrom Eicosapentaenoic Acid

(2008) Joshua D. Brooks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE