Further exploration of DVD-445 as a lead thioredoxin reductase (TrxR) inhibitor for cancer therapy: Optimization of potency and evaluation of anticancer potential
Further exploration of DVD-445 as a lead thioredoxin reductase (TrxR) inhibitor for cancer therapy: Optimization of potency and evaluation of anticancer potential
作者
关键词
Oxidative stress, Cancer cell defense mechanism, Thioredoxin reductase, Covalent inhibitor, Michael acceptors, Ugi four-component reaction, P-gp inhibition
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