Ten-Eleven Translocation 1 and 2 Confer Overlapping Transcriptional Programs for the Proliferation of Cultured Adult Neural Stem Cells

TET1 contributes to neurogenesis onset time during fetal brain development in mice

(2016) Hyerim Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Paradox of pattern separation and adult neurogenesis: A dual role for new neurons balancing memory resolution and robustness

(2016) Stephen T. Johnston et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

A Novel Function of TET2 in CNS: Sustaining Neuronal Survival

(2015) Yajing Mi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation

(2015) Laura Wiehle et al.   MOLECULAR AND CELLULAR BIOLOGY

A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands

(2015) Robert E. Johnson et al.   MOLECULAR CELL

TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues

(2015) Francesco Neri et al.   NUCLEIC ACIDS RESEARCH

Adult hippocampal neural stem and progenitor cells regulate the neurogenic niche by secreting VEGF

(2015) Elizabeth D. Kirby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice

(2015) Zhigang Zhao et al.   Cell Reports

Epigenetic regulation of stemness maintenance in the neurogenic niches

(2015) Raquel Montalbán-Loro   World Journal of Stem Cells

TET1 is a tumour suppressor that inhibits colon cancer growth by derepressing inhibitors of the WNT pathway

(2014) F Neri et al.   ONCOGENE

Suppression of TET1-Dependent DNA Demethylation Is Essential for KRAS-Mediated Transformation

(2014) Bo-Kuan Wu et al.   Cell Reports

Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition

(2013) Run-Rui Zhang et al.   Cell Stem Cell

Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development

(2013) Meelad M. Dawlaty et al.   DEVELOPMENTAL CELL

Paired Related Homeobox Protein 1 is a Regulator of Stemness in Adult Neural Stem/Progenitor Cells

(2013) K. Shimozaki et al.   JOURNAL OF NEUROSCIENCE

TET1 Controls CNS 5-Methylcytosine Hydroxylation, Active DNA Demethylation, Gene Transcription, and Memory Formation

(2013) Garrett A. Kaas et al.   NEURON

Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

(2013) Andrii Rudenko et al.   NEURON

Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion

(2012) Toshiaki Nakashiba et al.   CELL

Mcm10 Plays a Role in Functioning of the Eukaryotic Replicative DNA Helicase, Cdc45-Mcm-GINS

(2012) George Watase et al.   CURRENT BIOLOGY

Epigenetic regulation of stem cells differentiating along the neural lineage

(2012) Volkan Coskun et al.   CURRENT OPINION IN NEUROBIOLOGY

Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components

(2012) Mai Kanke et al.   EMBO JOURNAL

Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells

(2012) Hiroyoshi Kunimoto et al.   Scientific Reports

Neural stem cells: mechanisms and modeling

(2012) Jun Yao et al.   Protein & Cell

The Genetic and Epigenetic Journey of Embryonic Stem Cells into Mature Neural Cells

(2012) Brendan M. Olynik et al.   Frontiers in Genetics

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

(2011) Kelly Moran-Crusio et al.   CANCER CELL

TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation

(2011) Luisa Cimmino et al.   Cell Stem Cell

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells

(2011) H. Wu et al.   GENES & DEVELOPMENT

GalR2/3 mediates proliferative and trophic effects of galanin on postnatal hippocampal precursors

(2011) Christopher Abbosh et al.   JOURNAL OF NEUROCHEMISTRY

Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells

(2011) Yufei Xu et al.   MOLECULAR CELL

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

(2011) Kristine Williams et al.   NATURE

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells

(2011) Seiji Hitoshi et al.   NATURE NEUROSCIENCE

5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

(2011) Keith E Szulwach et al.   NATURE NEUROSCIENCE

Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity

(2011) Johannes M. Freudenberg et al.   NUCLEIC ACIDS RESEARCH

Quiescent and Active Hippocampal Neural Stem Cells with Distinct Morphologies Respond Selectively to Physiological and Pathological Stimuli and Aging

(2010) Sebastian Lugert et al.   Cell Stem Cell

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Committed Neuronal Precursors Confer Astrocytic Potential on Residual Neural Precursor Cells

(2009) Masakazu Namihira et al.   DEVELOPMENTAL CELL

Acquired mutations in TET2 are common in myelodysplastic syndromes

(2009) Saskia M C Langemeijer et al.   NATURE GENETICS

The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelination

(2009) K. Kucharova et al.   NEUROSCIENCE

Mutation inTET2in Myeloid Cancers

(2009) François Delhommeau et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

A role for adult TLX-positive neural stem cells in learning and behaviour

(2008) Chun-Li Zhang et al.   NATURE

Enumeration of Neural Stem and Progenitor Cells in the Neural Colony-Forming Cell Assay

(2008) Sharon A. Louis et al.   STEM CELLS