Quality control of chemically damaged RNA

The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

(2015) Bogdan I. Fedeles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Modification of miR-184 Enables It to Target Bcl-xL and Bcl-w

(2015) Jian-Xun Wang et al.   MOLECULAR CELL

O6-Methylguanosine leads to position-dependent effects on ribosome speed and fidelity

(2015) Benjamin H. Hudson et al.   RNA

Non-homologous functions of the AlkB homologs

(2015) Rune Ougland et al.   Journal of Molecular Cell Biology

Mechanism and Function of Oxidative Reversal of DNA and RNA Methylation

(2014) Li Shen et al.   Annual Review of Biochemistry

Regulatory mechanisms of RNA function: emerging roles of DNA repair enzymes

(2014) Laure Jobert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

An Active Role for the Ribosome in Determining the Fate of Oxidized mRNA

(2014) Carrie L. Simms et al.   Cell Reports

Roles of YB-1 under arsenite-induced stress: Translational activation of HSP70 mRNA and control of the number of stress granules

(2013) Toru Tanaka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Hbs1-Dom34 Protein Complex Functions in Non-stop mRNA Decay in Mammalian Cells

(2013) Syuhei Saito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleic acid oxidation: an early feature of Alzheimer's disease

(2013) Melissa A. Bradley-Whitman et al.   JOURNAL OF NEUROCHEMISTRY

Global analysis of RNA oxidation in Saccharomyces cerevisiae

(2012) Anastasia McKinlay et al.   BIOTECHNIQUES

RNA Degradation in Saccharomyces cerevisae

(2012) Roy Parker   GENETICS

The Human Base Excision Repair Enzyme SMUG1 Directly Interacts with DKC1 and Contributes to RNA Quality Control

(2012) Laure Jobert et al.   MOLECULAR CELL

Surveillance pathways rescuing eukaryotic ribosomes lost in translation

(2012) Marc Graille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NMD: a multifaceted response to premature translational termination

(2012) Stephanie Kervestin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Translation drives mRNA quality control

(2012) Christopher J Shoemaker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance

(2011) J Peter Svensson et al.   BMC Systems Biology

The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA

(2011) J. M. Whipple et al.   GENES & DEVELOPMENT

UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation

(2011) Henrik Sahlin Pettersen et al.   NUCLEIC ACIDS RESEARCH

Kinetic analysis reveals the ordered coupling of translation termination and ribosome recycling in yeast

(2011) C. J. Shoemaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

tRNAs Marked with CCACCA Are Targeted for Degradation

(2011) J. E. Wilusz et al.   SCIENCE

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly

(2010) Mohamed M. Emara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of ABCE1 in Eukaryotic Posttermination Ribosomal Recycling

(2010) Andrey V. Pisarev et al.   MOLECULAR CELL

Dom34:Hbs1 Promotes Subunit Dissociation and Peptidyl-tRNA Drop-Off to Initiate No-Go Decay

(2010) C. J. Shoemaker et al.   SCIENCE

Polynucleotide Phosphorylase ProtectsEscherichia coliagainst Oxidative Stress†

(2009) Jinhua Wu et al.   BIOCHEMISTRY

A role for ubiquitin in the clearance of nonfunctional rRNAs

(2009) K. Fujii et al.   GENES & DEVELOPMENT

The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress inSaccharomyces cerevisiae

(2009) Debrah M. Thompson et al.   JOURNAL OF CELL BIOLOGY

APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

(2009) C. Vascotto et al.   MOLECULAR AND CELLULAR BIOLOGY

A Convergence of rRNA and mRNA Quality Control Pathways Revealed by Mechanistic Analysis of Nonfunctional rRNA Decay

(2009) Sarah E. Cole et al.   MOLECULAR CELL

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

(2009) T. Barnes et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial iron accumulation with age and functional consequences

(2008) Arnold Y.  Seo et al.   AGING CELL

Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stress

(2008) Jinhua Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RNA under attack: Cellular handling of RNA damage

(2008) Elisabeth J. Wurtmann et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Rtt101 and Mms1 in budding yeast form a CUL4DDB1-like ubiquitin ligase that promotes replication through damaged DNA

(2008) Iram Waris Zaidi et al.   EMBO REPORTS

Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy

(2008) Tim Hofer et al.   EXPERIMENTAL GERONTOLOGY

Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1

(2008) I. Chernyakov et al.   GENES & DEVELOPMENT

Ammonia induces RNA oxidation in cultured astrocytes and brainin vivo

(2008) Boris Görg et al.   HEPATOLOGY

Depurination of Brome Mosaic Virus RNA3in VivoResults in Translation-dependent Accelerated Degradation of the Viral RNA

(2008) Rikesh Gandhi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Abasic Endonuclease Activity of Human Ape1 on Alternative Substrates, as Well as Effects of ATP and Sequence Context on AP Site Incision

(2008) Brian R. Berquist et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA

(2008) Cai-Guang Yang et al.   NATURE

Rex1p deficiency leads to accumulation of precursor initiator tRNAMet and polyadenylation of substrate RNAs in Saccharomyces cerevisiae

(2008) S. G. Ozanick et al.   NUCLEIC ACIDS RESEARCH

Viral AlkB proteins repair RNA damage by oxidative demethylation

(2008) Erwin van den Born et al.   NUCLEIC ACIDS RESEARCH

Messenger RNA Oxidation Occurs Early in Disease Pathogenesis and Promotes Motor Neuron Degeneration in ALS

(2008) Yueming Chang et al.   PLoS One

Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation

(2008) L. A. Copela et al.   RNA

tRNA cleavage is a conserved response to oxidative stress in eukaryotes

(2008) D. M. Thompson et al.   RNA