Article
Oncology
Yongguang Yang, Weihuang Chen, Haiqiang Cen, Zuobiao Li, Xiaoqing Di, Yongjun Wu, Lijuan Liu
Summary: This study retrospectively analyzed the clinical data of 10 patients with intrahepatic biliary cystadenoma (IBC) and aimed to improve the understanding and treatment of this rare benign cystic tumor of the liver. The study emphasized the importance of communication with pathologists, attention to cyst morphology and fluid properties during surgery, as well as the consideration of hepatectomy for suspicious cases to avoid reoperation.
FRONTIERS IN ONCOLOGY
(2022)
Article
Psychology, Multidisciplinary
Loredana Buonaccorso, Sara Alquati, Luca Ghirotto, Alice Annini, Silvia Tanzi
Summary: This study examines the use and training of dignity therapy among non-psychotherapist healthcare professionals, as well as the perception of palliative care professionals towards dignity therapy.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Critical Care Medicine
Steven M. Hollenberg, David R. Janz, May Hua, Mark Malesker, Nida Qadir, Bram Rochwerg, Curtis N. Sessler, Geneva Tatem, Todd W. Rice
Summary: This article outlines the experiences and lessons learned from clinicians during the COVID-19 pandemic, including practices that will be abandoned, new practices to be adopted, and proposed changes to the healthcare system.
Article
Pediatrics
John G. Frohna, Linda A. Waggoner-Fountain, Jill Edwards, Jill J. Fussell, Beth Wueste, Joseph Gigante, Robert J. Vinci, Nicholas M. Heitkamp, Mekala K. Neelakantan, Laura E. Degnon, Rebecca L. Blankenburg
Summary: The pediatric education community innovatively supported applicants and training programs during the pandemic by using virtual cafes and regional webinars, leading to a successful virtual recruitment process. Surveys indicated that virtual interviews were effective, saving time and money for both applicants and programs, with programs maintaining a high rate of filling positions.
Editorial Material
Engineering, Biomedical
James Sulzer, Lindsay S. Karfeld-Sulzer
Summary: The author, as a technologically-adept parent, shares a first-person perspective on the current state of pediatric neurorehabilitation after their daughter's severe traumatic brain injury. They discuss the challenges faced, technological approaches taken, and lessons learned during this period, providing insights for rehabilitation engineering researchers to consider when developing new technologies for pediatric rehabilitation.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Article
Chemistry, Multidisciplinary
Nuphar Veiga, Yael Diesendruck, Dan Peer
Summary: Designing a therapeutic modality with specific delivery to certain organs, tissues, or cell types is essential for efficient treatment and minimizing off-target side effects. Nanoparticles loaded with various drugs have emerged as a promising approach to achieve this goal. However, successful targeted delivery requires overcoming multiple biological barriers, such as systemic distribution, tissue penetration, and intracellular trafficking. Recent advances in understanding these barriers and functionalizing nanoparticles with targeting moieties have shown tremendous progress. Implementing new approaches like multi-functionalized nanocarriers and machine learning models can further enhance the design of safe and cell-specific nanoparticle delivery systems. This review critically examines the current progress in the field and proposes novel strategies to improve cell-specific delivery of therapeutic payloads.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Nutrition & Dietetics
Lorraine Brennan, Baukje de Roos
Summary: Omics technologies, including metabolomics, transcriptomics, proteomics, and metagenomics, are increasingly important in nutrition science, especially with regard to precision nutrition and individual responses to dietary interventions. Metabolomics plays a key role in developing biomarkers of food intake, while interdisciplinary collaborations are crucial for data analysis and interpretation.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Pharmacology & Pharmacy
Marina Mordenti, Manila Boarini, Fabio D'Alessandro, Elena Pedrini, Manuela Locatelli, Luca Sangiorgi
Summary: The use of disease registries as a source of real-world data for regulatory decision-making is discussed in this article. The study focuses on the remodeling of the Registry of Multiple Osteochondromas-REM, highlighting the key stages of the process and the three categories involved: semantic interoperability, data quality, and governance.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Medicine, Research & Experimental
Mengjie Kong, Kang Xie, Minghui Lv, Jufei Li, Jianyu Yao, Kaixuan Yan, Xiaoqin Wu, Ying Xu, Dewei Ye
Summary: Diabetes and its complications place a huge burden on global medical resources, with prevention of complications being a major challenge in diabetes management. Phytochemicals have immense potential in developing new therapeutic approaches, particularly in the realm of metabolic inflammation.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Energy & Fuels
Daniele Serra, Daniele Mardero, Luca Di Stefano, Samuele Grillo
Summary: This paper discusses the accessibility of electrical energy consumption data for low voltage end users in smart grids, drawing inspiration from Italy's regulatory and technological approach. It proposes a solution and a classification framework for post-metering value-added services, emphasizing the importance of certification, regulatory support for technological innovation, and customer-oriented solutions for a flourishing market.
Article
Oncology
Molly Li, Kevin Mok, Tony Mok
Summary: Patients with mutant EGFR-positive NSCLC benefit from TKI treatment. PF00299804, a second-generation EGFR TKI, has shown the potential to overcome the T790M mutation and improve treatment outcomes.
Article
Immunology
Steven B. Black, Rebecca E. Chandler, Kathryn M. Edwards, Miriam C. J. M. Sturkenboom
Summary: During the SARS-CoV-2 pandemic, questions about vaccine safety arose. This article reviews the various tools and capabilities used for monitoring vaccine safety, discusses their strengths and limitations, and highlights the challenges faced by middle and low income countries due to unequal vaccine safety pharmacovigilance capacity.
Editorial Material
Biochemistry & Molecular Biology
Ines Hassan, Genevie Fernandes, Mitsuru Mukaigawara, Devi Sridhar
Summary: Pandemic preparedness plans should prioritize fair access to diagnostics, vaccines, and therapeutics, and include strategies to build trust and combat disinformation.
Review
Energy & Fuels
Vandana Molahalli, K. Chaithrashree, Muskan Kumari Singh, Manica Agrawal, Syam G. Krishnan, Gurumurthy Hegde
Summary: Supercapacitors are gaining popularity in the field of energy storage devices due to their high power density, long cycle stability, and quick charge/discharge rates. This review focuses on contemporary methods to increase the power density, rate capability, cycle stability, and energy density of supercapacitors using hybrid topologies. The design of hybrid supercapacitor electrodes with high specific capacitance and the mechanisms involved are discussed, along with the evaluation of various electrode materials. The paper also summarizes the new trends and improvements in supercapacitor development.
JOURNAL OF ENERGY STORAGE
(2023)
Article
Nutrition & Dietetics
Irena Keser, Selma Cvijetic, Ana Ilic, Irena Colic Baric, Dario Boschiero, Jasminka Z. Ilich
Summary: The study found a high prevalence of osteosarcopenic adiposity syndrome (OSA) among nursing home residents, with most being overweight, high body fat, and low muscle and bone mass. Poor dietary intake was a common issue, with inadequate intake of protein, fiber, omega-3 fatty acids, and most micronutrients below recommendations.