Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy

Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles

(2016) E Fiacco et al.   CELL DEATH AND DIFFERENTIATION

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in themdxmouse

(2015) Caroline Godfrey et al.   HUMAN MOLECULAR GENETICS

Elusive sources of variability of dystrophin rescue by exon skipping

(2015) Maria Candida Vila et al.   Skeletal Muscle

Metabolic Dysfunction and Altered Mitochondrial Dynamics in the Utrophin-Dystrophin Deficient Mouse Model of Duchenne Muscular Dystrophy

(2015) Meghna Pant et al.   PLoS One

Enhanced Ca2+ influx from STIM1–Orai1 induces muscle pathology in mouse models of muscular dystrophy

(2014) Sanjeewa A. Goonasekera et al.   HUMAN MOLECULAR GENETICS

Dysferlin regulates cell membrane repair by facilitating injury-triggered acid sphingomyelinase secretion

(2014) A Defour et al.   Cell Death & Disease

Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair

(2014) Luana L. Scheffer et al.   Nature Communications

Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin

(2014) Mun Chan et al.   Skeletal Muscle

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

(2013) Christopher R. Heier et al.   EMBO Molecular Medicine

Dystrophin levels and clinical severity in Becker muscular dystrophy patients

(2013) J. C. van den Bergen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Identification of Disease Specific Pathways Usingin VivoSILAC Proteomics in Dystrophin DeficientmdxMouse

(2013) Sree Rayavarapu et al.   MOLECULAR & CELLULAR PROTEOMICS

Muscular dystrophy in dysferlin-deficient mouse models

(2013) Mark A. Hornsey et al.   NEUROMUSCULAR DISORDERS

Use of Quantitative Membrane Proteomics Identifies a Novel Role of Mitochondria in Healing Injured Muscles

(2012) Nimisha Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome proliferator-activated receptor γ coactivator 1-α gene transfer restores mitochondrial biomass and improves mitochondrial calcium handling in post-necroticmdxmouse skeletal muscle

(2012) Richard Godin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rescue of Dystrophic Skeletal Muscle by PGC-1α Involves a Fast to Slow Fiber Type Shift in the mdx Mouse

(2012) Joshua T. Selsby et al.   PLoS One

Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma

(2012) Vishnu Hosur et al.   Cancer Genetics

Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model

(2012) Vanessa E Jahnke et al.   Skeletal Muscle

Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

(2011) Christopher F Spurney et al.   BMC Cardiovascular Disorders

Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle

(2011) V. Ljubicic et al.   HUMAN MOLECULAR GENETICS

Dysferlin, Annexin A1, and Mitsugumin 53 Are Upregulated in Muscular Dystrophy and Localize to Longitudinal Tubules of the T-System With Stretch

(2011) Leigh B. Waddell et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Use of stable isotope labeling by amino acids in cell culture as a spike-in standard in quantitative proteomics

(2011) Tamar Geiger et al.   Nature Protocols

Dystrophin deficiency exacerbates skeletal muscle pathology in dysferlin-null mice

(2011) Renzhi Han et al.   Skeletal Muscle

Efficient recovery of dysferlin deficiency by dual adeno-associated vector-mediated gene transfer

(2010) William Lostal et al.   HUMAN MOLECULAR GENETICS

Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs

(2010) DeWayne Townsend et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-invasive Optical Imaging of Muscle Pathology in mdx Mice Using Cathepsin Caged Near-Infrared Imaging

(2010) Andreas R. Baudy et al.   MOLECULAR IMAGING AND BIOLOGY

Preclinical drug trials in themdxmouse: Assessment of reliable and sensitive outcome measures

(2009) Christopher F. Spurney et al.   MUSCLE & NERVE

Reciprocal amplification of ROS and Ca2+ signals in stressed mdx dystrophic skeletal muscle fibers

(2009) Vyacheslav M. Shkryl et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

(2009) Douglas P. Millay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx mice

(2008) Rainer Ng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanisms of Muscle Degeneration, Regeneration, and Repair in the Muscular Dystrophies

(2008) Gregory Q. Wallace et al.   Annual Review of Physiology

Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models

(2008) Yuko Iwata et al.   HUMAN MOLECULAR GENETICS