LH prevents cisplatin-induced apoptosis in oocytes and preserves female fertility in mouse

1*Long-term outcome results of the phase III PROMISE-GIM6 study evaluating the role of LHRH analog (LHRHa) during chemotherapy as a strategy to reduce ovarian failure in early breast cancer patients

(2015) M. Lambertini et al.   ANNALS OF ONCOLOGY

PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells

(2015) Arman Ghorbani et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Challenges and Potential for Ovarian Preservation with SERMs1

(2015) Alison Y. Ting et al.   BIOLOGY OF REPRODUCTION

New advances in ovarian autotransplantation to restore fertility in cancer patients

(2015) Mahmoud Salama et al.   CANCER AND METASTASIS REVIEWS

Goserelin for Ovarian Protection during Breast-Cancer Adjuvant Chemotherapy

(2015) Halle C.F. Moore et al.   NEW ENGLAND JOURNAL OF MEDICINE

Folliculogenesis Is Not Fully Inhibited during GnRH Analogues Treatment in Mice Challenging Their Efficiency to Preserve the Ovarian Reserve during Chemotherapy in This Model

(2015) Florence Horicks et al.   PLoS One

Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells

(2014) S Vandormael-Pournin et al.   CELL DEATH AND DIFFERENTIATION

Protective effects of sildenafil citrate administration on cisplatin-induced ovarian damage in rats

(2014) Mine Islimye Taskin et al.   GYNECOLOGICAL ENDOCRINOLOGY

Primary CNS Natural Killer/T-Cell Lymphoma of the Nasal Type Presenting in a Woman: Case Report and Review of the Literature

(2014) Hasmukh J. Prajapati et al.   JOURNAL OF CLINICAL ONCOLOGY

PKA-Mediated Phosphorylation of ATR Promotes Recruitment of XPA to UV-Induced DNA Damage

(2014) Stuart G. Jarrett et al.   MOLECULAR CELL

Role of AKT signaling in DNA repair and clinical response to cancer therapy

(2014) Q. Liu et al.   NEURO-ONCOLOGY

Targeted anti-apoptosis activity for ovarian protection against chemotherapy-induced ovarian gonadotoxicity

(2014) Shun-Jen Tan et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway

(2014) E. Bolcun-Filas et al.   SCIENCE

Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network

(2013) S-Y Kim et al.   CELL DEATH AND DIFFERENTIATION

Seeking the origin of female germline stem cells in the mammalian ovary

(2013) Massimo De Felici et al.   REPRODUCTION

p63 the guardian of human reproduction

(2012) Ivano Amelio et al.   CELL CYCLE

Isolated primate primordial follicles require a rigid physical environment to survive and grow in vitro

(2012) J.E. Hornick et al.   HUMAN REPRODUCTION

Regulatory role of kit ligand–c-kit interaction and oocyte factors in steroidogenesis by rat granulosa cells

(2012) Tomoko Miyoshi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

DNA Damage-Induced Primordial Follicle Oocyte Apoptosis and Loss of Fertility Require TAp63-Mediated Induction of Puma and Noxa

(2012) Jeffrey B. Kerr et al.   MOLECULAR CELL

Reply to: Cisplatin-induced primordial follicle oocyte killing and loss of fertility are not prevented by imatinib

(2012) Emiliano Maiani et al.   NATURE MEDICINE

LH and hCG Action on the Same Receptor Results in Quantitatively and Qualitatively Different Intracellular Signalling

(2012) Livio Casarini et al.   PLoS One

Estradiol Promotes and Maintains Cumulus Cell Expression of Natriuretic Peptide Receptor 2 (NPR2) and Meiotic Arrest in Mouse OocytesIn Vitro

(2011) Meijia Zhang et al.   ENDOCRINOLOGY

In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates

(2011) Mary B. Zelinski et al.   FERTILITY AND STERILITY

Pre-ovulatory LH/hCG surge decreases C-type natriuretic peptide secretion by ovarian granulosa cells to promote meiotic resumption of pre-ovulatory oocytes

(2011) K. Kawamura et al.   HUMAN REPRODUCTION

Detection of DNA damage in oocytes of small ovarian follicles following phosphoramide mustard exposures of cultured rodent ovaries in vitro

(2011) Stephanie K. Petrillo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Preserving fertility during cancer treatment

(2009) Teresa K Woodruff   NATURE MEDICINE

Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death

(2009) Stefania Gonfloni et al.   NATURE MEDICINE

Kit ligand promotes first polar body extrusion of mouse preovulatory oocytes

(2009) Yinghui Ye et al.   Reproductive Biology and Endocrinology

Luteinizing Hormone Signaling in Preovulatory Follicles Involves Early Activation of the Epidermal Growth Factor Receptor Pathway

(2008) Sara Panigone et al.   MOLECULAR ENDOCRINOLOGY