Review
Polymer Science
Caroline S. A. de Lima, Justine P. R. O. Varca, Victoria M. Alves, Kamila M. Nogueira, Cassia P. C. Cruz, M. Isabel Rial-Hermida, Slawomir S. Kadlubowski, Gustavo H. C. Varca, Ademar B. Lugao
Summary: Bladder cancer is the tenth most common type of cancer worldwide, predominantly affecting men. The current intravesical therapies for bladder cancer have limitations, leading researchers to develop drug delivery systems to improve treatment outcomes and patient experience.
Article
Chemistry, Physical
Jun Yang, Zhen Sun, Qingqing Dou, Shuhan Hui, Peng Zhang, Rui Liu, Di Wang, Shan Jiang
Summary: A multiplex NIR light-responsive hydrogel platform (SA/DOX@hydrogel) is created for controlled synergetic chemotherapy and photothermal cancer therapy. The platform incorporates Ag nanoparticles doped SnS2 nanoflowers (SA) for photothermal effect and doxorubicin (DOX) for chemotherapy. The heat generated by NIR irradiation induces the release of DOX, while SA converts NIR light into thermal energy. In vitro and in vivo studies demonstrate the high efficacy of the SA/DOX@hydrogel system in killing cancer cells and suppressing tumor growth, making it a promising approach for cancer treatment.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Materials Science, Ceramics
Zachary Kegley, Michael Makay, Joshua Rogers, Katrina Phelps, Colleen Malcom, David Hellmig, Anna Kroninger, Xiangdong Bi
Summary: The purpose of this research is to develop a hydrogel delivery system using PAMAM dendrimer to enhance the solubility and sustained release of hydrophobic drugs. The research shows that with the presence of PAMAM dendrimer, the solubility of diflunisal in water is significantly improved and the hydrogel system can achieve sustained release of the drug.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Medicinal
Zara Khizer, Muhammad R. R. Akram, Muhammad Azam Tahir, Weidong Liu, Shan Lou, Barbara R. R. Conway, Muhammad Usman Ghori
Summary: Overactive bladder (OAB) is a complex condition characterized by frequent urinary urgency, nocturia, and urinary incontinence. Gabapentin is an effective treatment for OAB, but its poor bioavailability due to narrow absorption window is a concern. In this study, an extended release, intragastric floating system was developed using 3D printing technology to improve gabapentin absorption and management of OAB.
Article
Materials Science, Multidisciplinary
Malvika Chawla, R. D. Kaushik, Mayank Kumar Malik, Vishakha Pundir, Jaspal Singh, Hafeezur Rehmaan
Summary: This study investigates the drug release dynamics and anti-inflammatory activity of the roflumilast analogue with dendrimer. The results show that the RofA-Dendrimer complex has high encapsulation potency and loading capability, and releases the drug progressively, making it suitable for sustained delivery. Drug release kinetics analysis indicates non-Fickian diffusion. Furthermore, the solubility of roflumilast increases with different dendrimer generations and pH levels.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Yuling He, Shuwen Guo, Yue Zhang, Ying Liu, Huangxian Ju
Summary: A biomimetic polymersome with sustained drug release through near-infrared (NIR) pre-activation is highlighted, offering highly efficient tumor therapeutic effect through combined sustained drug release and concurrent hypoxia intensification.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Materials Science, Biomaterials
Medha Surendranath, M. R. Rekha, Ramesh Parameswaran
Summary: This article discusses the importance of mucoadhesive drug delivery and innovations in drug transportation. It also highlights the crucial role of anatomical and physiological knowledge of mucosal tissue in research.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Engineering, Environmental
Huixin Wang, Wenshen Wang, Chengpan Li, Ao Xu, Bensheng Qiu, Fenfen Li, Weiping Ding
Summary: This study presented a novel microneedle system loaded with the multipurpose small molecule Flav7 for high-efficiency light-activated drug release for chemotherapy and high-performance light-controlled thermotherapy of tumors, as well as remarkable NIR-II fluorescence imaging to guide chemo-thermal therapy.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Biophysics
Limin Chang, Xiaojun Liu, Jingjing Zhu, Yuanxu Rao, Danyang Chen, Yong Wang, Youliang Zhao, Jianglei Qin
Summary: This study developed degradable hydrogels with thermo-response for localized anti-tumor therapy. The hydrogels showed good biocompatibility and biodegradability, reducing the toxicity of the drug through sustained release behavior. The anti-tumor effect was further enhanced by NIR-triggered drug release regulated by the photo-thermal property.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Medicine, Research & Experimental
Yanan Zhang, Xingang Yang, Shengnan Xu, Wenjia Jiang, Zhongwei Gu, Miao Guo, Jifu Wei
Summary: This study constructed dendritic peptide-based multifunctional nanoparticles (Au@SPP@DOX) for enhanced cancer therapy. The nanoparticles showed good biocompatibility and could accumulate at tumor sites to release the loaded DOX. Under low-dose radiation, Au@SPP@DOX induced reactive oxygen species production, mitochondrial dysfunction, and tumor cell apoptosis.
MOLECULAR PHARMACEUTICS
(2023)
Article
Chemistry, Multidisciplinary
E. Murugan, V. Yogaraj
Summary: In this study, poly (amidoamine) dendrimers (generation G2 and G3) were synthesized as drug carriers to enhance the solubility and sustained release of furosemide (FRSD). The dendrimers significantly increased the solubility and release time of FRSD compared with pure FRSD. Cytotoxicity studies indicated reduced toxicity and improved bioavailability of FRSD when delivered using these dendrimer-based drug carriers. The results suggest that the dendrimer-based drug carriers are promising for poorly soluble drugs and could be used for real-time drug delivery applications.
FRONTIERS IN CHEMISTRY
(2023)
Article
Chemistry, Applied
Araceli Martin-Illana, Eva Chinarro, Raul Cazorla-Luna, Fernando Notario-Perez, M. D. Veiga-Ochoa, Juan Rubio, Aitana Tamayo
Summary: Karaya gum, pectin, and xanthan gum were tested as candidates for manufacturing mucoadhesive trilayer films for vaginal administration of the antiviral Tenofovir (TFV). The swelling profile of the films was determined by impedance spectroscopy, and it was found that fast water penetration facilitated the formation of polyelectrolyte complexes (PEC) and controlled release. The incorporation of an inorganic drug release regulator weakened the polymeric chains, enhancing the ionic mobility and forming low molecular weight PECs in films made with karaya gum. Pectin-based films were not suitable for pharmaceutical formulation due to their different mechanical properties. However, mucoadhesive trilayer films produced with xanthan gum showed moderate swelling, improved wettability, and a controlled release of TFV.
CARBOHYDRATE POLYMERS
(2022)
Article
Pharmacology & Pharmacy
Ekapol Limpongsa, Peera Tabboon, Sarunya Tuntiyasawasdikul, Bungorn Sripanidkulchai, Thaned Pongjanyakul, Napaphak Jaipakdee
Summary: This study aimed to develop and comprehensively evaluate a mucoadhesive vaginal gel for the sustained release of DAs. Different mucoadhesive polymers as gelling agents were investigated, and it was found that PCP:HPMC-based gels exhibited higher mucoadhesion and sustained release properties. These gels could be a proper delivery system for vaginal administration of DAs.
Article
Materials Science, Biomaterials
Ellen Ngarande, Emma Doubell, Ousman Tamgue, Manuel Mano, Paul Human, Mauro Giacca, Neil Hamer Davies
Summary: This study investigates the use of a modified fibrin hydrogel combined with Invivofectamine((R)) 3.0 as a delivery system for small interfering RNA (siRNA). PEGylation of the fibrin hydrogel allows for controlled release of siRNA-lipopolyplexes and improves the stability of fibrin. In vitro and in vivo experiments demonstrate that the combination of the lipid nonviral transfection vector and fibrin enhances siRNA transfection efficacy and muscle growth in mice.
REGENERATIVE BIOMATERIALS
(2023)
Article
Cell & Tissue Engineering
Fengyi Liu, Xu Wang, Yuzhou Li, Mingxing Ren, Ping He, Lu Wang, Jie Xu, Sheng Yang, Ping Ji
Summary: In this study, a photocrosslinked GelMA/PAMAM-MA hydrogel was developed as a stem cell carrier for cartilage repair. The hybrid hydrogel showed improved structural and mechanical properties compared to GelMA alone, and demonstrated a sufficient ability to promote cartilage regeneration in both in vitro and in vivo experiments. This study provides new insight into the design strategy of stem cell delivery scaffolds.
STEM CELL RESEARCH & THERAPY
(2022)
Review
Materials Science, Biomaterials
Yonghe Zhang, Beilei Wang, Ruibo Zhao, Quan Zhang, Xiangdong Kong
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2020)
Article
Engineering, Biomedical
Lingying Wu, Yuling Wu, Xun Che, Dandan Luo, Jiaju Lu, Ruibo Zhao, Muhammed Zubair Iqbal, Quan Zhang, Xiumei Wang, Xiangdong Kong
Summary: This study recruited chitosan for selenium nanoparticles synthesis and developed a thermoresponsive nanocomposite hydrogel with the addition of glycerol phosphate. Incorporation of SeNPs in the hydrogel was found to improve its mechanical properties and antioxidant activity. The combination of these two technologies could be a promising antioxidant system for drug delivery and tissue engineering.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2021)
Article
Engineering, Biomedical
Yonghe Zhang, Ruibo Zhao, Jia Liu, Hao Kong, Kebiao Zhang, Yuan-Ning Zhang, Xiangdong Kong, Quan Zhang, Yanli Zhao
Summary: The development of boron dipyrromethene (BDP)-based nanoparticles for activatable photodynamic therapy (PDT) shows promising results in achieving tumor penetration and specific recognition by cancer cells, while also allowing for efficient disassembly into single PS molecules for effective PDT under acidic conditions.
Article
Engineering, Biomedical
Bowen Chen, Jie Cao, Kebiao Zhang, Yuan-Ning Zhang, Jiaju Lu, Muhammad Zubair Iqbal, Quan Zhang, Xiangdong Kong
Summary: A BODIPY-HA NPs was prepared for combined cancer PDT and PTT, which exhibited better anticancer effect than PTT alone, suggesting a promising nanomedicine for synergistic cancer therapy.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2021)
Article
Pharmacology & Pharmacy
Dandan Luo, Xiaochun Xu, M. Zubair Iqbal, Qingwei Zhao, Ruibo Zhao, Jabeen Farheen, Quan Zhang, Peiliang Zhang, Xiangdong Kong
Summary: A novel nanoparticle HAp-PEI/siKras was successfully fabricated for efficient targeted delivery of siRNA to pancreatic cancer cells, achieving successful gene silencing and tumor-targeted therapy. Experimental results confirmed its effectiveness in inhibiting pancreatic cancer cell proliferation in vitro, while exhibiting no cytotoxicity towards normal pancreatic cells.
Article
Biophysics
Yuan-Ning Zhang, Ruibo Zhao, Jie Cao, Bowen Chen, Dandan Luo, Jiaju Lu, Muhammed Zubair Iqbal, Quan Zhang, Xiangdong Kong
Summary: The study demonstrates that heptamannosylated beta-cyclodextrin derivatives can induce M2 macrophage polarization and promote wound healing, showing potential therapeutic effects in inhibiting inflammation.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Materials Science, Biomaterials
Yuxin Wang, Daliang Zhong, Fan Xie, Siying Chen, Zaiqiang Ma, Xinyan Yang, M. Zubair Iqbal, Quan Zhang, Jiaju Lu, Shibo Wang, Ruibo Zhao, Xiangdong Kong
Summary: In this study, a one-step method for the preparation of manganese phosphate-doxorubicin nanomedicines was proposed by manganese ion and doxorubicin complexation. The nanocomplexes exhibited controlled sizes and shapes, and the drug molecules were integrated into the nanocarriers by mimetic mineralization, allowing for high-efficiency drug release and achieving significant cancer inhibition.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2022)
Article
Nanoscience & Nanotechnology
Jie Cao, Yonghe Zhang, Wenjun Shi, Lehan Du, Zhihua Cui, Shujie Liu, Ruibo Zhao, Shibo Wang, Quan Zhang, Xiangdong Kong
Summary: The development and use of mitochondria-targeted photosensitizers hold great promise for enhancing the efficacy of photodynamic therapy. This study synthesized boron dipyrromethene (BODIPY) photosensitizers conjugated with pyridine cations and encapsulated them with liposomal nanoparticles for increased stability. The results showed that one of the photosensitizers had the highest efficiency for targeted delivery to mitochondria and effectively inhibited tumor growth.
ACS APPLIED NANO MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Liang Luan, Lehan Du, Wenjun Shi, Yunhui Li, Quan Zhang
Summary: In this study, a ligand containing benzoselenadiazole was designed and synthesized to construct a benzoselenadiazole-doped metal-organic framework (Se-MOF). The Se-MOF exhibited regular crystallinity and high porosity and effectively killed bacteria and inhibited the formation of bacterial biofilms under visible-light irradiation.
Article
Pharmacology & Pharmacy
Lehan Du, Wenjun Shi, Xin Hao, Liang Luan, Shibo Wang, Jiaju Lu, Quan Zhang
Summary: Photosensitive metal-organic framework (MOF) nanoparticles were developed to enhance the penetration of antibiotics into bacterial biofilms, achieving the eradication of biofilms through synergistic photodynamic and antibiotic therapy.
Article
Materials Science, Biomaterials
Zhe Tang, Israt Ali, Yike Hou, Ozioma Udochukwu Akakuru, Quan Zhang, Asim Mushtaq, Han Zhang, Yuguang Lu, Xuehua Ma, Jian Ge, M. Zubair Iqbal, Xiangdong Kong
Summary: In this study, a nanotheranostic agent based on plasmonic nanostructures was developed for tumor-targeted NIR-II photothermal-augmented nanocatalytic therapy. The agent exhibited excellent targeting ability and photothermal conversion efficiency, as well as peroxidase and catalase activities for catalytic therapy and relieving tumor hypoxia. In vivo experiments demonstrated remarkable therapeutic effects of the agent on tumors.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Materials Science, Biomaterials
Daliang Zhong, Yuxin Wang, Fan Xie, Siying Chen, Xinyan Yang, Zaiqiang Ma, Shibo Wang, M. Zubair Iqbal, Jian Ge, Quan Zhang, Ruibo Zhao, Xiangdong Kong
Summary: Photothermal therapy using Prussian blue (PB) as a reagent has promising potential for cancer treatment. However, the low conversion efficiency and stability of PB hinder its translational potential. By integrating PB with calcium phosphate (CaP) through biomineralization, the photothermal performance and stability of PB can be significantly improved.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Review
Materials Science, Biomaterials
Ruibo Zhao, Jinping Cao, Xinyan Yang, Quan Zhang, Muhammad Zubair Iqbal, Jiaju Lu, Xiangdong Kong
Summary: Macrophages with M1 phenotype show promise for cancer therapy, but their transformation into M2 type in tumour microenvironment can hinder treatment. Advances in inorganic nanomaterials have facilitated macrophage regulation-based cancer treatments. This approach offers a flexible and novel method for immune materials in cancer therapy.
BIOMATERIALS SCIENCE
(2021)
Article
Materials Science, Biomaterials
Hao Kong, Ruibo Zhao, Quan Zhang, Muhammed Zubair Iqbal, Jiaju Lu, Qingwei Zhao, Dandan Luo, Cui Feng, Kangjian Zhang, Xinyuan Liu, Xiangdong Kong
BIOMATERIALS SCIENCE
(2020)
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)