RNA-binding protein QKI-5 inhibits the proliferation of clear cell renal cell carcinoma via post-transcriptional stabilization of RASA1 mRNA

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

(2016) Pratiti Bandopadhayay et al.   NATURE GENETICS

Emerging functions of the Quaking RNA-binding proteins and link to human diseases

(2016) Lama Darbelli et al.   Wiley Interdisciplinary Reviews-RNA

miR-134 Functions as a Tumor Suppressor in Cell Proliferation and Epithelial-to-Mesenchymal Transition by Targeting KRAS in Renal Cell Carcinoma Cells

(2015) Yiyang Liu et al.   DNA AND CELL BIOLOGY

International Variations and Trends in Renal Cell Carcinoma Incidence and Mortality

(2015) Ariana Znaor et al.   EUROPEAN UROLOGY

QKI-5 suppresses cyclin D1 expression and proliferation of oral squamous cell carcinoma cells via MAPK signalling pathway

(2015) X. Fu et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Therapeutic effects and associated adverse events of first-line treatments of advanced renal cell carcinoma (RCC): a meta-analysis

(2015) Lei Wang et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

RASSF6promotes p21Cip1/Waf1-dependent cell cycle arrest and apoptosis through activation of the JNK/SAPK pathway in clear cell renal cell carcinoma

(2014) Ying-Ying Liang et al.   CELL CYCLE

The role of HIF1α in renal cell carcinoma tumorigenesis

(2014) Lorraine J. Gudas et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

MicroRNAs 206 and 21 Cooperate To Promote RAS-Extracellular Signal-Regulated Kinase Signaling by Suppressing the Translation of RASA1 and SPRED1

(2014) S. B. Sharma et al.   MOLECULAR AND CELLULAR BIOLOGY

p120RasGAP Is a Mediator of Rho Pathway Activation and Tumorigenicity in the DLD1 Colorectal Cancer Cell Line

(2014) Shawna L. Organ et al.   PLoS One

The RNA-Binding Protein QKI Suppresses Cancer-Associated Aberrant Splicing

(2014) Feng-Yang Zong et al.   PLoS Genetics

The tumor suppressing effects of QKI-5 in prostate cancer

(2013) Yi Zhao et al.   CANCER BIOLOGY & THERAPY

The RasGAP Gene, RASAL2, Is a Tumor and Metastasis Suppressor

(2013) Sara Koenig McLaughlin et al.   CANCER CELL

Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites

(2013) M. Teplova et al.   GENES & DEVELOPMENT

MicroRNA-31 Activates the RAS Pathway and Functions as an Oncogenic MicroRNA in Human Colorectal Cancer by Repressing RAS p21 GTPase Activating Protein 1 (RASA1)

(2013) Defang Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

Hijacking the vasculature in ccRCC—co-option, remodelling and angiogenesis

(2013) Chao-Nan Qian   Nature Reviews Urology

Downregulation of tumor suppressor QKI in gastric cancer and its implication in cancer prognosis

(2012) Yongqian Bian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

As an independent unfavorable prognostic factor, IL-8 promotes metastasis of nasopharyngeal carcinoma through induction of epithelial–mesenchymal transition and activation of AKT signaling

(2012) Xin-Jian Li et al.   CARCINOGENESIS

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

(2012) A.-J. Chen et al.   GENES & DEVELOPMENT

Oncological outcome of surgical treatment in 336 patients with renal cell carcinoma

(2012) Zhi-Ling Zhang et al.   Chinese Journal of Cancer

E2F1 and RNA binding protein QKI comprise a negative feedback in the cell cycle regulation

(2011) Guodong Yang et al.   CELL CYCLE

Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration

(2011) Anja Mai et al.   JOURNAL OF CELL BIOLOGY

QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation

(2011) L. Novikov et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

The Quaking family of RNA-binding proteins: Coordinators of the cell cycle and differentiation

(2010) Bjoern Biedermann et al.   CELL CYCLE

Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer

(2010) Diego F. Calvisi et al.   JOURNAL OF HEPATOLOGY

MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis

(2010) Sudarshan Anand et al.   NATURE MEDICINE

The genetic basis of kidney cancer: a metabolic disease

(2010) W. Marston Linehan et al.   Nature Reviews Urology

RNA-Binding Protein Quaking, a Critical Regulator of Colon Epithelial Differentiation and a Suppressor of Colon Cancer

(2009) Guodong Yang et al.   GASTROENTEROLOGY

p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities

(2009) X-Y Yang et al.   ONCOGENE

Inhibition of MAPK Kinase Signaling Pathways Suppressed Renal Cell Carcinoma Growth and Angiogenesis In vivo

(2008) D. Huang et al.   CANCER RESEARCH

Decreased Expression of the RAS-GTPase Activating Protein RASAL1 Is Associated With Colorectal Tumor Progression

(2008) Miki Ohta et al.   GASTROENTEROLOGY

New implications for the QUAKING RNA binding protein in human disease

(2007) Carol Anne Chénard et al.   JOURNAL OF NEUROSCIENCE RESEARCH