Novel protective mechanism of reducing renal cell damage in diabetes: Activation AMPK by AICAR increased NRF2/OGG1 proteins and reduced oxidative DNA damage

Potential role for Nrf2 activation in the therapeutic effect of MG132 on diabetic nephropathy in OVE26 diabetic mice

(2012) Wenpeng Cui et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Tuberin Inhibits Production of the Matrix Protein Fibronectin in Diabetes

(2012) S. L. Habib et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Metformin opposes impaired AMPK and SIRT1 function and deleterious changes in core clock protein expression in white adipose tissue of genetically-obese db/db mice

(2011) P. W. Caton et al.   DIABETES OBESITY & METABOLISM

Novel mechanism of regulation of the DNA repair enzyme OGG1 in tuberin-deficient cells

(2010) S. L. Habib et al.   CARCINOGENESIS

Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo

(2010) Y. Dong et al.   DIABETES

Novel mechanism of reducing tumourigenesis: Upregulation of the DNA repair enzyme OGG1 by rapamycin-mediated AMPK activation and mTOR inhibition

(2010) Samy L. Habib et al.   EUROPEAN JOURNAL OF CANCER

Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb

(2009) M. N. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling

(2009) L.-A. Julien et al.   MOLECULAR AND CELLULAR BIOLOGY

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

(2009) D. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Oxidative DNA Damage in Diabetes: Tuberin Inactivation and Downregulation of DNA Repair Enzyme 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine-DNA Glycosylase

(2008) S. Simone et al.   DIABETES

Can patients with type 2 diabetes be treated with 5′-AMP-activated protein kinase activators?

(2008) W. W. Winder   DIABETOLOGIA

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

(2008) H. Boon et al.   DIABETOLOGIA

Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors

(2008) Samy L Habib et al.   Molecular Cancer