MYC interaction with the tumor suppressive SWI/SNF complex member INI1 regulates transcription and cellular transformation

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BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors

(2015) Dharmendra Dingar et al.   Journal of Proteomics

The spliceosome is a therapeutic vulnerability in MYC-driven cancer

(2015) Tiffany Y.-T. Hsu et al.   NATURE

MYC and metabolism on the path to cancer

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SWI/SNF chromatin remodeling complexes and cancer

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Residual Complexes Containing SMARCA2 (BRM) Underlie the Oncogenic Drive of SMARCA4 (BRG1) Mutation

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MYC Cofactors: Molecular Switches Controlling Diverse Biological Outcomes

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The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells

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MYC Phosphorylation at Novel Regulatory Regions Suppresses Transforming Activity

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Interplay between the Cancer Genome and Epigenome

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Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

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Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy

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Cancer Genetics and Epigenetics: Two Sides of the Same Coin?

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The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer

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Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding

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BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

Diverse Roles and Interactions of the SWI/SNF Chromatin Remodeling Complex Revealed Using Global Approaches

(2011) Ghia M. Euskirchen et al.   PLoS Genetics

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Reexpression of hSNF5 in Malignant Rhabdoid Tumor Cell Lines Causes Cell Cycle Arrest through a p21CIP1/WAF1-Dependent Mechanism

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The role of INI1/hSNF5 in gene regulation and cancerThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

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NAViGaTOR: Network Analysis, Visualization and Graphing Toronto

(2009) Kevin R. Brown et al.   BIOINFORMATICS

Genomic Analysis Using High-Density Single Nucleotide Polymorphism-Based Oligonucleotide Arrays and Multiplex Ligation-Dependent Probe Amplification Provides a Comprehensive Analysis of INI1/SMARCB1 in Malignant Rhabdoid Tumors

(2009) E. M. Jackson et al.   CLINICAL CANCER RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

BRG1 directly regulates nucleosome structure and chromatin looping of the α globin locus to activate transcription

(2009) Shin-Il Kim et al.   NUCLEIC ACIDS RESEARCH

BRG1 requirement for long-range interaction of a locus control region with a downstream promoter

(2009) S.-I. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modelling Myc inhibition as a cancer therapy

(2008) Laura Soucek et al.   NATURE

The chromatin-remodeling enzyme BRG1 coordinates CIITA induction through many interdependent distal enhancers

(2008) Zuyao Ni et al.   NATURE IMMUNOLOGY

Molecular basis of Pirh2-mediated p53 ubiquitylation

(2008) Yi Sheng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Optimization of experimental design parameters for high-throughput chromatin immunoprecipitation studies

(2008) Romina Ponzielli et al.   NUCLEIC ACIDS RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH