Article
Medicine, General & Internal
Giulia Brindisi, Valentina De Vittori, Rosalba De Nola, Elia Pignataro, Caterina Anania, Giovanna De Castro, Bianca Cinicola, Alessandra Gori, Ettore Cicinelli, Anna Maria Zicari
Summary: During the COVID-19 lockdown, there was an improvement in symptoms and a decrease in medication use among pediatric patients with asthma and allergic rhinitis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Immunology
Srijit Ghosh, Srijita Das, Rupsa Mondal, Salik Abdullah, Shirin Sultana, Sukhbir Singh, Aayush Sehgal, Tapan Behl
Summary: This review focuses on the impact of COVID-19 on type-2 asthmatic patients, with conflicting results suggesting that COVID-19 may worsen asthma attacks in severe cases, while an elevation of T-cells in type-2 asthmatic patients could reduce the severity of COVID-19. Future strategies should aim to better understand the exacerbation of asthma and its relationship to COVID-19.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Immunology
Dmitry Kudlay, Ilya Kofiadi, Musa Khaitov
Summary: Understanding the immune response to SARS-CoV-2, especially the T cell response, is crucial for vaccine development and disease control strategies. This review summarizes studies on the immune response to coronavirus infections, provides insights into T cell components, and presents the most informative methods for assessing the immune response to SARS-CoV-2 infection.
Article
Biochemical Research Methods
Rosanna W. Peeling, Samuel K. Sia
Summary: Throughout the COVID-19 pandemic, the role of testing has been critical and expanding. However, there are still gaps in developing tests to fit public health needs and providing equitable access. This article reviews the evolution of testing use cases during the pandemic and highlights challenges faced by test developers at each phase. Lessons learned and future cooperative efforts among stakeholders are summarized, including the development of new funding models, investment in adaptable open-platform technologies, building data connectivity infrastructures, and facilitating the translation of innovation into use.
Review
Endocrinology & Metabolism
Salvatore Corrao, Karen Pinelli, Martina Vacca, Massimo Raspanti, Christiano Argano
Summary: This review discusses the prevalence, pathophysiological mechanisms, and outcomes of COVID-19 infection in people with diabetes, proposing a rationale for using drugs prescribed in patients with diabetes and providing pragmatic clinical recommendations for dealing with COVID-19 in this patient population.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Immunology
Antonio Arenas, Carmen Borge, Alfonso Carbonero, Ignacio Garcia-Bocanegra, David Cano-Terriza, Javier Caballero, Antonio Arenas-Montes
Summary: After a year of the SARS-CoV-2 epidemic, there is still no specific effective treatment, so finding pharmacological and immunological mechanisms to control the infection is important. Using cow's milk immune to BCoV as a possible control measure against COVID-19, due to the close phylogenetic relationship between COVID-19 and BCoV viruses, can help with specific immune response.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Virology
Prabuddha S. Pathinayake, Nikhil T. Awatade, Peter A. B. Wark
Summary: Patients with chronic type 2 inflammatory lung diseases are less susceptible to SARS-CoV-2 infection. Recent research shows that type 2 cytokines, particularly IL-13, can reduce the risk of SARS-CoV-2 infection by altering the expression of ACE2 and TMPRSS2 receptors in the airway epithelium. This immune response also enhances mucin and glycocalyx secretion to restrict viral attachment.
Article
Oncology
Laura Mansi, Laurie Spehner, Etienne Daguindau, Kevin Bouiller, Hamadi Almotlak, Ulrich Stein, Adeline Bouard, Stefano Kim, Elodie Klajer, Marine Jary, Guillaume Meynard, Angelique Vienot, Charlee Nardin, Fernando Bazan, Quentin Lepiller, Virginie Westeel, Olivier Adotevi, Christophe Borg, Marie Kroemer
Summary: Cancer patients exposed to SARS-CoV-2 produced a high rate of specific antibodies, but lacked T-cell responses against the virus, indicating a deficiency in protective T-cell immunity. However, their immune memory against common viruses remained intact.
EUROPEAN JOURNAL OF CANCER
(2021)
Review
Virology
Bariaa A. Khalil, Sarra B. Shakartalla, Swati Goel, Bushra Madkhana, Rabih Halwani, Azzam A. Maghazachi, Habiba AlSafar, Basem Al-Omari, Mohammad T. Al Bataineh
Summary: This review examines the role of cytokines and chemokines in SARS-CoV-2 and its predecessors, highlighting the elevated levels of inflammatory mediators associated with disease severity. It also discusses potential treatment strategies targeting these factors.
Review
Medicine, General & Internal
Dan H. Barouch
Summary: This article reviews the protective effects of vaccination and prior infection on severe Covid-19, and proposes future research directions.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Biochemical Research Methods
Mohammad Ali Moni, Julian M. W. Quinn, Nese Sinmaz, Matthew A. Summers
Summary: The study identified key gene expression pathways altered with infection of the novel coronavirus SARS-CoV-2 through comparative genomic and transcriptomic analysis, including comparisons with SARS-CoV and MERS-CoV, as well as influenza A strains. Validation of SARS-CoV-2 infection response genes as disease-associated and identification of signaling pathway concordance between lung cell and blood cell infection responses were also highlighted in the research.
BRIEFINGS IN BIOINFORMATICS
(2021)
Review
Biochemistry & Molecular Biology
Haneen Imad Abufares, Leen Oyoun Alsoud, Mohammad A. Y. Alqudah, Mohd Shara, Nelson C. Soares, Karem H. Alzoubi, Waseem El-Huneidi, Yasser Bustanji, Sameh S. M. Soliman, Mohammad H. Semreen
Summary: The COVID-19 pandemic has caused global crises, and the development of vaccines has become a collaborative effort worldwide. WHO-approved vaccines have been shown to be safe and effective, enhancing immune response and reducing the risk of infection. However, the type of vaccine and individual health status have significant impacts on immune responses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Qin Liu, Qi Su, Fen Zhang, Hein M. Tun, Joyce Wing Yan Mak, Grace Chung-Yan Lui, Susanna So Shan Ng, Jessica Y. L. Ching, Amy Li, Wenqi Lu, Chenyu Liu, Chun Pan Cheung, David S. C. Hui, Paul K. S. Chan, Francis Ka Leung Chan, Siew C. Ng
Summary: By integrating clinical features and multi-omics data, the authors identified specific gut microbiome patterns associated with disease severity and development of post-acute COVID-19 syndrome. These findings highlight the potential utility of host phenotype and multi-kingdom microbiota profiling as a prognostic tool for patients with COVID-19.
NATURE COMMUNICATIONS
(2022)
Editorial Material
Immunology
Rustom Antia, M. Elizabeth Halloran
Summary: The article discusses the basic concepts underlying the transition from an epidemic to an endemic state, as well as the implications of this transition for COVID-19.
Article
Medicine, General & Internal
Umer Syed, Anuradhaa Subramanian, David C. Wraith, Janet M. Lord, Kirsty McGee, Krishna Ghokale, Krishnarajah Nirantharakumar, Shamil Haroon
Summary: This study found an association between SARS-CoV-2 infection and an increased incidence of IMIDs such as T1DM, IBD, and psoriasis. However, these findings may be influenced by ascertainment bias, and further research is needed to replicate and investigate these results in other populations.
Article
Medicine, Research & Experimental
Jianqing Gu, Shuang Liu, Yuxiang Zhi
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2019)
Article
Allergy
S. Liu, X. Wang, Yingyang Xu, Qun Xu, Yuxiang Zhi
ALLERGY AND ASTHMA PROCEEDINGS
(2019)
Article
Genetics & Heredity
Shuang Liu, Xue Wang, Yingyang Xu, Qun Xu, Yuxiang Zhi
ORPHANET JOURNAL OF RARE DISEASES
(2019)
Letter
Medicine, General & Internal
Shuang Liu, Yan You, Dan Chen, Jia-Ming Qian, Ji Li
CHINESE MEDICAL JOURNAL
(2019)
Review
Allergy
Yingyang Xu, Shuang Liu, Yan Zhang, Yuxiang Zhi
WORLD ALLERGY ORGANIZATION JOURNAL
(2020)
Article
Genetics & Heredity
Yang Cao, Shuang Liu, Yuxiang Zhi
ORPHANET JOURNAL OF RARE DISEASES
(2020)
Review
Allergy
Shuang Liu, Yang Cao, Tian Du, Yuxiang Zhi
Summary: The prevalence of asthma among COVID-19 patients varies widely across different countries or regions. However, asthma does not increase the risk of severe illness or poor prognosis in COVID-19 patients, and those with asthma have a lower risk of death compared to patients without asthma.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2021)
Article
Dermatology
Shuang Liu, Qun Xu, Yingyang Xu, Xue Wang, Yuxiang Zhi
EUROPEAN JOURNAL OF DERMATOLOGY
(2020)
Review
Dermatology
Shuang Liu, Yingyang Xu, Yaping Liu, Yuxiang Zhi
EUROPEAN JOURNAL OF DERMATOLOGY
(2019)
Article
Gastroenterology & Hepatology
Shuang Liu, Yan You, Gechong Ruan, Liangrui Zhou, Dan Chen, Dong Wu, Xuemin Yan, Shengyu Zhang, Weixun Zhou, Ji Li, Jiaming Qian
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY
(2020)
Letter
Medicine, General & Internal
Jian-Qing Gu, Shuang Liu, Yu-Xiang Zhi
CHINESE MEDICAL JOURNAL
(2018)
