Effect and Safety of Hydroxysafflor Yellow A for Injection in Patients with Acute Ischemic Stroke of Blood Stasis Syndrome: A Phase II, Multicenter, Randomized, Double-Blind, Multiple-Dose, Active-Controlled Clinical Trial

Study of serious adverse drug reactions using FDA-approved drug labeling and MedDRA

(2019) Leihong Wu et al.   BMC BIOINFORMATICS

Hydroxysafflor yellow A (HSYA) alleviates apoptosis and autophagy of neural stem cells induced by heat stress via p38 MAPK/MK2/Hsp27-78 signaling pathway

(2019) Hongbo Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Hydroxysafflor yellow A actives BKCa channels and inhibits L-type Ca channels to induce vascular relaxation

(2019) Na Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Herbal Medicine in Ischemic Stroke: Challenges and Prospective

(2018) Bhakta Prasad Gaire   Chinese Journal of Integrative Medicine

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

(2018) William J. Powers et al.   STROKE

Pharmacokinetic profiles of hydroxysafflor yellow A following intravenous administration of its pure preparations in healthy Chinese volunteers

(2015) Chang-Yin Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Scutellarin and caffeic acid ester fraction, active components of Dengzhanxixin injection, upregulate neurotrophins synthesis and release in hypoxia/reoxygenation rat astrocytes

(2013) Lijuan Chai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Endovascular Treatment for Acute Ischemic Stroke

(2013) Alfonso Ciccone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neuroprotection of hydroxysafflor yellow A in the transient focal ischemia: Inhibition of protein oxidation/nitration, 12/15-lipoxygenase and blood–brain barrier disruption

(2012) Li Sun et al.   BRAIN RESEARCH

Pathophysiologic Cascades in Ischemic Stroke

(2012) Changhong Xing et al.   International Journal of Stroke

Barthel Index for Stroke Trials

(2011) Terence J. Quinn et al.   STROKE

Pharmacokinetic comparisons of hydroxysafflower yellow A in normal and blood stasis syndrome rats

(2010) Yun Tian et al.   JOURNAL OF ETHNOPHARMACOLOGY

Exploring the Reliability of the Modified Rankin Scale

(2009) Terence J. Quinn et al.   STROKE

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE