期刊
CELL AND TISSUE RESEARCH
卷 367, 期 1, 页码 73-81出版社
SPRINGER
DOI: 10.1007/s00441-016-2492-9
关键词
Mitochondria; Targeting signals; Presequence proteases; Quality control; Peptide turnover
类别
资金
- DFG (Deutsche Forschungsgemeinschaft)
Mitochondria play a key role in several metabolic and cell biological pathways and have attracted increasing attention due to their implication in life-span, ageing and human diseases. Mitochondrial proteases have a special role in these multiple biological functions, as they are involved in the regulation of various processes, e.g., mitochondrial protein biogenesis and quality control, mitochondrial dynamics, mitophagy and programmed cell death. The mitochondrial presequence processing machinery serves the particular purpose of maturing the majority of incoming precursor proteins by presequence cleavage, to ensure a stable mature protein by trimming of intermediate N-termini and to remove free toxic targeting peptides.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据