Alteration of the late endocytic pathway in Charcot–Marie–Tooth type 2B disease

Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B

(2018) David Colecchia et al.   Autophagy

Post-Translational Modification and Subcellular Distribution of Rac1: An Update

(2018) Abdalla Abdrabou et al.   Cells

β1 integrin–dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin

(2017) Hiba Sabra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix Metalloproteinases: A challenging paradigm of cancer management

(2017) Ali Alaseem et al.   SEMINARS IN CANCER BIOLOGY

Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies

(2017) Mansour Haidar et al.   Frontiers in Molecular Neuroscience

Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways

(2017) et al.   Cancers

Regional Selectivity of rab5 and rab7 Protein Upregulation in Mild Cognitive Impairment and Alzheimer's Disease

(2017) Stephen D. Ginsberg et al.   JOURNAL OF ALZHEIMERS DISEASE

Charcot-Marie-Tooth 2b associated Rab7 mutations cause axon growth and guidance defects during vertebrate sensory neuron development

(2016) Olga Y. Ponomareva et al.   Neural Development

Multiple Roles of the Small GTPase Rab7

(2016) Flora Guerra et al.   Cells

Endocytic membrane trafficking and neurodegenerative disease

(2015) Andrea M. A. Schreij et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effects of endocytosis on receptor-mediated signaling

(2015) Roshanak Irannejad et al.   CURRENT OPINION IN CELL BIOLOGY

Rab, Arf, and Arl-Regulated Membrane Traffic in Cortical Neuron Migration

(2015) Bor Luen Tang   JOURNAL OF CELLULAR PHYSIOLOGY

Human Rab7 mutation mimics features of Charcot–Marie–Tooth neuropathy type 2B in Drosophila

(2014) Katrien Janssens et al.   NEUROBIOLOGY OF DISEASE

Vimentin phosphorylation and assembly are regulated by the small GTPase Rab7a

(2013) Laura Cogli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A novel RAB7 mutation in a Chinese family with Charcot–Marie–Tooth type 2B disease

(2013) Xing Wang et al.   GENE

Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway

(2013) G. Jacquemet et al.   JOURNAL OF CELL SCIENCE

Defective Axonal Transport of Rab7 GTPase Results in Dysregulated Trophic Signaling

(2013) K. Zhang et al.   JOURNAL OF NEUROSCIENCE

Rab7 Is Functionally Required for Selective Cargo Sorting at the Early Endosome

(2013) Emmanuelle Girard et al.   TRAFFIC

Charcot-Marie-Tooth 2B mutations in rab7 cause dosage-dependent neurodegeneration due to partial loss of function

(2013) Smita Cherry et al.   eLife

Charcot–Marie–Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin

(2012) Laura Cogli et al.   ACTA NEUROPATHOLOGICA

Molecular basis of Charcot–Marie–Tooth type 2B disease

(2012) Cecilia Bucci et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Rab7 Mutants Associated with Charcot-Marie-Tooth Disease Cause Delayed Growth Factor Receptor Transport and Altered Endosomal and Nuclear Signaling

(2012) Soumik BasuRay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autonomic nervous system involvement in a new CMT2B family

(2012) Fiore Manganelli et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

(2012) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Charcot–Marie–Tooth disease and intracellular traffic

(2012) Cecilia Bucci et al.   PROGRESS IN NEUROBIOLOGY

Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy

(2011) Ian G. Ganley et al.   Autophagy

Rac signaling in breast cancer: A tale of GEFs and GAPs

(2011) Eva Wertheimer et al.   CELLULAR SIGNALLING

Recent Advances in the Genetics of Hereditary Axonal Sensory-Motor Neuropathies Type 2

(2011) Senda Ajroud-Driss et al.   Current Neurology and Neuroscience Reports

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease

(2011) Stephen D. Ginsberg et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Charcot-Marie-Tooth disease

(2011) Mary M. Reilly et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

(2011) Ian G. Ganley et al.   MOLECULAR CELL

Cargo-Dependent Degradation of ESCRT-I as a Feedback Mechanism to Modulate Endosomal Sorting

(2011) Lene Malerød et al.   TRAFFIC

CMT2B-associated Rab7 mutants inhibit neurite outgrowth

(2010) Laura Cogli et al.   ACTA NEUROPATHOLOGICA

Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression

(2010) Stephen D. Ginsberg et al.   BIOLOGICAL PSYCHIATRY

The mood stabilizer valproic acid improves defective neurite formation caused by charcot-marie-tooth disease-associated mutant Rab7 through the JNK signaling pathway

(2010) Junji Yamauchi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Derivation of neural crest cells from human pluripotent stem cells

(2010) Gabsang Lee et al.   Nature Protocols

Rab GTPases-Dependent Endocytic Pathways Regulate Neuronal Migration and Maturation through N-Cadherin Trafficking

(2010) Takeshi Kawauchi et al.   NEURON

Rab7 Mutants Associated with Charcot-Marie-Tooth Disease Exhibit Enhanced NGF-Stimulated Signaling

(2010) Soumik BasuRay et al.   PLoS One

Peripherin and ATF3 genes are differentially regulated in regenerating and non-regenerating primary sensory neurons

(2009) Adam J. Reid et al.   BRAIN RESEARCH

Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation

(2009) Brett A. McCray et al.   HUMAN MOLECULAR GENETICS

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

(2009) M. N. J. Seaman et al.   JOURNAL OF CELL SCIENCE

Charcot-Marie-Tooth Disease: A Clinico-genetic Confrontation

(2008) N. Barisic et al.   ANNALS OF HUMAN GENETICS

Cathepsin D: A cellular roadmap

(2008) Nousheen Zaidi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of the Rab7K157N mutant protein associated with Charcot–Marie-Tooth type 2B

(2008) Azzurra De Luca et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cathepsin D—Many functions of one aspartic protease

(2008) Petr Benes et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

The regulation of cell motility and chemotaxis by phospholipid signaling

(2008) V. Kolsch et al.   JOURNAL OF CELL SCIENCE

Sorting of EGF and transferrin at the plasma membrane and by cargo-specific signaling to EEA1-enriched endosomes

(2008) D. Leonard et al.   JOURNAL OF CELL SCIENCE

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

(2008) M. R. Spinosa et al.   JOURNAL OF NEUROSCIENCE