Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose

Early detection of pre-malignant lesions in a KRASG12D-driven mouse lung cancer model by monitoring circulating free DNA

(2019) Callum P. Rakhit et al.   Disease Models & Mechanisms

The diverse origins of circulating cell-free DNA in the human body: a critical re-evaluation of the literature

(2018) Janine Aucamp et al.   BIOLOGICAL REVIEWS

Liver- and Colon-Specific DNA Methylation Markers in Plasma for Investigation of Colorectal Cancers With or Without Liver Metastases

(2018) Wanxia Gai et al.   CLINICAL CHEMISTRY

Non invasive prenatal diagnosis of fetal aneuploidy using cell free fetal DNA

(2018) Barbara Renga   European Journal of Obstetrics & Gynecology and Reproductive Biology

Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract

(2018) Philip Burnham et al.   Nature Communications

Non-invasive detection of human cardiomyocyte death using methylation patterns of circulating DNA

(2018) Hai Zemmour et al.   Nature Communications

New method to preserve the original proportion and integrity of urinary cell-free DNA

(2018) Pei Li et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Characteristics, properties, and potential applications of circulating cell-free dna in clinical diagnostics: a focus on transplantation

(2018) Karen Sherwood et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients

(2018) Bente Risberg et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Current and future perspectives of liquid biopsies in genomics-driven oncology

(2018) Ellen Heitzer et al.   NATURE REVIEWS GENETICS

Enhanced detection of circulating tumor DNA by fragment size analysis

(2018) Florent Mouliere et al.   Science Translational Medicine

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

(2018) Joshua Moss et al.   Nature Communications

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

(2017) Christopher Abbosh et al.   NATURE

Direct detection of early-stage cancers using circulating tumor DNA

(2017) Jillian Phallen et al.   Science Translational Medicine

Origins, structures, and functions of circulating DNA in oncology

(2016) A. R. Thierry et al.   CANCER AND METASTASIS REVIEWS

Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin

(2016) Matthew W. Snyder et al.   CELL

Identification of tissue-specific cell death using methylation patterns of circulating DNA

(2016) Roni Lehmann-Werman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Long and Short of Circulating Cell-Free DNA and the Ins and Outs of Molecular Diagnostics

(2016) Peiyong Jiang et al.   TRENDS IN GENETICS

Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues

(2015) Cleanthe Spanaki et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments

(2015) Kun Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noninvasive Prenatal Screening for Genetic Diseases Using Massively Parallel Sequencing of Maternal Plasma DNA

(2015) Lyn S. Chitty et al.   Cold Spring Harbor Perspectives in Medicine

Correlation between cell free DNA levels and medical evaluation of disease progression in systemic lupus erythematosus patients

(2014) Suzan Tug et al.   CELLULAR IMMUNOLOGY

Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital

(2013) Daniel J. Antoine et al.   HEPATOLOGY

Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial

(2013) D Nicholas Bateman et al.   LANCET

Acute Liver Failure

(2013) William Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Assessment of Emerging Biomarkers of Liver Injury in Human Subjects

(2013) Shelli Schomaker et al.   TOXICOLOGICAL SCIENCES

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

(2012) Mitchell R. McGill et al.   JOURNAL OF CLINICAL INVESTIGATION

Primer3—new capabilities and interfaces

(2012) Andreas Untergasser et al.   NUCLEIC ACIDS RESEARCH

Increased levels of circulating DNA in patients with systemic autoimmune diseases: A possible marker of disease activity in Sjögren’s syndrome

(2011) E Bartoloni et al.   LUPUS

Analysis of conditional gene deletion using probe based Real-Time PCR

(2010) Britta Weis et al.   BMC BIOTECHNOLOGY

Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts

(2010) Alain R. Thierry et al.   NUCLEIC ACIDS RESEARCH