Review
Nursing
Yinchu Hu, Hong Lu, Lihua Ren, Minghui Yang, Meidi Shen, Jing Huang, Qifang Huang, Li Fu
Summary: This study reviewed and evaluated existing prediction models for perineal lacerations. The current models lack validation and clinical applicability. Future research should focus on external validation and the development of new models for second-degree perineal laceration.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2023)
Article
Medicine, General & Internal
Amandine Puissegur, Marie Accoceberry, Marion Rouzaire, Bruno Pereira, Marie Herault, Clement Bruhat, Amelie Delabaere, Denis Gallot
Summary: We conducted a retrospective case-control study to identify risk factors for early perineal suture breakdown in patients with perineal tear or episiotomy complication. Instrumental delivery and a longer second phase of labor were confirmed as risk factors for early perineal suture breakdown.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Suna Yildirim Karaca, Mehmet Adiyeke, Alper Ileri, Tayfun Vural, Ayse Rabia Senkaya, Hande Ileri, Mehmet Ozeren
Summary: This study aimed to investigate the incidence and risk factors of obstetric perineal tears in adolescent pregnant patients during vaginal delivery. The results showed that nulliparity, high birth weight, and labor induction were significant risk factors for perineal tears in adolescents. However, spontaneous onset of labor and previous delivery appeared to reduce the risk of severe perineal tears.
JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY
(2022)
Article
Medicine, General & Internal
Yoav Baruch, Ronen Gold, Hagit Eisenberg, Hadar Amir, Lee Reicher, Yariv Yogev, Asnat Groutz
Summary: This study aimed to compare the incidence and clinical characteristics of obstetric anal sphincter injuries (OASI) between Asian and Caucasian women. The study found that Asian women had a higher rate of OASI, particularly fourth-degree injuries, and they gave birth to smaller newborns.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Lisa Kogner, Louise Lundborg, Xingrong Liu, Linnea V. Ladfors, Mia Ahlberg, Olof Stephansson, Anna Sandstrom
Summary: This study found that increasing duration of the active first stage of labor is associated with maternal complications in the early postpartum period. The risks of severe perineal lacerations, postpartum infection, and urinary retention increased with longer active first stage duration, while the risk of hematoma or ruptured sutures did not seem to be affected.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Obstetrics & Gynecology
Douglas Luchristt, Ana Rebecca Meekins, Congwen Zhao, Chad Grotegut, Nazema Y. Siddiqui, Brooke Alhanti, John Eric Jelovsek
Summary: Obstetric anal sphincter injuries (OASIS) can be accurately predicted based on information available at the time of admission for labour, and these predictions could be useful for selectively implementing prevention strategies.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Taylor S. Freret, Kaitlyn James, Anjali J. Kaimal
Summary: This study aimed to determine the rate of antibiotic administration for obstetric anal sphincter injuries, identify factors associated with antibiotic administration on the day of delivery, and assess the association between antibiotic use and wound complications. The study found that only about half of the women with obstetric anal sphincter injuries received antibiotics, and antibiotic administration was associated with a reduced rate of wound complications.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Obstetrics & Gynecology
Perrine Leborne, Renaud de Tayrac, Zakarya Zemmache, Chris Serrand, Pascale Fabbro-Peray, Lucie Allegre, Emmanuelle Vintejoux
Summary: This study aimed to evaluate the incidence of obstetric anal sphincter injuries (OASIs) following breech deliveries and compare it with cephalic presentation births. The results showed no significant difference in OASIs incidence between the breech and cephalic groups. Key message: Breech vaginal birth does not seem to be associated with a higher risk for obstetric anal sphincter injuries compared to a cephalic vaginal birth.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Obstetrics & Gynecology
Torbjorn M. Eggebo, Astrid Betten Rygh, Phillip von Brandis, Finn Egil Skjeldestad
Summary: This study investigates the effects of active perineal support and episiotomy on obstetric anal sphincter injury rates and the interaction between known risk factors. The results show a long-lasting reduction in OASIS rates after the implementation of preventive measures.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Public, Environmental & Occupational Health
Anna-Lena Stickelmann, Lieven Nils Kennes, Miriam Holscher, Charlotte Graef, Tomas Kupec, Julia Wittenborn, Elmar Stickeler, Laila Najjari
Summary: This study aimed to use transperineal ultrasound (TPUS) to detect and quantify obstetric anal sphincter injuries (OASIS) and monitor the healing process over a 6-month period. The results showed that a smaller tear size after 3 days of delivery indicates better healing after 6 months. Episiotomy appeared to prevent anal incontinence after 6 months.
Article
Obstetrics & Gynecology
Kristin Andre, Andrea Stuart, Karin Kallen
Summary: Primiparity, instrumental delivery, and high birthweight significantly increase the risk of OASIS, while obesity, low height, increasing age, and previous cesarean section also increase the risk. Smoking and low maternal educational level are associated with a lower OASIS rate.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2022)
Article
Obstetrics & Gynecology
V Ankarcrona, H. Zhao, B. Jacobsson, S. Brismar Wendel
Summary: A randomized controlled trial showed that lateral or mediolateral episiotomy can reduce the prevalence of OASIS in nulliparous women delivered with vacuum extraction, compared to women with no episiotomy. The study also found that third- and fourth-degree perineal injuries were reduced with episiotomy, with specific numbers needed to treat for each type of injury.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Obstetrics & Gynecology
Jiao Yi, Lei Chen, Xianglian Meng, Yi Chen
Summary: The study investigated the association between infection, cervical laceration, perineal laceration, and postpartum hemorrhage in women undergoing vaginal delivery induced by Cook balloon catheter. A retrospective study included 362 women diagnosed with postpartum hemorrhage after vaginal delivery at or beyond 37 weeks of gestation between February 2021 and May 2022. Risk factors were compared among different groups, and it was found that cervical laceration and perineal laceration increased the risk of postpartum hemorrhage in women with labor induction.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Albert Chao Chiet Tan, Faridah Binti Mohd Yusoff, Mohd Fairudzi Afzanizam Bin Salleh, Ai Chen Chua
Summary: This retrospective study analyzed 10 years of data and found that neonatal birthweight ≥3.5 kg was the most significant factor in predicting the severity of OASIS. Although the rates of reported complications were similar between the two groups after repair, significantly more expertise and resources were required for the repair of higher degree OASIS.
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2022)
Article
Obstetrics & Gynecology
Elliot M. Levine, Leah N. Delfinado, Madeleine Durand, David Rojas, Stephen Locher
Summary: The duration of the parturition process has an inverse association with the occurrence of obstetric anal sphincter injuries.
JOURNAL OF REPRODUCTIVE MEDICINE
(2021)
Article
Social Sciences, Interdisciplinary
Cathrine Axfors, Stavros I. Iliadis, Lovisa L. Rasmusson, Ulrika Beckman, Attila Fazekas, Louise Frisen, Lotta Sandstrom, Nils Thelin, Jeanette Wahlberg, Alkistis Skalkidou, Fotios C. Papadopoulos
Summary: This study aimed to describe the treatment preferences of individuals seeking health care for gender dysphoria in Sweden and found that preferences for gender affirming treatment varied according to perceived gender identity. The findings highlight the importance of individualized care and flexible treatment options for transgender individuals.
SEXUALITY RESEARCH AND SOCIAL POLICY
(2023)
Article
Cardiac & Cardiovascular Systems
Maria A. Karalexi, Thomas Frisell, Sven Cnattingius, Dag Holmberg, Mats Holmberg, Natasa Kollia, Alkistis Skalkidou, Fotios C. Papadopoulos
Summary: This study compared the incidence of cardiovascular disease (CVD) in transgender individuals with gender dysphoria (GD) who received gender-affirming hormone therapy (GAHT) with those without GAHT and the general population. The results showed that the incidence of CVD was low among transgender individuals with GD/GAHT, although it was higher compared to those without GD and similar to those with GD but no GAHT. This suggests that there may not be a causal relationship between GAHT treatment and CVD outcomes. Larger studies with longer follow-up are needed to confirm these findings.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Psychiatry
Susanne Lager, Karin Giden, Cathrine Axfors, Frida Sigvardsson, Natasa Kollia, Ingrid Nylander, Emma Fransson, Alkistis Skalkidou
Summary: This study aimed to investigate the association between alcohol consumption and symptoms of postpartum depression and anxiety. The results showed no significant association between postpartum alcohol consumption and mood symptoms. This lack of association may be attributed to long-term policy work and high participation in Swedish maternity care.
ARCHIVES OF WOMENS MENTAL HEALTH
(2022)
Article
Medicine, General & Internal
Emma Fransson, Unnur Gudnadottir, Luisa W. Hugerth, Eva Wiberg Itzel, Marica Hamsten, Fredrik Boulund, Alexandra Pennhag, Juan Du, Ina Schuppe-Koistinen, Nele Brusselaers, Lars Engstrand
Summary: The SweMaMi project aims to understand the dynamics of the microbiome during pregnancy through longitudinal sampling, metagenomics, questionnaires, and health registry linkage. With over 5000 pregnant participants, the project has collected a large number of microbiome samples and information. The next steps involve characterizing the microbial DNA and exploring the role of the microbiome in maternal and neonatal outcomes and early-childhood diseases.
Article
Psychiatry
Trine Munk-Olsen, Xiaoqin Liu, Kathrine Bang Madsen, Mette-Marie Zacher Kjeldsen, Liselotte Vogdrup Petersen, Veerle Bergink, Alkistis Skalkidou, Simone N. Vigod, Vibe G. Frokjaer, Carsten B. Pedersen, Merete L. Maegbaek
Summary: The study aimed to develop and validate an individualized prediction model for postpartum depression (PPD), using various predictors to identify the likelihood of an individual developing PPD. The recalibrated Extended model, with 14 variables, achieved the highest performance in terms of calibration and discrimination, with previous psychiatric history, maternal age, low education, and hyperemesis gravidarum being the most important predictors.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Public, Environmental & Occupational Health
Andrea Hess Engstrom, Nina Bohm-Starke, Merit Kullinger, Ulf Hogberg, Monica Buhrman, Alkistis Skalkidou, Margareta Widarsson
Summary: The study aimed to describe women's experiences before, under, and after a guided internet-based intervention for vulvodynia. The findings revealed that women often dealt with pain alone before the internet-based treatment, and had negative experiences with healthcare. However, during the treatment process, they found new ways to manage vulvodynia and felt empowered to take control. After the intervention, the women reported improvements in wellbeing and better strategies to manage pain, but felt that the treatment was insufficient to perceive changes in vulvar pain.
SEXUAL & REPRODUCTIVE HEALTHCARE
(2022)
Article
Public, Environmental & Occupational Health
Frida Viirman, Susanne Hesselman, Anna-Karin Wikstrom, Agneta Skoog Svanberg, Alkistis Skalkidou, Inger Sundstrom Poromaa, Anna Wikman
Summary: This study examined the impact of risk factors from three different time periods during pregnancy on negative childbirth experience, highlighting the significance of poor self-rated health, psychiatric care during pregnancy, and fear of childbirth in contributing to negative birth experiences.
SEXUAL & REPRODUCTIVE HEALTHCARE
(2022)
Article
Obstetrics & Gynecology
K. C. Ashish, Ankit Acharya, Pratiksha Bhattarai, Omkar Basnet, Anisha Shrestha, Garima Rijal, Alkistis Skalkidou
Summary: Disrespectful care after childbirth was strongly associated with postpartum depression symptoms irrespective of COVID-19 exposure during pregnancy. Caregivers, even during the global pandemic, should continue to focus their attention for immediate breast feeding and skin-to-skin contact, as this might reduce the risk for depressive symptoms postpartum.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Obstetrics & Gynecology
Unnur Gudnadottir, Juan Du, Luisa W. W. Hugerth, Lars Engstrand, Ina Schuppe-Koistinen, Eva Wiberg Itzel, Emma Fransson, Nele Brusselaers
Summary: This study aims to identify factors associated with pre-pregnancy complications and poor well-being in early pregnancy. Findings from an online questionnaire survey in Sweden showed a high incidence of pre-pregnancy complications, with risk factors including diagnosed endometriosis, thyroid medication, opioids and other strong pain medication, body mass index > 25 kg/m², and age over 35 years. Different subgroups of pre-pregnancy complications had unique risk factors, and women with recurrent pregnancy loss had a higher risk of depression in their current pregnancy.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Obstetrics & Gynecology
Lina Radmark, Walter Osika, Martin Benka Wallen, Eva Nissen, Gunilla Lonnberg, Richard Branstrom, Eva Henje, Renee Gardner, Emma Fransson, Hakan Karlsson, Maria Niemi
Summary: This study aimed to assess the effects of a Mindfulness Childbirth and Parenting (MBCP) intervention on heart rate variability (HRV), serum inflammatory markers, and self-assessed mental health. The results showed that participants who received MBCP reported a significant reduction in perceived stress and an increase in mindfulness compared to the control group. However, the intervention had no significant effect on postnatal depression, inflammatory serum markers, or HRV measures in this sub-study.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Health Care Sciences & Services
Janneke van t Hooft, Charlotte E. van Dijk, Cathrine Axfors, Zarko Alfirevic, Martijn A. Oudijk, Ben W. . J. Mol, Patrick M. Bossuyt, John P. A. Ioannidis
Summary: By evaluating randomized controlled trials on preterm birth prevention, it was found that only 10% of the trials met more than half of the usefulness criteria, but there was improvement over time. Future research planning should focus on using informative outcomes, patient-centeredness, pragmatism, and transparency.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Meeting Abstract
Oncology
Johanna Norenhag, Gabriella Edfeldt, Juan Du, Karin Stalberg, Fabricio Garcia, Luisa Warchavchik Hugerth, Lars Engstrand, Ina Schuppe Koistinen, Emma Fransson, Matts Olovsson
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2022)
Article
Immunology
Emma Brann, Alkistis Skalkidou, Jaclyn Schwarz, Fotios C. Papadopoulos, Emma Fransson, Inger Sundstrom Poromaa
Summary: This study aimed to investigate cytokine levels during pregnancy in women with different trajectories of depressive symptoms peripartum, and compare them to levels of non-pregnant controls. The results showed that cytokine levels were higher during pregnancy and delivery compared to non-pregnant controls, but returned to non-pregnant levels by postpartum week 8 for some cytokines. Women with peripartum depressive symptoms had lower levels of VEGF-A compared to non-depressed women, and the severity and trajectory of depressive symptoms influenced VEGF-A levels.
BRAIN, BEHAVIOR, & IMMUNITY - HEALTH
(2022)