期刊
ARCHIVES OF MICROBIOLOGY
卷 202, 期 6, 页码 1349-1357出版社
SPRINGER
DOI: 10.1007/s00203-020-01846-7
关键词
Lactobacillus; Adhesion; Aggregation; Physicochemical properties; Caco-2 cell; Oral keratinocyte H357 cell
类别
资金
- National Research Council of Thailand [(DEN600045b)] Funding Source: Medline
- Thailand Research Fund (TRF) through the Royal Golden Jubilee PhD program [(PhD/0217/2553/AN.2)] Funding Source: Medline
- National Science and Technology Development Agency [(Co-project, 2017)] Funding Source: Medline
This study aimed to assess adhesion and anti-adhesion, aggregation, and surface properties of four selected oralLactobacillusstrains,L. fermentumSD7,L. paracaseiSD1,L. rhamnosusSD4, andL. rhamnosusSD11, together withLactobacillus rhamnosusGG. Human cells, enterocytes Caco-2 and oral keratinocyte H357 were used, and various enteric and oral pathogens were included. Results showed that allLactobacillustested gave high adhesion and internalization in both Caco-2 and H357 cells similar toL. rhamnosusGG, and it suggests that such properties are strain dependent and specific to host cells. Anti-adhesion was different; it depended on the internalization ability of individualLactobacillusand pathogenic strains to Caco-2 and H357. Coaggregation ability depended on autoaggregation of both theLactobacillusand pathogenic strains. A positive correlation between surface charges and aggregation, and internalization and anti-adhesion of allLactobacilluswas found. In conclusion, results suggests that the selectedLactobacillusmight be potential probiotics for usage in both the oral cavity and intestinal tract due to their abilities of aggregation, adherence and anti-internalization to both Caco-2 and H357 cells.
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