Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease

Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve

(2016) Russell A. Gould et al.   CURRENT BIOLOGY

Wnt/β-catenin signaling enables developmental transitions during valvulogenesis

(2016) Fernanda M. Bosada et al.   DEVELOPMENT

Deletion of Periostin Protects Against Atherosclerosis in Mice by Altering Inflammation and Extracellular Matrix Remodeling

(2015) Jennifer A. Schwanekamp et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Nonbiased Molecular Screening Identifies Novel Molecular Regulators of Fibrogenic and Proliferative Signaling in Myxomatous Mitral Valve DiseaseCLINICAL PERSPECTIVE

(2015) Nassir M. Thalji et al.   Circulation-Cardiovascular Genetics

Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation

(2015) Caitlin J. Bowen et al.   DEVELOPMENTAL BIOLOGY

The β-catenin signaling pathway induces aggressive potential in breast cancer by up-regulating the chemokine CCL5

(2015) Rika Yasuhara et al.   EXPERIMENTAL CELL RESEARCH

Nonbiased Molecular Screening Identifies Novel Molecular Regulators of Fibrogenic and Proliferative Signaling in Myxomatous Mitral Valve DiseaseCLINICAL PERSPECTIVE

(2015) Nassir M. Thalji et al.   Circulation-Cardiovascular Genetics

Loss of β-Catenin Promotes Chondrogenic Differentiation of Aortic Valve Interstitial Cells

(2014) Ming Fang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Crosstalk between fibroblasts and inflammatory cells

(2014) S. Van Linthout et al.   CARDIOVASCULAR RESEARCH

Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes

(2014) Gaëlle Odelin et al.   CARDIOVASCULAR RESEARCH

Wnt-3a-activated human fibroblasts promote human keratinocyte proliferation and matrix destruction

(2014) Katrin Sobel et al.   INTERNATIONAL JOURNAL OF CANCER

Developmental basis for filamin-A-associated myxomatous mitral valve disease

(2012) Kimberly Sauls et al.   CARDIOVASCULAR RESEARCH

Modulation of Transforming Growth Factor-  Signaling and Extracellular Matrix Production in Myxomatous Mitral Valves by Angiotensin II Receptor Blockers

(2012) A. Geirsson et al.   CIRCULATION

A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse

(2011) Anna Ferrer-Vaquer et al.   BMC DEVELOPMENTAL BIOLOGY

Human myxomatous mitral valve prolapse: Role of bone morphogenetic protein 4 in valvular interstitial cell activation

(2011) Rachana Sainger et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Wnt signaling in heart valve development and osteogenic gene induction

(2009) Christina M. Alfieri et al.   DEVELOPMENTAL BIOLOGY