Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers

Inherited genetic variation in childhood acute lymphoblastic leukemia

(2015) T. Moriyama et al.   BLOOD

A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cells

(2015) Jean-François Spinella et al.   BMC CANCER

Advances in the translational genomics of neuroblastoma: From improving risk stratification and revealing novel biology to identifying actionable genomic alterations

(2015) Kristopher R. Bosse et al.   CANCER

A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution

(2015) K. M. Walsh et al.   CANCER RESEARCH

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

(2015) Chenan Zhang et al.   HUMAN MOLECULAR GENETICS

Telomerase activation by genomic rearrangements in high-risk neuroblastoma

(2015) Martin Peifer et al.   NATURE

Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism

(2015) Derek A. Oldridge et al.   NATURE

TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors

(2015) Linda J Valentijn et al.   NATURE GENETICS

Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

(2015) Matthew H Law et al.   NATURE GENETICS

Telomere maintenance and the etiology of adult glioma

(2015) Kyle M. Walsh et al.   NEURO-ONCOLOGY

Germline Mutations in Predisposition Genes in Pediatric Cancer

(2015) Jinghui Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

(2015) Jeanette E. Eckel-Passow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

(2015) C. Tomasetti et al.   SCIENCE

Mendelian randomization studies in coronary artery disease

(2014) H. Jansen et al.   EUROPEAN HEART JOURNAL

The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length

(2014) Mark M. Iles et al.   JNCI-Journal of the National Cancer Institute

Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk

(2014) Kyle M Walsh et al.   NATURE GENETICS

Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma

(2014) Xiang Chen et al.   Cell Reports

Novel childhood ALL susceptibility locus BMI1-PIP4K2A is specifically associated with the hyperdiploid subtype

(2013) K. M. Walsh et al.   BLOOD

Genome-wide association study identifies two susceptibility loci for osteosarcoma

(2013) Sharon A Savage et al.   NATURE GENETICS

A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia

(2013) Helen E Speedy et al.   NATURE GENETICS

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

(2013) Virginia Perez-Andreu et al.   NATURE GENETICS

Identification of seven loci affecting mean telomere length and their association with disease

(2013) Veryan Codd et al.   NATURE GENETICS

Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis

(2013) K. M. Walsh et al.   NEURO-ONCOLOGY

Telomeres shorten at equivalent rates in somatic tissues of adults

(2013) Lily Daniali et al.   Nature Communications

Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia

(2012) J. J. Yang et al.   BLOOD

Heritability in the genome-wide association era

(2012) Noah Zaitlen et al.   HUMAN GENETICS

Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

(2012) Massimo Mangino et al.   HUMAN MOLECULAR GENETICS

Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma

(2012) Nai-Kong V. Cheung   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Telomerase Reverse Transcriptase Locus Polymorphisms and Cancer Risk: A Field Synopsis and Meta-Analysis

(2012) Simone Mocellin et al.   JNCI-Journal of the National Cancer Institute

A genome-wide association study identifies susceptibility loci for Wilms tumor

(2012) Clare Turnbull et al.   NATURE GENETICS

Walking the Walk from Genes through Telomere Maintenance to Cancer Risk

(2011) E. H. Blackburn   Cancer Prevention Research

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia

(2011) Jun J Yang et al.   NATURE GENETICS

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Common variants near TERC are associated with mean telomere length

(2010) Veryan Codd et al.   NATURE GENETICS

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology

(2010) D. Levy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics