期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 362, 期 18, 页码 3795-3823出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.202000285
关键词
Aerobic oxidation; Indole derivatives; C-H activation; Nucleophilic addition; Radical coupling
资金
- National Natural Science Foundation of China [21801076, 21602187]
- Normal Project Foundation of Hunan Provincial Education Department [18C0845]
- Hunan Provincial Natural Science Foundation of China [2019JJ50415]
- Science and Technology Planning Project of Hunan Province [2019RS2039]
The synthetic methodology for direct indole functionalizations is of great significance in indole chemistry and has been intensively investigated in the last few decades. From the perspective of green chemistry, oxygen is the best choice as the terminal oxidant in molecular synthesis. Hence, aerobic oxidative functionalization of indoles became a hot research topic in the last decade. Numerous efficient protocols in this field have been discovered that enable facile and efficient transformations of indoles to related valuable compounds, which are summarized and discussed in detail in this review.
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